GB1480188A - Use of melt-sprayed spherical phenacetin granules for the production of tablets - Google Patents

Use of melt-sprayed spherical phenacetin granules for the production of tablets

Info

Publication number
GB1480188A
GB1480188A GB1392175A GB1392175A GB1480188A GB 1480188 A GB1480188 A GB 1480188A GB 1392175 A GB1392175 A GB 1392175A GB 1392175 A GB1392175 A GB 1392175A GB 1480188 A GB1480188 A GB 1480188A
Authority
GB
United Kingdom
Prior art keywords
phenacetin
granules
tablets
melt
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1392175A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1480188A publication Critical patent/GB1480188A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB1392175A 1974-04-06 1975-04-04 Use of melt-sprayed spherical phenacetin granules for the production of tablets Expired GB1480188A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742416903 DE2416903A1 (de) 1974-04-06 1974-04-06 Verwendung von schmelzverspruehtem kugelfoermigem phenacetingranulat zur herstellung von tabletten im direkttablettierverfahren

Publications (1)

Publication Number Publication Date
GB1480188A true GB1480188A (en) 1977-07-20

Family

ID=5912381

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1392175A Expired GB1480188A (en) 1974-04-06 1975-04-04 Use of melt-sprayed spherical phenacetin granules for the production of tablets

Country Status (8)

Country Link
BE (1) BE827560A (US06826419-20041130-M00005.png)
DE (1) DE2416903A1 (US06826419-20041130-M00005.png)
DK (1) DK136398C (US06826419-20041130-M00005.png)
FR (1) FR2274280A1 (US06826419-20041130-M00005.png)
GB (1) GB1480188A (US06826419-20041130-M00005.png)
IE (1) IE40907B1 (US06826419-20041130-M00005.png)
LU (1) LU72206A1 (US06826419-20041130-M00005.png)
NL (1) NL7504054A (US06826419-20041130-M00005.png)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124027A1 (en) * 1983-04-29 1984-11-07 FISONS CORPORATION (a Massachusetts corporation) Rapid dissolving, uniform drug compositions and their preparation
WO1992003126A1 (en) * 1990-08-24 1992-03-05 BIOGAL Gyógyszergyár Rt. Process for the preparation of a tablet or dragee composition containing a heat-, light- and moisture-sensitive active ingredient having monoclinic crystal structure
US5556639A (en) * 1991-01-30 1996-09-17 Glaxo Wellcome Inc. Water-dispersible tablets
EP0752848A1 (en) * 1995-01-09 1997-01-15 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
US5698221A (en) * 1992-07-27 1997-12-16 Patel; Suryakant Dahyabhai Water-dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5965166A (en) * 1995-11-15 1999-10-12 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034035A (en) * 1975-07-14 1977-07-05 Merck & Co., Inc. Method of preparing multi-toned tablets
FR2586561B1 (fr) * 1985-09-05 1988-05-20 Rhone Poulenc Sante Procede de preparation d'agglomerats spheriques de paracetamol et produits obtenus
EP0272265B1 (de) * 1985-09-25 1991-05-22 Gergely, Gerhard, Dr. Zerfallstablette und verfahren zu ihrer herstellung
US4710519A (en) * 1985-09-30 1987-12-01 Basf Corporation Process for preparing spray dried acetaminophen powder and the powder prepared thereby
DE3830749A1 (de) * 1987-09-11 1989-03-30 Squibb & Sons Inc Arzneimittel in form von kuegelchen mit hohem arzneistoffgehalt und verfahren zu ihrer herstellung

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
EP0124027A1 (en) * 1983-04-29 1984-11-07 FISONS CORPORATION (a Massachusetts corporation) Rapid dissolving, uniform drug compositions and their preparation
WO1992003126A1 (en) * 1990-08-24 1992-03-05 BIOGAL Gyógyszergyár Rt. Process for the preparation of a tablet or dragee composition containing a heat-, light- and moisture-sensitive active ingredient having monoclinic crystal structure
US5322698A (en) * 1990-08-24 1994-06-21 Biogal Gyogyszergyar Rt. Process for the preparation of a tablet or dragee composition containing a heat-, light- and moisture-sensitive active ingredient having monoclinic crystal structure
US5556639A (en) * 1991-01-30 1996-09-17 Glaxo Wellcome Inc. Water-dispersible tablets
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
US5660860A (en) * 1991-01-30 1997-08-26 Glaxo Wellcome Inc. Water-dispersible tablets
US5698221A (en) * 1992-07-27 1997-12-16 Patel; Suryakant Dahyabhai Water-dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
EP0752848A4 (en) * 1995-01-09 1998-11-04 Mendell Co Inc Edward PHARMACEUTICAL AUXILIARY SUBSTANCE WITH IMPROVED COMPRESSIBILITY
EP1287823A1 (en) * 1995-01-09 2003-03-05 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
EP0752848A1 (en) * 1995-01-09 1997-01-15 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6103219A (en) * 1995-01-09 2000-08-15 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6217909B1 (en) 1995-01-09 2001-04-17 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6358533B2 (en) 1995-01-09 2002-03-19 Edward Mendell, Co., Inc. Pharmaceutical excipient having improved compressibility
US6858231B2 (en) 1995-01-09 2005-02-22 J. Rettenmaier & Soehne Gmbh + Co. Kg Pharmaceutical excipient having improved compressibility
US6746693B2 (en) 1995-01-09 2004-06-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Pharmaceutical excipient having improved compressibility
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5965166A (en) * 1995-11-15 1999-10-12 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6217907B1 (en) 1995-11-15 2001-04-17 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6866867B2 (en) 1996-06-10 2005-03-15 J. Rettenmaier & Soehne Gmbh + Co. Kg Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose

Also Published As

Publication number Publication date
DE2416903A1 (de) 1975-10-09
BE827560A (fr) 1975-10-06
FR2274280A1 (fr) 1976-01-09
DK136398B (da) 1977-10-10
DK136398C (da) 1978-04-10
DK146175A (US06826419-20041130-M00005.png) 1975-10-07
IE40907B1 (en) 1979-09-12
IE40907L (en) 1975-10-06
LU72206A1 (US06826419-20041130-M00005.png) 1976-03-02
FR2274280B1 (US06826419-20041130-M00005.png) 1978-11-10
NL7504054A (nl) 1975-10-08

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee