GB1465392A - Process for obtaining solasodine and glycosides thereof - Google Patents
Process for obtaining solasodine and glycosides thereofInfo
- Publication number
- GB1465392A GB1465392A GB613774A GB613774A GB1465392A GB 1465392 A GB1465392 A GB 1465392A GB 613774 A GB613774 A GB 613774A GB 613774 A GB613774 A GB 613774A GB 1465392 A GB1465392 A GB 1465392A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solasodine
- glycosides
- solution
- feb
- centrifugation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Abstract
1465392 Solasodine and glycosides thereof ESCUELA POLITECNICA NACIONAL 11 Feb 1974 [9 Feb 1973] 06137/74 Heading C2U The invention comprises a process for preparing a solution of a solasodine glycoside (e.g. solasonine or solamargine) from an aqueousalcoholic extract of a fruit containing the glycoside, by removing a major part (preferably all) of the alcohol from the extract (e.g. by distillation) and precipitating impurities (e.g. by adding or distilling off water and/or cooling) which may be removed by filtration or centrifugation. The glycosides may be precipitated from the resultant solution by adding aq. ammonia or aq. sodium hydroxide. The fruit may be of a plant of the stellate Lepstostemonum group, e.g. "huapag" or "tree solanum", and may be fresh or dried, and cut or broken provided that rupture of the seeds is minimized. The extractant may comprise MeOH, EtOH or i-PrOH. Solasodine is prepared from the obtained glycosides (or the above purified solution thereof) by acidolysis (e.g. with HCl) in aqueous isopropanol, precipitation of the product (e.g. by adding sodium or potassium hydroxide or carbonate) and isolation (e.g. by filtration or centrifugation).
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33100473A | 1973-02-09 | 1973-02-09 | |
| CA196,612A CA1029010A (en) | 1973-02-09 | 1974-04-02 | Process for recovering and isolating solasodine |
| NL7404924A NL7404924A (en) | 1973-02-09 | 1974-04-10 | PROCEDURE FOR WINNING AND SEPARATION OF SOLASODINE. |
| CH523874A CH608245A5 (en) | 1973-02-09 | 1974-04-16 | Process for obtaining and isolating solasodine |
| JP49043219A JPS50135209A (en) | 1973-02-09 | 1974-04-17 | |
| DD178080A DD113753A5 (en) | 1973-02-09 | 1974-04-23 | |
| BR4139/74A BR7404139A (en) | 1973-02-09 | 1974-05-21 | PROCESS TO RECOVER AND ISOLATE SOLASODINE |
| FR7424352A FR2277820A1 (en) | 1973-02-09 | 1974-07-12 | SOLASODINE EXTRACTION AND SEPARATION PROCESS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1465392A true GB1465392A (en) | 1977-02-23 |
Family
ID=27570189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB613774A Expired GB1465392A (en) | 1973-02-09 | 1974-02-11 | Process for obtaining solasodine and glycosides thereof |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS50135209A (en) |
| BE (1) | BE814177A (en) |
| BR (1) | BR7404139A (en) |
| CA (1) | CA1029010A (en) |
| CH (1) | CH608245A5 (en) |
| DD (1) | DD113753A5 (en) |
| FR (1) | FR2277820A1 (en) |
| GB (1) | GB1465392A (en) |
| NL (1) | NL7404924A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5259997A (en) * | 1975-11-12 | 1977-05-17 | Nippon Keibi Hosho Kk | Chemical fire extinguishing method |
| JPS5259996A (en) * | 1975-11-12 | 1977-05-17 | Nippon Keibi Hosho Kk | Chemical fire extinguishing method |
-
1974
- 1974-02-11 GB GB613774A patent/GB1465392A/en not_active Expired
- 1974-04-02 CA CA196,612A patent/CA1029010A/en not_active Expired
- 1974-04-10 NL NL7404924A patent/NL7404924A/en not_active Application Discontinuation
- 1974-04-16 CH CH523874A patent/CH608245A5/en not_active IP Right Cessation
- 1974-04-17 JP JP49043219A patent/JPS50135209A/ja active Pending
- 1974-04-23 DD DD178080A patent/DD113753A5/xx unknown
- 1974-04-25 BE BE143603A patent/BE814177A/en unknown
- 1974-05-21 BR BR4139/74A patent/BR7404139A/en unknown
- 1974-07-12 FR FR7424352A patent/FR2277820A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DD113753A5 (en) | 1975-06-20 |
| FR2277820B3 (en) | 1977-05-06 |
| BE814177A (en) | 1974-10-25 |
| JPS50135209A (en) | 1975-10-27 |
| CH608245A5 (en) | 1978-12-29 |
| CA1029010A (en) | 1978-04-04 |
| FR2277820A1 (en) | 1976-02-06 |
| BR7404139A (en) | 1976-02-03 |
| AU6538574A (en) | 1975-08-14 |
| NL7404924A (en) | 1975-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3240775A (en) | Preparation of alpha-l-fucosides and l-fucose from fucoidan | |
| ATE19851T1 (en) | EXTRACTION PROCESS. | |
| US2301787A (en) | Recovery of saponin | |
| GB1465392A (en) | Process for obtaining solasodine and glycosides thereof | |
| GB1430885A (en) | Process for preparing a purified extract of quillaia bark | |
| US2730536A (en) | Recovery of ergosterol | |
| GB1135528A (en) | Improvements in the treatment of senna pods | |
| US2406840A (en) | Method of preparing pectase | |
| Haas et al. | The occurrence of sugar alcohols in marine algae: Sorbitol | |
| GB486898A (en) | Manufacture of substances resembling vitamines from plants | |
| GB1141573A (en) | A process of producing a new substance suitable for stimulating the function of the reticulo-endothelial system | |
| GB1280729A (en) | Process of recovering ammonium sulphate from an aqueous solution containing ammonium sulphate and methionine | |
| US2864745A (en) | Glaucarubin amebicide | |
| GB579459A (en) | Process for the purification of 4-hydroxycoumarins | |
| US3164581A (en) | Method for deriving glycyrrhiric production | |
| Murti et al. | Occurrence of free butein and butin in the flowers of Butea frondosa | |
| US4799966A (en) | Process for converting alpha to beta-lactose | |
| US1235198A (en) | Highly active vitamin preparation thoroughly freed from inactive ingredients. | |
| US3057878A (en) | Process for making crystalline potassium salt of gibberellic acid | |
| GB1378278A (en) | Total saponin extracts from panax ginseng c a meyer and process for the production thereof | |
| GB1453063A (en) | Method for purifying 3,5-cyclic-adenylic acid or 3,5-cyclic- deoxy-adenylic acid | |
| SU1175483A1 (en) | Method of obtaining flavones | |
| SU422731A1 (en) | METHOD OF OBTAINING GOLBANIC ACID | |
| US1902408A (en) | Manufacture of new cardio-active glucosides of bulbus scille | |
| SU1227199A1 (en) | Method of producing pustulan |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 49R | Reference inserted (sect. 9/1949) | ||
| SP | Amendment (slips) printed | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |