GB1474775A - Isoquinolines - Google Patents

Isoquinolines

Info

Publication number
GB1474775A
GB1474775A GB4290974A GB4290974A GB1474775A GB 1474775 A GB1474775 A GB 1474775A GB 4290974 A GB4290974 A GB 4290974A GB 4290974 A GB4290974 A GB 4290974A GB 1474775 A GB1474775 A GB 1474775A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
alkoxy
reacting
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4290974A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1474775A publication Critical patent/GB1474775A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB4290974A 1973-10-08 1974-10-03 Isoquinolines Expired GB1474775A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1430773A CH581113A5 (ru) 1973-10-08 1973-10-08

Publications (1)

Publication Number Publication Date
GB1474775A true GB1474775A (en) 1977-05-25

Family

ID=4399720

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4290974A Expired GB1474775A (en) 1973-10-08 1974-10-03 Isoquinolines

Country Status (21)

Country Link
JP (1) JPS5082078A (ru)
AT (1) ATA802974A (ru)
AU (2) AU498889B2 (ru)
BE (1) BE820789A (ru)
CA (1) CA1021772A (ru)
CH (1) CH581113A5 (ru)
DD (1) DD114605A5 (ru)
DE (1) DE2447756A1 (ru)
DK (1) DK135766B (ru)
ES (1) ES430759A1 (ru)
FI (1) FI286374A (ru)
FR (1) FR2247242B1 (ru)
GB (1) GB1474775A (ru)
HU (1) HU169126B (ru)
IL (1) IL45797A (ru)
NL (1) NL7413105A (ru)
NO (1) NO743534L (ru)
PH (1) PH11611A (ru)
SE (1) SE7412310L (ru)
SU (1) SU567403A3 (ru)
ZA (1) ZA746409B (ru)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2818290A1 (de) * 1977-05-02 1978-11-09 Merck & Co Inc Neue naphthyridine
WO1999011628A1 (en) * 1997-09-03 1999-03-11 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
US6306889B1 (en) 1997-09-03 2001-10-23 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6348475B1 (en) 2000-06-01 2002-02-19 Guilford Pharmaceuticals Inc. Methods, compounds and compositions for treating gout
US6387902B1 (en) 1998-12-31 2002-05-14 Guilford Pharmaceuticals, Inc. Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP
US6395749B1 (en) 1998-05-15 2002-05-28 Guilford Pharmaceuticals Inc. Carboxamide compounds, methods, and compositions for inhibiting PARP activity
US6426415B1 (en) 1997-09-03 2002-07-30 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity
US6514983B1 (en) 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6635642B1 (en) 1997-09-03 2003-10-21 Guilford Pharmaceuticals Inc. PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same
US6716828B1 (en) 1999-09-01 2004-04-06 Guilford Pharmaceuticals, Inc. Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
US6723733B2 (en) 2000-05-19 2004-04-20 Guilford Pharmaceuticals, Inc. Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK116976A (da) * 1975-03-26 1976-09-27 Sandoz Ag Fremgangsmade til fremstilling af isoquinolinderivater
US4129565A (en) * 1975-07-11 1978-12-12 Nisshin Flour Milling Co., Ltd. Isocarbostyril derivatives
EP0711804A3 (de) 1994-11-14 1999-09-22 Ciba SC Holding AG Kryptolichtschutzmittel

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2818290A1 (de) * 1977-05-02 1978-11-09 Merck & Co Inc Neue naphthyridine
US6380211B1 (en) 1997-09-03 2002-04-30 Guilford Pharmaceutical Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
AU752768B2 (en) * 1997-09-03 2002-09-26 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting parp activity
US6306889B1 (en) 1997-09-03 2001-10-23 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6346536B1 (en) 1997-09-03 2002-02-12 Guilford Pharmaceuticals Inc. Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same
US6635642B1 (en) 1997-09-03 2003-10-21 Guilford Pharmaceuticals Inc. PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same
WO1999011628A1 (en) * 1997-09-03 1999-03-11 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhi biting parp activity
US6514983B1 (en) 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6197785B1 (en) 1997-09-03 2001-03-06 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
US6426415B1 (en) 1997-09-03 2002-07-30 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity
US6395749B1 (en) 1998-05-15 2002-05-28 Guilford Pharmaceuticals Inc. Carboxamide compounds, methods, and compositions for inhibiting PARP activity
US6387902B1 (en) 1998-12-31 2002-05-14 Guilford Pharmaceuticals, Inc. Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP
US6716828B1 (en) 1999-09-01 2004-04-06 Guilford Pharmaceuticals, Inc. Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
US6723733B2 (en) 2000-05-19 2004-04-20 Guilford Pharmaceuticals, Inc. Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses
US6348475B1 (en) 2000-06-01 2002-02-19 Guilford Pharmaceuticals Inc. Methods, compounds and compositions for treating gout

Also Published As

Publication number Publication date
IL45797A0 (en) 1974-12-31
AU7409074A (en) 1976-04-15
AU7413074A (en) 1976-04-15
NL7413105A (nl) 1975-04-10
CA1021772A (en) 1977-11-29
SU567403A3 (ru) 1977-07-30
CH581113A5 (ru) 1976-10-29
HU169126B (ru) 1976-09-28
FR2247242B1 (ru) 1978-07-21
DD114605A5 (ru) 1975-08-12
AU7408974A (en) 1976-04-15
DE2447756A1 (de) 1975-04-10
BE820789A (fr) 1975-04-07
FR2247242A1 (ru) 1975-05-09
AU498889B2 (en) 1979-03-29
NO743534L (ru) 1975-05-05
FI286374A (ru) 1975-04-09
IL45797A (en) 1978-04-30
DK514874A (ru) 1975-06-09
ES430759A1 (es) 1977-04-16
ATA802974A (de) 1979-07-15
DK135766B (da) 1977-06-20
SE7412310L (ru) 1975-04-09
JPS5082078A (ru) 1975-07-03
ZA746409B (en) 1976-05-26
DK135766C (ru) 1977-11-21
PH11611A (en) 1978-04-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee