GB1458186A - Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them - Google Patents

Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them

Info

Publication number
GB1458186A
GB1458186A GB4143472A GB4143472A GB1458186A GB 1458186 A GB1458186 A GB 1458186A GB 4143472 A GB4143472 A GB 4143472A GB 4143472 A GB4143472 A GB 4143472A GB 1458186 A GB1458186 A GB 1458186A
Authority
GB
United Kingdom
Prior art keywords
compounds
sulphur
oxides
preparation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4143472A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB4143472A priority Critical patent/GB1458186A/en
Priority to ES418492A priority patent/ES418492A1/en
Priority to ZA00737107A priority patent/ZA737107B/en
Priority to IL43161A priority patent/IL43161A/en
Priority to AU60037/73A priority patent/AU488565B2/en
Priority to HU73WE00000496A priority patent/HU172109B/en
Priority to DE19732344800 priority patent/DE2344800A1/en
Priority to CA180,430A priority patent/CA1027953A/en
Priority to BE135399A priority patent/BE804555A/en
Priority to NL7312252A priority patent/NL7312252A/xx
Priority to FR7332119A priority patent/FR2199469B1/fr
Priority to IE1591/73A priority patent/IE39567B1/en
Priority to CH1282673A priority patent/CH617432A5/en
Priority to JP48100726A priority patent/JPS4992062A/ja
Priority to US05/619,175 priority patent/US4091108A/en
Priority to FR7600806A priority patent/FR2289183A1/en
Publication of GB1458186A publication Critical patent/GB1458186A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • C07D327/08—[b,e]-condensed with two six-membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76—Dibenzothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings

Abstract

Tricyclic compounds of the formula 1, in which the radicals Z<1>, Z<2> and Z<3> have the meaning given in Patent Claim 1, are obtained by oxidising compounds of the formula 2, in which Z<1'> denotes an acyl group derived from a carboxylic acid or Z<1>, in the 10-position and simultaneously oxidising an acyl group Z<1'> which may be present to the carboxyl group. The compounds are optionally converted into their salts or, if at least one of these substituents Z<1> and Z<2> is a carboxyl group, into their esters or amides by esterification or amidation. In mammals, the compounds act as inhibitors of certain allergic reactions. Several of the compounds of the formula 1 prepared are novel. <IMAGE>
GB4143472A 1972-09-06 1972-09-06 Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them Expired GB1458186A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GB4143472A GB1458186A (en) 1972-09-06 1972-09-06 Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them
ES418492A ES418492A1 (en) 1972-09-06 1973-09-05 Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them
ZA00737107A ZA737107B (en) 1972-09-06 1973-09-05 Sulphide compounds
IL43161A IL43161A (en) 1972-09-06 1973-09-05 Pharmaceutical compositions containing tricyclic sulfoxide compound, certain such novel compounds and their preparation
AU60037/73A AU488565B2 (en) 1973-09-05 Sulphide compounds
HU73WE00000496A HU172109B (en) 1972-09-06 1973-09-05 Process for producing tricyclic sulfoxide derivatives and pharmaceutical compositions containing them as active agents
DE19732344800 DE2344800A1 (en) 1972-09-06 1973-09-05 SULFUR-CONTAINING TRICYCLIC COMPOUNDS AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
CA180,430A CA1027953A (en) 1972-09-06 1973-09-06 Sulphide compounds
BE135399A BE804555A (en) 1972-09-06 1973-09-06 SULPHIDE COMPOUNDS
NL7312252A NL7312252A (en) 1972-09-06 1973-09-06
FR7332119A FR2199469B1 (en) 1972-09-06 1973-09-06
IE1591/73A IE39567B1 (en) 1972-09-06 1973-09-06 Oxides of sulphur-containing triclic compounds methods fortheir preparation and compositions containing them
CH1282673A CH617432A5 (en) 1972-09-06 1973-09-06 Process for the preparation of sulphur-containing heterotricyclic compounds
JP48100726A JPS4992062A (en) 1972-09-06 1973-09-06
US05/619,175 US4091108A (en) 1972-09-06 1975-10-03 Antiallergic pharmaceutical composition and use
FR7600806A FR2289183A1 (en) 1972-09-06 1976-01-14 MEDICINAL PRODUCT CONTAINING A THIOXANTHENE S-OXIDE OR PHENOXATHIINE DERIVATIVE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4143472A GB1458186A (en) 1972-09-06 1972-09-06 Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them
GB3895173 1973-08-17

Publications (1)

Publication Number Publication Date
GB1458186A true GB1458186A (en) 1976-12-08

Family

ID=26263961

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4143472A Expired GB1458186A (en) 1972-09-06 1972-09-06 Oxides of sulphur-containing tricyclic compounds methods for their preparation and compositions containing them

Country Status (10)

Country Link
JP (1) JPS4992062A (en)
CA (1) CA1027953A (en)
CH (1) CH617432A5 (en)
DE (1) DE2344800A1 (en)
ES (1) ES418492A1 (en)
FR (2) FR2199469B1 (en)
GB (1) GB1458186A (en)
IE (1) IE39567B1 (en)
IL (1) IL43161A (en)
NL (1) NL7312252A (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642997A (en) * 1969-06-25 1972-02-15 Merck & Co Inc Tricyclic carboxylic acids in the treatment of inflammation
NL7008628A (en) * 1969-06-25 1970-12-29
BE793954A (en) * 1972-07-19 1973-07-12 Syntex Corp THIOXANTHONE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES

Also Published As

Publication number Publication date
IL43161A0 (en) 1973-11-28
IL43161A (en) 1978-07-31
ES418492A1 (en) 1976-07-16
FR2199469A1 (en) 1974-04-12
CA1027953A (en) 1978-03-14
IE39567B1 (en) 1978-11-08
NL7312252A (en) 1974-03-08
IE39567L (en) 1974-03-06
FR2289183A1 (en) 1976-05-28
FR2199469B1 (en) 1977-01-28
CH617432A5 (en) 1980-05-30
FR2289183B1 (en) 1978-08-18
JPS4992062A (en) 1974-09-03
DE2344800A1 (en) 1974-03-21

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee