GB1466924A - Indazole derivatives - Google Patents
Indazole derivativesInfo
- Publication number
- GB1466924A GB1466924A GB1464674A GB1464674A GB1466924A GB 1466924 A GB1466924 A GB 1466924A GB 1464674 A GB1464674 A GB 1464674A GB 1464674 A GB1464674 A GB 1464674A GB 1466924 A GB1466924 A GB 1466924A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- alkyl
- indazole
- produce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003453 indazolyl group Chemical class N1N=C(C2=C1C=CC=C2)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004455 (C1-C3) alkylthio group Chemical group 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- MDELYEBAXHZXLZ-UHFFFAOYSA-N 1h-indazol-4-amine Chemical class NC1=CC=CC2=C1C=NN2 MDELYEBAXHZXLZ-UHFFFAOYSA-N 0.000 abstract 1
- WVJBMVFJLARMGJ-UHFFFAOYSA-N 1h-indazol-4-ylcyanamide Chemical compound N#CNC1=CC=CC2=C1C=NN2 WVJBMVFJLARMGJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- ZVGCIMVMXFUSDB-UHFFFAOYSA-N 2-methyl-1-nitro-1-nitrosoguanidine Chemical compound CN=C(N)N(N=O)[N+]([O-])=O ZVGCIMVMXFUSDB-UHFFFAOYSA-N 0.000 abstract 1
- HNLMMCOMDHTWKG-UHFFFAOYSA-N 3-chloro-2h-indazol-4-amine Chemical compound NC1=CC=CC2=C1C(Cl)=NN2 HNLMMCOMDHTWKG-UHFFFAOYSA-N 0.000 abstract 1
- QQOZWCKZANRYNF-UHFFFAOYSA-N 3-chloro-4-isothiocyanato-2h-indazole Chemical compound C1=CC=C(N=C=S)C2=C(Cl)NN=C21 QQOZWCKZANRYNF-UHFFFAOYSA-N 0.000 abstract 1
- GUGAGLJJSMABRQ-UHFFFAOYSA-N 3-chloro-4-nitro-2h-indazole Chemical compound [O-][N+](=O)C1=CC=CC2=C1C(Cl)=NN2 GUGAGLJJSMABRQ-UHFFFAOYSA-N 0.000 abstract 1
- 101100516554 Caenorhabditis elegans nhr-5 gene Proteins 0.000 abstract 1
- GXGJIOMUZAGVEH-UHFFFAOYSA-N Chamazulene Chemical group CCC1=CC=C(C)C2=CC=C(C)C2=C1 GXGJIOMUZAGVEH-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
- ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH175976A CH579076A5 (enrdf_load_stackoverflow) | 1973-04-05 | 1973-04-05 | |
| CH491673A CH579075A5 (enrdf_load_stackoverflow) | 1973-04-05 | 1973-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1466924A true GB1466924A (en) | 1977-03-09 |
Family
ID=25688581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1464674A Expired GB1466924A (en) | 1973-04-05 | 1974-04-02 | Indazole derivatives |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5735717B2 (enrdf_load_stackoverflow) |
| BE (1) | BE813259A (enrdf_load_stackoverflow) |
| CA (1) | CA1027127A (enrdf_load_stackoverflow) |
| CH (2) | CH579075A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2416024A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2224156B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1466924A (enrdf_load_stackoverflow) |
| NL (1) | NL7404376A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2361425A (en) * | 2000-04-17 | 2001-10-24 | Sorex Ltd | Thiourea rodenticide |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57501378A (enrdf_load_stackoverflow) * | 1980-09-05 | 1982-08-05 | ||
| JPS6115015U (ja) * | 1984-07-02 | 1986-01-28 | 井上エムテ−ピ−株式会社 | フイルタ− |
| DE19653162C1 (de) | 1996-12-19 | 1998-05-20 | Goodwell Int Ltd | Snowboardbindung |
-
1973
- 1973-04-05 CH CH491673A patent/CH579075A5/xx not_active IP Right Cessation
- 1973-04-05 CH CH175976A patent/CH579076A5/xx not_active IP Right Cessation
-
1974
- 1974-03-19 CA CA195,358A patent/CA1027127A/en not_active Expired
- 1974-04-01 NL NL7404376A patent/NL7404376A/xx not_active Application Discontinuation
- 1974-04-02 GB GB1464674A patent/GB1466924A/en not_active Expired
- 1974-04-02 DE DE2416024A patent/DE2416024A1/de not_active Withdrawn
- 1974-04-03 JP JP3703674A patent/JPS5735717B2/ja not_active Expired
- 1974-04-03 BE BE142817A patent/BE813259A/xx not_active IP Right Cessation
- 1974-04-03 FR FR7411805A patent/FR2224156B1/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2361425A (en) * | 2000-04-17 | 2001-10-24 | Sorex Ltd | Thiourea rodenticide |
| GB2361425B (en) * | 2000-04-17 | 2004-03-31 | Sorex Ltd | Rodenticidal thiourea compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2416024A1 (de) | 1974-10-24 |
| CA1027127A (en) | 1978-02-28 |
| AU6761074A (en) | 1975-10-09 |
| CH579075A5 (enrdf_load_stackoverflow) | 1976-08-31 |
| JPS5735717B2 (enrdf_load_stackoverflow) | 1982-07-30 |
| FR2224156B1 (enrdf_load_stackoverflow) | 1978-07-28 |
| BE813259A (fr) | 1974-10-03 |
| NL7404376A (enrdf_load_stackoverflow) | 1974-10-08 |
| CH579076A5 (enrdf_load_stackoverflow) | 1976-08-31 |
| JPS49127971A (enrdf_load_stackoverflow) | 1974-12-07 |
| FR2224156A1 (enrdf_load_stackoverflow) | 1974-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |