GB1493459A - Non-antigenic non-thrombogenic infection resistant grafts from umbilical cord vessels and process for preparing sam - Google Patents

Non-antigenic non-thrombogenic infection resistant grafts from umbilical cord vessels and process for preparing sam

Info

Publication number
GB1493459A
GB1493459A GB28540/75A GB2854075A GB1493459A GB 1493459 A GB1493459 A GB 1493459A GB 28540/75 A GB28540/75 A GB 28540/75A GB 2854075 A GB2854075 A GB 2854075A GB 1493459 A GB1493459 A GB 1493459A
Authority
GB
United Kingdom
Prior art keywords
prosthesis
segment
umbilical cord
patch
dardik
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28540/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/543,462 external-priority patent/US3974526A/en
Priority claimed from US05/563,998 external-priority patent/US3988782A/en
Application filed by Individual filed Critical Individual
Publication of GB1493459A publication Critical patent/GB1493459A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1493459 Prosthesis derived from umbilical cord I I DARDIK and H DARDIK 7 July 1975 [23 Jan 1975 1 April 1975] 28540/75 Heading A5R A prosthesis, e.g. a vein, artery or patch, is formed by removing one of the principal blood vessels from an umbilical cord, subjecting a segment of said blood vessels to a tanning treatment, for example by contacting it with an aldehyde selected from glutaraldehyde, formaldehyde, dialdehyde starch and glyoxal, treating the hardened segment to remove residual aldehyde and shaping the segment to the required prosthetic form. The segment may be shaped on a cylindrical or tapered mandrel to provide tubular prostheses for use as veins, arteries, or urethia and may be reinforced by an exterior mesh coating of a polyester or flurocarbon plastics. Alternatively the prosthesis may be in the form of a strip which is used to reinforce the join of an anastomosis, for lining the pericardium of the heart, as a heart valve or for covering an implant e.g. a pacemaker. The prosthesis may also be in the form of a patch which is sewn to the skin over a wound, e.g. a burn, healing taking place beneath the patch which is sloughed off on completion of healing. The agent to remove residual aldehyde may be an amino acid, or an alkali salt thereof, an amine, a hydroxylamine, a peracid, a peroxide or a hypochlorite.
GB28540/75A 1975-01-23 1975-07-07 Non-antigenic non-thrombogenic infection resistant grafts from umbilical cord vessels and process for preparing sam Expired GB1493459A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/543,462 US3974526A (en) 1973-07-06 1975-01-23 Vascular prostheses and process for producing the same
US05/563,998 US3988782A (en) 1973-07-06 1975-04-01 Non-antigenic, non-thrombogenic infection-resistant grafts from umbilical cord vessels and process for preparing and using same

Publications (1)

Publication Number Publication Date
GB1493459A true GB1493459A (en) 1977-11-30

Family

ID=27067341

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28540/75A Expired GB1493459A (en) 1975-01-23 1975-07-07 Non-antigenic non-thrombogenic infection resistant grafts from umbilical cord vessels and process for preparing sam

Country Status (14)

Country Link
JP (1) JPS521011A (en)
AT (1) ATA541675A (en)
AU (1) AU497462B2 (en)
BR (1) BR7504424A (en)
CA (1) CA1055843A (en)
DE (1) DE2531588C2 (en)
DK (1) DK140086B (en)
ES (1) ES441295A1 (en)
FR (1) FR2298312A1 (en)
GB (1) GB1493459A (en)
IL (1) IL47667A (en)
NL (1) NL7508306A (en)
NO (1) NO752465L (en)
SE (1) SE7508047L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174909A (en) * 1985-03-04 1986-11-19 American Hospital Supply Corp A method of treating bone fractures to reduce formation of fibrous adhesions

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2902434C2 (en) * 1978-01-26 1986-10-16 Arthur August Roseville Minn. Beisang Method of manufacturing a blood vessel implant
FR2502489A1 (en) * 1981-03-30 1982-10-01 Ufim I Glaznykh Bolezn Homo:transplant material, esp. for conjunctiva - comprising retro:peritoneal fascia tissue
FR2523810B1 (en) * 1982-03-23 1988-11-25 Carpentier Alain ORGANIC GRAFT FABRIC AND PROCESS FOR ITS PREPARATION
ZA843751B (en) * 1983-06-10 1984-12-24 University Patents Inc Body implants of extracellular matrix and means and methods of making and using such implants
DE3480693D1 (en) * 1983-10-20 1990-01-18 Vettivetpillai Ketharanathan Biomaterial.
US4786287A (en) * 1986-10-10 1988-11-22 Baxter Travenol Laboratories Process for decreasing residual aldehyde levels in implantable bioprosthetic tissue
CN113733532B (en) * 2021-08-25 2022-10-11 中山大学 Flexible polyester patch and preparation method and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2174909A (en) * 1985-03-04 1986-11-19 American Hospital Supply Corp A method of treating bone fractures to reduce formation of fibrous adhesions

Also Published As

Publication number Publication date
DE2531588C2 (en) 1983-11-03
ES441295A1 (en) 1977-03-16
IL47667A0 (en) 1975-10-15
NL7508306A (en) 1976-07-27
FR2298312A1 (en) 1976-08-20
DK140086B (en) 1979-06-18
AU8296975A (en) 1977-01-13
SE7508047L (en) 1976-07-26
AU497462B2 (en) 1978-12-14
ATA541675A (en) 1979-02-15
DK318975A (en) 1976-07-24
JPS6122981B2 (en) 1986-06-03
IL47667A (en) 1978-04-30
NO752465L (en) 1976-07-26
DK140086C (en) 1979-11-12
DE2531588A1 (en) 1976-08-05
JPS521011A (en) 1977-01-06
CA1055843A (en) 1979-06-05
FR2298312B1 (en) 1978-07-28
BR7504424A (en) 1976-08-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee