GB1480038A - D-homosteroids - Google Patents
D-homosteroidsInfo
- Publication number
- GB1480038A GB1480038A GB40804/75A GB4080475A GB1480038A GB 1480038 A GB1480038 A GB 1480038A GB 40804/75 A GB40804/75 A GB 40804/75A GB 4080475 A GB4080475 A GB 4080475A GB 1480038 A GB1480038 A GB 1480038A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- homopregna
- dien
- hydroxy
- halogenation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000000795 D-homosteroids Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 13
- 238000005658 halogenation reaction Methods 0.000 abstract 4
- -1 3,3 - ethylenedioxy - Chemical class 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- 239000000543 intermediate Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 238000007069 methylation reaction Methods 0.000 abstract 2
- TUNMWZWFKFYHNV-UHFFFAOYSA-N 8-methoxy-12a-methyl-1,3,4,4a,4b,5,6,10b,11,12-decahydrochrysen-2-one Chemical compound C1CC2(C)CC(=O)CCC2C2C1C1=CC=C(OC)C=C1CC2 TUNMWZWFKFYHNV-UHFFFAOYSA-N 0.000 abstract 1
- 241000349731 Afzelia bipindensis Species 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 238000006345 epimerization reaction Methods 0.000 abstract 1
- 238000006735 epoxidation reaction Methods 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- IHLVCKWPAMTVTG-UHFFFAOYSA-N lithium;carbanide Chemical compound [Li+].[CH3-] IHLVCKWPAMTVTG-UHFFFAOYSA-N 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000005822 methylenation reaction Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 125000005490 tosylate group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1342474A CH606112A5 (en) | 1974-10-07 | 1974-10-07 | Hormonally active D-homosteroids |
| CH1595074 | 1974-12-02 | ||
| CH319575A CH617210A5 (en) | 1975-03-13 | 1975-03-13 | Process for the preparation of D-homosteroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1480038A true GB1480038A (en) | 1977-07-20 |
Family
ID=27174186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40804/75A Expired GB1480038A (en) | 1974-10-07 | 1975-10-06 | D-homosteroids |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4026922A (enExample) |
| JP (1) | JPS5163167A (enExample) |
| AR (2) | AR208565A1 (enExample) |
| AT (1) | AT349661B (enExample) |
| BE (1) | BE834214A (enExample) |
| CA (1) | CA1052767A (enExample) |
| DD (1) | DD123090A5 (enExample) |
| DE (1) | DE2544701C2 (enExample) |
| ES (3) | ES441522A1 (enExample) |
| FR (1) | FR2287218A1 (enExample) |
| GB (1) | GB1480038A (enExample) |
| HK (1) | HK40680A (enExample) |
| HU (1) | HU174008B (enExample) |
| IE (1) | IE42054B1 (enExample) |
| IL (1) | IL48158A (enExample) |
| KE (1) | KE3063A (enExample) |
| LU (1) | LU73527A1 (enExample) |
| NL (1) | NL7511760A (enExample) |
| NZ (1) | NZ178767A (enExample) |
| PH (1) | PH12296A (enExample) |
| SE (1) | SE411351B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4193940A (en) * | 1977-06-29 | 1980-03-18 | Hoffmann-La Roche Inc. | 14 β-Hydroxyandrostanes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2860158A (en) * | 1954-10-18 | 1958-11-11 | Sterling Drug Inc | Compounds of the perhydrochrysene series and preparation thereof |
| US3076023A (en) * | 1960-05-31 | 1963-01-29 | Schering Ag | Process for preparing d-homo steroids |
| US3644441A (en) * | 1969-11-17 | 1972-02-22 | Schering Ag | Method for the production of 21-fluoro-4 6-pregnadienes |
| CH571018A5 (enExample) * | 1972-03-29 | 1975-12-31 | Hoffmann La Roche |
-
1975
- 1975-03-21 SE SE7503303A patent/SE411351B/xx not_active IP Right Cessation
- 1975-09-23 IL IL48158A patent/IL48158A/xx unknown
- 1975-09-23 NZ NZ178767A patent/NZ178767A/xx unknown
- 1975-10-01 IE IE2149/75A patent/IE42054B1/en unknown
- 1975-10-02 US US05/619,065 patent/US4026922A/en not_active Expired - Lifetime
- 1975-10-03 FR FR7530350A patent/FR2287218A1/fr active Granted
- 1975-10-03 DD DD188721A patent/DD123090A5/xx unknown
- 1975-10-06 GB GB40804/75A patent/GB1480038A/en not_active Expired
- 1975-10-06 JP JP50119875A patent/JPS5163167A/ja active Granted
- 1975-10-06 BE BE160706A patent/BE834214A/xx not_active IP Right Cessation
- 1975-10-06 PH PH17632A patent/PH12296A/en unknown
- 1975-10-06 AT AT763375A patent/AT349661B/de not_active IP Right Cessation
- 1975-10-06 ES ES441522A patent/ES441522A1/es not_active Expired
- 1975-10-06 CA CA237,122A patent/CA1052767A/en not_active Expired
- 1975-10-06 DE DE2544701A patent/DE2544701C2/de not_active Expired
- 1975-10-06 LU LU73527A patent/LU73527A1/xx unknown
- 1975-10-06 HU HU75HO1841A patent/HU174008B/hu unknown
- 1975-10-07 AR AR260705A patent/AR208565A1/es active
- 1975-10-07 NL NL7511760A patent/NL7511760A/xx not_active Application Discontinuation
-
1976
- 1976-05-17 AR AR263306A patent/AR208787A1/es active
- 1976-09-07 ES ES451299A patent/ES451299A1/es not_active Expired
- 1976-09-07 ES ES451297A patent/ES451297A1/es not_active Expired
-
1980
- 1980-07-07 KE KE3063A patent/KE3063A/xx unknown
- 1980-08-07 HK HK406/80A patent/HK40680A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL48158A (en) | 1978-07-31 |
| NL7511760A (nl) | 1976-04-09 |
| FR2287218A1 (fr) | 1976-05-07 |
| ES451297A1 (es) | 1978-03-16 |
| BE834214A (fr) | 1976-04-06 |
| JPS5163167A (en) | 1976-06-01 |
| AT349661B (de) | 1979-04-25 |
| ES451299A1 (es) | 1977-12-01 |
| IE42054B1 (en) | 1980-05-21 |
| HU174008B (hu) | 1979-10-28 |
| SE411351B (sv) | 1979-12-17 |
| AU8522575A (en) | 1977-03-31 |
| DE2544701A1 (de) | 1976-04-15 |
| DE2544701C2 (de) | 1985-02-07 |
| US4026922A (en) | 1977-05-31 |
| CA1052767A (en) | 1979-04-17 |
| NZ178767A (en) | 1978-06-20 |
| IE42054L (en) | 1976-04-07 |
| SE7503303L (sv) | 1976-04-08 |
| FR2287218B1 (enExample) | 1980-05-30 |
| PH12296A (en) | 1978-12-29 |
| JPS611440B2 (enExample) | 1986-01-17 |
| ES441522A1 (es) | 1977-07-01 |
| AR208565A1 (es) | 1977-02-15 |
| IL48158A0 (en) | 1975-11-25 |
| LU73527A1 (enExample) | 1977-05-24 |
| ATA763375A (de) | 1978-09-15 |
| KE3063A (en) | 1980-07-25 |
| AR208787A1 (es) | 1977-02-28 |
| DD123090A5 (enExample) | 1976-11-20 |
| HK40680A (en) | 1980-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1475795A (en) | Steroid 21-thioesters | |
| GB1159490A (en) | Improvements in Acylated Steroids | |
| GB1494097A (en) | D-homo-20-keto-pregnanes | |
| GB1445945A (en) | Steroids of the d-homo-pregnane series | |
| GB1480038A (en) | D-homosteroids | |
| GB1365469A (en) | Steroids of the d-homopregnane series | |
| ES359268A1 (es) | Un procedimiento para la preparacion de 6 alfa, 6 beta-di- fluoresteroides. | |
| GB1508745A (en) | Steroidal(16alpha,17-d)cyclohexenes | |
| AU3406684A (en) | Estrane and androstane derivatives | |
| GB1147803A (en) | Improvements in or relating to novel steroids and the manufacture thereof | |
| GB1211836A (en) | Novel 15,16-alkylidene-steroids and a process for the manufacture thereof | |
| GB1530615A (en) | 15,16-methylene-steroids of the pregnane series | |
| IE38074L (en) | Delta 8(9)-steroids of the pregnane series. | |
| US2875200A (en) | 9alpha-halo-11beta, 21-dihydroxy-4, 17(20)-pregnadiene-3-one compounds and process of preparing thereof | |
| GB1430904A (en) | D-homopregnenes | |
| GB1416475A (en) | 21-orthoesters of cortical steroids and methods of preparing same | |
| IE32938L (en) | 17alpha,21-orthocarbonates of steroid-derivatives and¹process for preparing them | |
| GB1363460A (en) | Rofluoropregnenes | |
| SE7514455L (sv) | 13-etynylsteroider och sett att framstella sadana | |
| GB1504410A (en) | 11beta-fluoroandrostenes | |
| GB1272688A (en) | Sulphamido-steroids and the preparation thereof | |
| GB1367384A (en) | Steroids and a process for the manufacture thereof | |
| GB1324381A (en) | 9alpha-methyl steroids | |
| GB1428347A (en) | 6alpha-, 7alpha-dihydro-3h-cyclopropa-6,7-pregna-4,6-diene- 3,15,20-trione and related compound | |
| GB1198145A (en) | 2D-Hydroperoxy-delta<16>-Steroids of the Pregnane Series |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |