GB1492073A - Pyrido(3,2-e)-as-triazine derivatives - Google Patents
Pyrido(3,2-e)-as-triazine derivativesInfo
- Publication number
- GB1492073A GB1492073A GB32908/75A GB3290875A GB1492073A GB 1492073 A GB1492073 A GB 1492073A GB 32908/75 A GB32908/75 A GB 32908/75A GB 3290875 A GB3290875 A GB 3290875A GB 1492073 A GB1492073 A GB 1492073A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrido
- hydrazides
- acyl
- alkyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1492073 Pyrido-[3,2-e]-as-triazines EGYT GYOGYSZERVEGYESZETI GYAR 6 Aug 1975 32908/75 Heading C2C The invention comprises compounds of Formula (I) and their pharmaceutically acceptable salts, wherein R is C 5-20 alkyl, Ph (optionally substituted by halogen, OH, NH 2 or by # 1 alkoxy) or Ph-C 1-4 -alkyl and either R 1 = R 2 = H (Ia) or R 1 -R 2 constitutes a further N-N bond (Ib). In examples, (Ia) are prepared by cyclizing the corresponding N<SP>1</SP>-acyl-N<SP>2</SP>-(3-aminopyrid-2-yl) hydrazides, and may be oxidized to (Ib). Also prepared are N<SP>1</SP>-acyl-N<SP>2</SP>-(3-nitropyrid-2-yl) hydrazides. Therapeutic compositions having antibacterial, antifungal, antiinflammatory and/or antimicrobial activity comprise compounds of the above formula.
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7508834A SE409456B (en) | 1975-08-05 | 1975-08-05 | ANALOGICAL PROCEDURE FOR THE PREPARATION OF PYRIDO (3,2-E) -AS-TRIAZINE DERIVATIVES |
DK356275AA DK138426B (en) | 1975-08-05 | 1975-08-05 | Analogous process for the preparation of pyrido (3,2-e) -as-triazine derivatives. |
GB32908/75A GB1492073A (en) | 1975-08-05 | 1975-08-06 | Pyrido(3,2-e)-as-triazine derivatives |
FI752294A FI59098C (en) | 1975-08-05 | 1975-08-13 | FRAME FOR THE PREPARATION OF THERAPEUTIC ANIMAL THERMAL PYRIDO (3,2-E) -ASTRIAZINDERIVAT |
AT636675A AT347958B (en) | 1975-08-05 | 1975-08-14 | PROCESS FOR THE PREPARATION OF NEW PYRIDO (3.2-E) -AS-TRIAZINE DERIVATIVES AND OF SALT OF THESE COMPOUNDS, FORMED WITH PHARMACEUTICAL ACIDS |
DE19752536387 DE2536387A1 (en) | 1975-08-05 | 1975-08-14 | PYRIDO (3,2-E) -AS-TRIAZINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING SUCH, AND METHOD FOR MANUFACTURING THE SAME |
CH1064575A CH617199A5 (en) | 1975-08-05 | 1975-08-15 | Process for the preparation of pyrido[3,2-e]-as-triazine derivatives |
DD187881A DD121323A5 (en) | 1975-08-05 | 1975-08-15 | |
JP50099878A JPS5225796A (en) | 1975-08-05 | 1975-08-19 | Production of pyrid *3*22e* asstriazine derivative |
BE159502A BE832791A (en) | 1975-08-05 | 1975-08-27 | DERIVATIVES OF PYRIDO (3,2-E) -AS-TRIAZINE AND PROCESS FOR THEIR PREPARATION. |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7508834A SE409456B (en) | 1975-08-05 | 1975-08-05 | ANALOGICAL PROCEDURE FOR THE PREPARATION OF PYRIDO (3,2-E) -AS-TRIAZINE DERIVATIVES |
DK356275AA DK138426B (en) | 1975-08-05 | 1975-08-05 | Analogous process for the preparation of pyrido (3,2-e) -as-triazine derivatives. |
GB32908/75A GB1492073A (en) | 1975-08-05 | 1975-08-06 | Pyrido(3,2-e)-as-triazine derivatives |
FI752294A FI59098C (en) | 1975-08-05 | 1975-08-13 | FRAME FOR THE PREPARATION OF THERAPEUTIC ANIMAL THERMAL PYRIDO (3,2-E) -ASTRIAZINDERIVAT |
AT636675A AT347958B (en) | 1975-08-05 | 1975-08-14 | PROCESS FOR THE PREPARATION OF NEW PYRIDO (3.2-E) -AS-TRIAZINE DERIVATIVES AND OF SALT OF THESE COMPOUNDS, FORMED WITH PHARMACEUTICAL ACIDS |
DE19752536387 DE2536387A1 (en) | 1975-08-05 | 1975-08-14 | PYRIDO (3,2-E) -AS-TRIAZINE DERIVATIVES, MEDICINAL PRODUCTS CONTAINING SUCH, AND METHOD FOR MANUFACTURING THE SAME |
CH1064575A CH617199A5 (en) | 1975-08-05 | 1975-08-15 | Process for the preparation of pyrido[3,2-e]-as-triazine derivatives |
DD187881A DD121323A5 (en) | 1975-08-05 | 1975-08-15 | |
JP50099878A JPS5225796A (en) | 1975-08-05 | 1975-08-19 | Production of pyrid *3*22e* asstriazine derivative |
BE159502A BE832791A (en) | 1975-08-05 | 1975-08-27 | DERIVATIVES OF PYRIDO (3,2-E) -AS-TRIAZINE AND PROCESS FOR THEIR PREPARATION. |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1492073A true GB1492073A (en) | 1977-11-16 |
Family
ID=27578944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB32908/75A Expired GB1492073A (en) | 1975-08-05 | 1975-08-06 | Pyrido(3,2-e)-as-triazine derivatives |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS5225796A (en) |
AT (1) | AT347958B (en) |
BE (1) | BE832791A (en) |
CH (1) | CH617199A5 (en) |
DD (1) | DD121323A5 (en) |
DE (1) | DE2536387A1 (en) |
DK (1) | DK138426B (en) |
FI (1) | FI59098C (en) |
GB (1) | GB1492073A (en) |
SE (1) | SE409456B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0159112A1 (en) * | 1984-02-21 | 1985-10-23 | Eli Lilly And Company | Process for the preparation of diaminopyridines |
WO2024094150A1 (en) * | 2022-11-04 | 2024-05-10 | Insilico Medicine Ip Limited | Nlrp3 inflammasome inhibitors and uses thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9916154B1 (en) * | 1998-12-01 | 2010-09-21 | 1,3,5 substituted triazines as well as method for controlling undesirable vegetation, use and herbicidal composition comprising them. |
-
1975
- 1975-08-05 DK DK356275AA patent/DK138426B/en not_active IP Right Cessation
- 1975-08-05 SE SE7508834A patent/SE409456B/en unknown
- 1975-08-06 GB GB32908/75A patent/GB1492073A/en not_active Expired
- 1975-08-13 FI FI752294A patent/FI59098C/en not_active IP Right Cessation
- 1975-08-14 DE DE19752536387 patent/DE2536387A1/en not_active Withdrawn
- 1975-08-14 AT AT636675A patent/AT347958B/en not_active IP Right Cessation
- 1975-08-15 CH CH1064575A patent/CH617199A5/en not_active IP Right Cessation
- 1975-08-15 DD DD187881A patent/DD121323A5/xx unknown
- 1975-08-19 JP JP50099878A patent/JPS5225796A/en active Pending
- 1975-08-27 BE BE159502A patent/BE832791A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0159112A1 (en) * | 1984-02-21 | 1985-10-23 | Eli Lilly And Company | Process for the preparation of diaminopyridines |
WO2024094150A1 (en) * | 2022-11-04 | 2024-05-10 | Insilico Medicine Ip Limited | Nlrp3 inflammasome inhibitors and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
SE409456B (en) | 1979-08-20 |
DK356275A (en) | 1977-02-06 |
BE832791A (en) | 1975-12-16 |
AT347958B (en) | 1979-01-25 |
DE2536387A1 (en) | 1977-02-24 |
ATA636675A (en) | 1978-06-15 |
SE7508834L (en) | 1977-02-06 |
JPS5225796A (en) | 1977-02-25 |
DK138426C (en) | 1979-02-12 |
DK138426B (en) | 1978-09-04 |
CH617199A5 (en) | 1980-05-14 |
FI59098C (en) | 1981-06-10 |
DD121323A5 (en) | 1976-07-20 |
FI59098B (en) | 1981-02-27 |
FI752294A (en) | 1977-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |