GB1454361A - 1-substituted 4- beta-2-quinolyl-ethyl-piperazines and 1,2,3,4,tetrahydroquinoline analgoues thereof - Google Patents
1-substituted 4- beta-2-quinolyl-ethyl-piperazines and 1,2,3,4,tetrahydroquinoline analgoues thereofInfo
- Publication number
- GB1454361A GB1454361A GB1958274A GB1958274A GB1454361A GB 1454361 A GB1454361 A GB 1454361A GB 1958274 A GB1958274 A GB 1958274A GB 1958274 A GB1958274 A GB 1958274A GB 1454361 A GB1454361 A GB 1454361A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydroquinoline
- substituted
- alkyl
- analgoues
- piperazines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1454361 1 - Substituted - 4 - (# - 2 - quinolylethyl)pipazines and 1,2,3,4-tetrahydroquinoline analogues thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 3 May 1974 19582/74 Heading C2C Novel compounds of the Formula I and their 1,2,3,4-tetrahydroquinoline analogues wherein R is C 1-8 alkyl, phenyl optionally substituted with one or more alkyl, alkoxy, halo or trihalo alkyl groups, phenethyl or benzyl and non-toxic addition and quaternary ammonium salts thereof may be prepared by reacting 2-vinylquinoline with an R substituted piperazine in the presence of C 1-8 aliphatic carboxylic acid optionally followed by hydrogenation of the quinoline to 1,2,3,4-tetrahydroquinoline. Pharmaceutical compositions of the compounds I show hypotensive activity when administered parenterally with the usual excipients.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1958274A GB1454361A (en) | 1974-05-03 | 1974-05-03 | 1-substituted 4- beta-2-quinolyl-ethyl-piperazines and 1,2,3,4,tetrahydroquinoline analgoues thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1958274A GB1454361A (en) | 1974-05-03 | 1974-05-03 | 1-substituted 4- beta-2-quinolyl-ethyl-piperazines and 1,2,3,4,tetrahydroquinoline analgoues thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1454361A true GB1454361A (en) | 1976-11-03 |
Family
ID=10131792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1958274A Expired GB1454361A (en) | 1974-05-03 | 1974-05-03 | 1-substituted 4- beta-2-quinolyl-ethyl-piperazines and 1,2,3,4,tetrahydroquinoline analgoues thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1454361A (en) |
-
1974
- 1974-05-03 GB GB1958274A patent/GB1454361A/en not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |