GB1457005A - 2-substituted-3-aminoquinoxalines - Google Patents
2-substituted-3-aminoquinoxalinesInfo
- Publication number
- GB1457005A GB1457005A GB5293673A GB5293673A GB1457005A GB 1457005 A GB1457005 A GB 1457005A GB 5293673 A GB5293673 A GB 5293673A GB 5293673 A GB5293673 A GB 5293673A GB 1457005 A GB1457005 A GB 1457005A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- compounds
- piperazino
- nrr
- hydroxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2-substituted-3-aminoquinoxalines Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- ALHUXMDEZNLFTA-UHFFFAOYSA-N methyl-quinoxaline Natural products C1=CC=CC2=NC(C)=CN=C21 ALHUXMDEZNLFTA-UHFFFAOYSA-N 0.000 abstract 2
- BYHVGQHIAFURIL-UHFFFAOYSA-N 2-chloroquinoxaline Chemical compound C1=CC=CC2=NC(Cl)=CN=C21 BYHVGQHIAFURIL-UHFFFAOYSA-N 0.000 abstract 1
- XTWJWLYIZBKWSW-UHFFFAOYSA-N 3-ethenylquinoxalin-2-amine Chemical class NC1=NC2=CC=CC=C2N=C1C=C XTWJWLYIZBKWSW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- XSCHRSMBECNVNS-UHFFFAOYSA-N benzopyrazine Natural products N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30816872A | 1972-11-20 | 1972-11-20 | |
| US41021473A | 1973-10-26 | 1973-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1457005A true GB1457005A (en) | 1976-12-01 |
Family
ID=26976126
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5293673A Expired GB1457005A (en) | 1972-11-20 | 1973-11-14 | 2-substituted-3-aminoquinoxalines |
| GB3198676A Expired GB1457400A (en) | 1972-11-20 | 1973-11-14 | Pharmaceutical compositions containing 2-substituted quinoxa lines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3198676A Expired GB1457400A (en) | 1972-11-20 | 1973-11-14 | Pharmaceutical compositions containing 2-substituted quinoxa lines |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS554100B2 (cs) |
| DE (1) | DE2357186A1 (cs) |
| FR (1) | FR2206951B1 (cs) |
| GB (2) | GB1457005A (cs) |
| NL (1) | NL7315808A (cs) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| WO2004000830A1 (en) | 2002-06-19 | 2003-12-31 | Biovitrum Ab | Novel compounds, their use and preparation |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI193974A7 (cs) * | 1973-07-13 | 1975-01-14 | Merck & Co Inc | |
| DE2730644A1 (de) * | 1977-07-07 | 1979-01-25 | Bayer Ag | Fluoreszenz-farbstoffe |
| WO1999042461A1 (en) * | 1998-02-23 | 1999-08-26 | Warner-Lambert Company | Substituted quinoxaline derivatives as interleukin-8 receptor antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2107301A1 (de) * | 1970-02-25 | 1971-09-09 | CIBA Geigy AG, Basel (Schweiz) | Neue heterocyclische Verbindungen und Verfahren zu ihrer Herstellung |
-
1973
- 1973-11-14 GB GB5293673A patent/GB1457005A/en not_active Expired
- 1973-11-14 GB GB3198676A patent/GB1457400A/en not_active Expired
- 1973-11-16 JP JP12836473A patent/JPS554100B2/ja not_active Expired
- 1973-11-16 DE DE2357186A patent/DE2357186A1/de active Pending
- 1973-11-19 NL NL7315808A patent/NL7315808A/xx not_active Application Discontinuation
- 1973-11-20 FR FR7341265A patent/FR2206951B1/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| US7071180B2 (en) | 1999-05-21 | 2006-07-04 | Biovitrum Ab | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| US7534794B2 (en) | 1999-05-21 | 2009-05-19 | Biovitrum Ab | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| WO2004000830A1 (en) | 2002-06-19 | 2003-12-31 | Biovitrum Ab | Novel compounds, their use and preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS49133384A (cs) | 1974-12-21 |
| DE2357186A1 (de) | 1974-05-22 |
| JPS554100B2 (cs) | 1980-01-29 |
| GB1457400A (en) | 1976-12-01 |
| FR2206951B1 (cs) | 1976-10-22 |
| NL7315808A (cs) | 1974-05-22 |
| FR2206951A1 (cs) | 1974-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |