GB1488617A - Pharmaceutical composition - Google Patents
Pharmaceutical compositionInfo
- Publication number
- GB1488617A GB1488617A GB11989/75A GB1198975A GB1488617A GB 1488617 A GB1488617 A GB 1488617A GB 11989/75 A GB11989/75 A GB 11989/75A GB 1198975 A GB1198975 A GB 1198975A GB 1488617 A GB1488617 A GB 1488617A
- Authority
- GB
- United Kingdom
- Prior art keywords
- creatinine
- degrading
- urea
- uric acid
- species
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 6
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 abstract 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 3
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 3
- 229940109239 creatinine Drugs 0.000 abstract 3
- 244000000000 soil microbiome Species 0.000 abstract 3
- 229940116269 uric acid Drugs 0.000 abstract 3
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 abstract 2
- 239000004202 carbamide Substances 0.000 abstract 2
- 229960003624 creatine Drugs 0.000 abstract 2
- 239000006046 creatine Substances 0.000 abstract 2
- 230000000593 degrading effect Effects 0.000 abstract 2
- 241000894007 species Species 0.000 abstract 2
- QYPPJABKJHAVHS-UHFFFAOYSA-N Agmatine Natural products NCCCCNC(N)=N QYPPJABKJHAVHS-UHFFFAOYSA-N 0.000 abstract 1
- 241000589158 Agrobacterium Species 0.000 abstract 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- 239000002028 Biomass Substances 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 abstract 1
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000589516 Pseudomonas Species 0.000 abstract 1
- 241000589180 Rhizobium Species 0.000 abstract 1
- 241000607720 Serratia Species 0.000 abstract 1
- QYPPJABKJHAVHS-UHFFFAOYSA-P agmatinium(2+) Chemical compound NC(=[NH2+])NCCCC[NH3+] QYPPJABKJHAVHS-UHFFFAOYSA-P 0.000 abstract 1
- 229960000458 allantoin Drugs 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- 229960003121 arginine Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- 229960002989 glutamic acid Drugs 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 229960004198 guanidine Drugs 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229960003104 ornithine Drugs 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 229940045136 urea Drugs 0.000 abstract 1
- 229940075420 xanthine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2414156A DE2414156A1 (de) | 1974-03-23 | 1974-03-23 | Arzneimittel zur beseitigung uraemischer symptome und verfahren zu seiner herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1488617A true GB1488617A (en) | 1977-10-12 |
Family
ID=5911004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11989/75A Expired GB1488617A (en) | 1974-03-23 | 1975-03-21 | Pharmaceutical composition |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4022883A (cg-RX-API-DMAC7.html) |
| BE (1) | BE826982A (cg-RX-API-DMAC7.html) |
| CA (1) | CA1062611A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2414156A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2264557B1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1488617A (cg-RX-API-DMAC7.html) |
| LU (1) | LU72106A1 (cg-RX-API-DMAC7.html) |
| NL (1) | NL7503426A (cg-RX-API-DMAC7.html) |
| SE (1) | SE7503260L (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6706287B2 (en) | 2001-05-15 | 2004-03-16 | Kibow Biotech Inc. | Prebiotic and probiotic compositions and methods for their use in gut-based therapies |
| US7998470B2 (en) | 1999-04-30 | 2011-08-16 | Kibow Biotech, Inc. | Compositions and methods improving renal function |
| US9655932B2 (en) | 2002-03-13 | 2017-05-23 | Kibow Biotech, Inc. | Composition and method for preventing or treating gout or hyperuricemia |
| US11103542B2 (en) | 2002-03-13 | 2021-08-31 | Kibow Biotech, Inc. | Composition and method for maintaining healthy kidney function |
| US20050074442A1 (en) * | 2002-03-13 | 2005-04-07 | Natarajan Ranganathan | Compositions and methods for augmenting kidney function |
| US9980988B2 (en) * | 2002-03-13 | 2018-05-29 | Kibow Biotech, Inc. | Compositions and methods for augmenting kidney function |
| CN100402042C (zh) * | 2002-03-13 | 2008-07-16 | 基博生物技术公司 | 增强肾功能的组合物及方法 |
| CA2540467C (en) * | 2003-09-30 | 2013-11-12 | Kibow Biotech, Inc. | Compositions and methods for augmenting kidney function |
| US7198785B2 (en) * | 2003-12-09 | 2007-04-03 | Brown University | Systems and methods related to degradation of uremic toxins |
| EP1913946B1 (en) | 2005-07-08 | 2014-03-05 | Toray Industries, Inc. | Therapeutic agent and treatment method for ameliorating uremia |
| JP5017271B2 (ja) * | 2006-08-21 | 2012-09-05 | カルピス株式会社 | 腎機能改善剤 |
| MX369877B (es) * | 2013-02-04 | 2019-11-25 | Seres Therapeutics Inc | Composiciones y metodos. |
| WO2018125735A1 (en) | 2016-12-29 | 2018-07-05 | Kibow Biotech, Inc. | Composition and method for maintaining healthy kidney function |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3701830A (en) * | 1971-02-26 | 1972-10-31 | Monsanto Co | Method for improving oral health and hygiene in dogs and cats |
| JPS5226076B2 (cg-RX-API-DMAC7.html) * | 1972-10-06 | 1977-07-12 |
-
1974
- 1974-03-23 DE DE2414156A patent/DE2414156A1/de not_active Withdrawn
-
1975
- 1975-03-18 US US05/559,525 patent/US4022883A/en not_active Expired - Lifetime
- 1975-03-21 NL NL7503426A patent/NL7503426A/xx not_active Application Discontinuation
- 1975-03-21 LU LU72106A patent/LU72106A1/xx unknown
- 1975-03-21 BE BE154585A patent/BE826982A/xx unknown
- 1975-03-21 GB GB11989/75A patent/GB1488617A/en not_active Expired
- 1975-03-21 FR FR7508848A patent/FR2264557B1/fr not_active Expired
- 1975-03-21 SE SE7503260A patent/SE7503260L/xx unknown
- 1975-03-24 CA CA222,929A patent/CA1062611A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2264557A1 (cg-RX-API-DMAC7.html) | 1975-10-17 |
| LU72106A1 (cg-RX-API-DMAC7.html) | 1975-08-20 |
| DE2414156A1 (de) | 1975-09-25 |
| FR2264557B1 (cg-RX-API-DMAC7.html) | 1978-08-04 |
| CA1062611A (en) | 1979-09-18 |
| SE7503260L (cg-RX-API-DMAC7.html) | 1975-09-24 |
| US4022883A (en) | 1977-05-10 |
| NL7503426A (nl) | 1975-09-25 |
| BE826982A (fr) | 1975-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |