GB1471012A - Diphenyl ethers - Google Patents
Diphenyl ethersInfo
- Publication number
- GB1471012A GB1471012A GB3838574A GB3838574A GB1471012A GB 1471012 A GB1471012 A GB 1471012A GB 3838574 A GB3838574 A GB 3838574A GB 3838574 A GB3838574 A GB 3838574A GB 1471012 A GB1471012 A GB 1471012A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen atom
- hydrogen
- diphenyl ethers
- choh
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1471012 Diphenyl ethers SANDOZ Ltd 3 Sept 1974 [4 Sept 1973] 38385/74 Heading C2C Diphenyl ethers of the general formula wherein W is CO or CHOH, each of R and R 4 is a hydrogen, fluorine or chlorine atom or a C 1-4 alkyl group, R 1 is a branched C 3-5 alkyl group and each of R 2 and R 3 is a hydrogen, fluorine or chlorine atom or a C 1-4 alkyl or C 1-4 alkoxy group, which are novel provided that (i) when each of R, R 2 , R 3 and R 4 is a hydrogen atom, then R 1 is other than -C(CH 3 ) 3 , (ii) when each of R, R 2 , R 3 and R 4 is a hydrogen atom and W is CO, then R 1 is other than -CH(CH 3 ) 2 or -(CH 2 ) 2 CH(CH 3 ) 2 and (iii) when one of R 2 and R 3 is CH 3 O- in the 4- position and the other is a hydrogen atom, each of R and R 4 is a hydrogen atom and W is CO, then R 1 is other than -CH 2 CH(CH 3 ) 2 , are prepared (a) when W is CO, by hydrolysing the product of the rection between a 4-(R 2 , R 3 - phenoxy) - (R,R 4 - phenyl) - magnesium bromide and R 1 COCL or (b) when W is CHOH, by reducing the product of (a) in an inert organic solvent. Pharmaceutical compositions having hypolipidemic activity comprise, as active ingredient, a diphenyl ether of the general formula above, in association with a pharmaceutically acceptable diluent or carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39418173A | 1973-09-04 | 1973-09-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1471012A true GB1471012A (en) | 1977-04-21 |
Family
ID=23557898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3838574A Expired GB1471012A (en) | 1973-09-04 | 1974-09-03 | Diphenyl ethers |
Country Status (11)
Country | Link |
---|---|
BE (1) | BE819461A (en) |
CA (1) | CA1048934A (en) |
DE (1) | DE2442117A1 (en) |
FR (1) | FR2242078B1 (en) |
GB (1) | GB1471012A (en) |
HK (1) | HK43080A (en) |
IE (1) | IE39883B1 (en) |
IL (1) | IL45576A (en) |
MY (1) | MY8100141A (en) |
NL (1) | NL7411553A (en) |
ZA (1) | ZA745634B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0069597A1 (en) * | 1981-07-08 | 1983-01-12 | RAYCHEM CORPORATION (a California corporation) | Preparing p-phenoxy-benzoyl compounds |
EP0322983A1 (en) * | 1987-12-28 | 1989-07-05 | The Dow Chemical Company | Phenoxyphenoxypropionates, intermediates thereof and methods of preparation |
-
1974
- 1974-08-30 NL NL7411553A patent/NL7411553A/en not_active Application Discontinuation
- 1974-09-02 IE IE1810/74A patent/IE39883B1/en unknown
- 1974-09-02 IL IL45576A patent/IL45576A/en unknown
- 1974-09-02 BE BE148144A patent/BE819461A/en unknown
- 1974-09-03 CA CA74208322A patent/CA1048934A/en not_active Expired
- 1974-09-03 FR FR7429928A patent/FR2242078B1/fr not_active Expired
- 1974-09-03 DE DE2442117A patent/DE2442117A1/en not_active Ceased
- 1974-09-03 GB GB3838574A patent/GB1471012A/en not_active Expired
- 1974-09-04 ZA ZA00745634A patent/ZA745634B/en unknown
-
1980
- 1980-08-14 HK HK430/80A patent/HK43080A/en unknown
-
1981
- 1981-12-30 MY MY141/81A patent/MY8100141A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0069597A1 (en) * | 1981-07-08 | 1983-01-12 | RAYCHEM CORPORATION (a California corporation) | Preparing p-phenoxy-benzoyl compounds |
EP0322983A1 (en) * | 1987-12-28 | 1989-07-05 | The Dow Chemical Company | Phenoxyphenoxypropionates, intermediates thereof and methods of preparation |
Also Published As
Publication number | Publication date |
---|---|
IL45576A (en) | 1977-08-31 |
FR2242078A1 (en) | 1975-03-28 |
CA1048934A (en) | 1979-02-20 |
IE39883B1 (en) | 1979-01-17 |
DE2442117A1 (en) | 1975-03-06 |
IL45576A0 (en) | 1974-11-29 |
FR2242078B1 (en) | 1978-07-28 |
IE39883L (en) | 1975-03-04 |
ZA745634B (en) | 1976-04-28 |
HK43080A (en) | 1980-08-22 |
BE819461A (en) | 1975-03-03 |
NL7411553A (en) | 1975-03-06 |
MY8100141A (en) | 1981-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE34511L (en) | Piperazine ethers. | |
GB1413892A (en) | 2-pyrimidinyl-thio-acetic acids and their derivatives | |
GB1471012A (en) | Diphenyl ethers | |
GB1069747A (en) | Hexachlorocyclopentadiene-tetrahydrophthalic anhydride adduct and derivatives | |
GB1294720A (en) | Aryl butanol derivatives, compositions containing them, and processes for preparing aryl ketone derivatives from them | |
GB1467386A (en) | Manufacture of o-benzyltoluenes | |
GB1298386A (en) | Process for the preparation of tertiary phosphine oxides | |
GB1399325A (en) | Bicyclic compounds their use and process for preparing same | |
GB1116308A (en) | Novels-triazolo[3,4-a]isoquinolines and the preparation thereof | |
GB1109310A (en) | Heterocyclic ethanols | |
GB1436505A (en) | -omega-i-imidazolyl-alkyl-hydrogen monothiosulphates and salts thereof | |
GB1448357A (en) | Process for preparing dihydric phenol derivatives | |
GB1252487A (en) | ||
GB1445127A (en) | Benzocycloheptathiophene derivatives | |
GB1423017A (en) | Phosphorothionoamidate derivatives having plant growth regulating properties | |
GB1430188A (en) | Diaza-oxa-bicyclodecane derivatives | |
GB1416943A (en) | Alkyl-alkenyl ketones and their use in pest control | |
GB1497723A (en) | Octahydrobenzo-(c)(1,6)-naphthyridine derivative | |
GB1200981A (en) | Novel bis-p-chlorophenoxy-acetic acid esters, the preparation thereof and compositions containing the same | |
ES351413A1 (en) | 1-(pyridyl-2')-3-(methyl or ethyl)-3-methyl-1,2,3,4 - tetrahydro-isoquinolines and salts thereof | |
GB1346456A (en) | Organic acid 2,6-disubstituted phenyl hydrazides | |
GB1246305A (en) | Fluorine-containing esters | |
GB1158264A (en) | Substituted 1,2-Dihydroquinoline-N-Carboxylic Acids and -Thioncarboxylic Acids | |
GB1489783A (en) | Substituted keto-acids and esters and pharmaceutical uses thereof | |
GB1348291A (en) | Aralkyl compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |