GB1482049A - Bicyclohexane derivatives for use in the synthesis of prostaglandins - Google Patents

Bicyclohexane derivatives for use in the synthesis of prostaglandins

Info

Publication number
GB1482049A
GB1482049A GB4889576A GB4889576A GB1482049A GB 1482049 A GB1482049 A GB 1482049A GB 4889576 A GB4889576 A GB 4889576A GB 4889576 A GB4889576 A GB 4889576A GB 1482049 A GB1482049 A GB 1482049A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compounds
formula
rco
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4889576A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1482049A publication Critical patent/GB1482049A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
GB4889576A 1974-07-12 1975-06-11 Bicyclohexane derivatives for use in the synthesis of prostaglandins Expired GB1482049A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48829574A 1974-07-12 1974-07-12
US55270775A 1975-02-24 1975-02-24

Publications (1)

Publication Number Publication Date
GB1482049A true GB1482049A (en) 1977-08-03

Family

ID=27049301

Family Applications (3)

Application Number Title Priority Date Filing Date
GB4889576A Expired GB1482049A (en) 1974-07-12 1975-06-11 Bicyclohexane derivatives for use in the synthesis of prostaglandins
GB2494075A Expired GB1482047A (en) 1974-07-12 1975-06-11 Bicyclohexane derivatives for use in the synthesis of prostaglandins
GB4889476A Expired GB1482048A (en) 1974-07-12 1975-06-11 Oxatricyclooctane derivatives for use in the synthesis of prostaglandins

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB2494075A Expired GB1482047A (en) 1974-07-12 1975-06-11 Bicyclohexane derivatives for use in the synthesis of prostaglandins
GB4889476A Expired GB1482048A (en) 1974-07-12 1975-06-11 Oxatricyclooctane derivatives for use in the synthesis of prostaglandins

Country Status (6)

Country Link
JP (1) JPS5134146A (enExample)
CH (2) CH619922A5 (enExample)
DE (1) DE2530221A1 (enExample)
FR (3) FR2285385A1 (enExample)
GB (3) GB1482049A (enExample)
NL (1) NL7508301A (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029681A (en) * 1976-02-13 1977-06-14 The Upjohn Company 13,14-Didehydro-PG analogs

Also Published As

Publication number Publication date
DE2530221A1 (de) 1976-01-29
FR2285364B1 (enExample) 1980-07-18
FR2285385A1 (fr) 1976-04-16
JPS5134146A (ja) 1976-03-23
NL7508301A (nl) 1976-01-14
FR2285385B1 (enExample) 1979-03-09
GB1482048A (en) 1977-08-03
CH619922A5 (en) 1980-10-31
FR2285373B1 (enExample) 1980-07-18
GB1482047A (en) 1977-08-03
FR2285364A1 (fr) 1976-04-16
FR2285373A1 (fr) 1976-04-16
AU8243775A (en) 1977-01-06
CH615923A5 (en) 1980-02-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee