GB1481595A - Substituted benzopyranopyridines - Google Patents

Substituted benzopyranopyridines

Info

Publication number
GB1481595A
GB1481595A GB22953/76A GB2295376A GB1481595A GB 1481595 A GB1481595 A GB 1481595A GB 22953/76 A GB22953/76 A GB 22953/76A GB 2295376 A GB2295376 A GB 2295376A GB 1481595 A GB1481595 A GB 1481595A
Authority
GB
United Kingdom
Prior art keywords
alkyl
benzopyranopyridines
compounds
substituted
june
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB22953/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of GB1481595A publication Critical patent/GB1481595A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

1481595 Benzopyranopyridines WARNERLAMBERT CO 3 June 1976 [13 June 1975] 22953/76 Heading C2C The invention comprises compounds of formula and their pharmacologically compatible acid addition salts, wherein R 1 and R 2 are each H, OH or C 1-6 alkyl or alkoxy, or R 1 -R 2 forms - OCH 2 O-; and R 3 is piperidino which is either (a) monosubstituted by C 1-6 alkyl, aryl-C 1-6 - alkyl or COX, X being OH, C 1-6 alkoxy, NH 2 , NH(C 1-6 alkyl) or N(C 1-6 alkyl)2, or (b) 2,2-di- or 2,2,6,6 - tetra - substituted by C 1-6 alkyl. These compounds are prepared by reacting N- unsubstituted benzopyranopyridines with the intermediates ClCH 2 CH 2 R 3 . The preparation of starting materials HOCH 2 CH 2 R 3 . is also described. Therapeutic compositions having brochodilator activity comprise compounds of the above formula and may be administered orally or parenterally.
GB22953/76A 1975-06-13 1976-06-03 Substituted benzopyranopyridines Expired GB1481595A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58719775A 1975-06-13 1975-06-13

Publications (1)

Publication Number Publication Date
GB1481595A true GB1481595A (en) 1977-08-03

Family

ID=24348790

Family Applications (1)

Application Number Title Priority Date Filing Date
GB22953/76A Expired GB1481595A (en) 1975-06-13 1976-06-03 Substituted benzopyranopyridines

Country Status (11)

Country Link
JP (1) JPS527997A (en)
AU (1) AU1456176A (en)
BE (1) BE842901A (en)
DE (1) DE2623256A1 (en)
DK (1) DK244776A (en)
ES (1) ES448867A1 (en)
FR (1) FR2313931A1 (en)
GB (1) GB1481595A (en)
LU (1) LU75160A1 (en)
NL (1) NL7606371A (en)
SE (1) SE7606730L (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2411847A1 (en) * 1973-03-21 1974-10-10 Warner Lambert Co SUBSTITUTED BENZOPYRANO SQUARE CLIP ON 3.4-C SQUARE BRACKET FOR PYRIDINE AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Also Published As

Publication number Publication date
FR2313931B1 (en) 1978-10-20
ES448867A1 (en) 1977-08-01
AU1456176A (en) 1977-12-08
BE842901A (en) 1976-12-13
JPS527997A (en) 1977-01-21
SE7606730L (en) 1976-12-14
DK244776A (en) 1976-12-14
DE2623256A1 (en) 1976-12-30
NL7606371A (en) 1976-12-15
LU75160A1 (en) 1977-01-26
FR2313931A1 (en) 1977-01-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee