GB1451478A - Phenylguanidine derivatives and processes for their preparation - Google Patents

Phenylguanidine derivatives and processes for their preparation

Info

Publication number
GB1451478A
GB1451478A GB3221175A GB3221175A GB1451478A GB 1451478 A GB1451478 A GB 1451478A GB 3221175 A GB3221175 A GB 3221175A GB 3221175 A GB3221175 A GB 3221175A GB 1451478 A GB1451478 A GB 1451478A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
halogen atom
processes
preparation
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3221175A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William H Rorer Inc
Original Assignee
William H Rorer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William H Rorer Inc filed Critical William H Rorer Inc
Publication of GB1451478A publication Critical patent/GB1451478A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB3221175A 1972-09-22 1973-09-24 Phenylguanidine derivatives and processes for their preparation Expired GB1451478A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29147472A 1972-09-22 1972-09-22

Publications (1)

Publication Number Publication Date
GB1451478A true GB1451478A (en) 1976-10-06

Family

ID=23120445

Family Applications (5)

Application Number Title Priority Date Filing Date
GB4465473A Expired GB1451477A (en) 1972-09-22 1973-09-24 Phenylamidinourea derivatives processes for their preparation and compositions incorporating them
GB3221175A Expired GB1451478A (en) 1972-09-22 1973-09-24 Phenylguanidine derivatives and processes for their preparation
GB2499276A Expired GB1451480A (en) 1972-09-22 1973-09-24 Processes for the preparation os substituted phenylguanidines and the compounds thus prepared
GB2491476A Expired GB1451479A (en) 1972-09-22 1973-09-24 Phenylamidourea derivatives and processes for their preparation
GB23574/75A Expired GB1514198A (en) 1972-09-22 1975-05-30 Substituted phenylguanidine compounds processes for their preparation and pharmaceutical compositions containing the same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB4465473A Expired GB1451477A (en) 1972-09-22 1973-09-24 Phenylamidinourea derivatives processes for their preparation and compositions incorporating them

Family Applications After (3)

Application Number Title Priority Date Filing Date
GB2499276A Expired GB1451480A (en) 1972-09-22 1973-09-24 Processes for the preparation os substituted phenylguanidines and the compounds thus prepared
GB2491476A Expired GB1451479A (en) 1972-09-22 1973-09-24 Phenylamidourea derivatives and processes for their preparation
GB23574/75A Expired GB1514198A (en) 1972-09-22 1975-05-30 Substituted phenylguanidine compounds processes for their preparation and pharmaceutical compositions containing the same

Country Status (14)

Country Link
JP (1) JPS593471B2 (es)
AR (1) AR200024A1 (es)
BE (1) BE805138A (es)
CA (1) CA1041908A (es)
CH (2) CH605703A5 (es)
DE (1) DE2345951C2 (es)
ES (1) ES418987A1 (es)
FR (1) FR2200002B1 (es)
GB (5) GB1451477A (es)
IL (1) IL43280A (es)
NL (1) NL7313040A (es)
PH (1) PH12016A (es)
SE (2) SE416952B (es)
ZA (1) ZA737475B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025652A (en) * 1975-03-31 1977-05-24 William H. Rorer, Inc. Amidinoureas
US4488993A (en) * 1972-09-22 1984-12-18 William H. Rorer, Inc. Amidinoureas
US4220658A (en) * 1972-09-22 1980-09-02 William H. Rorer, Inc. Treatment of hypertension with amidinoureas
US4326074A (en) 1972-09-22 1982-04-20 William H. Rorer, Inc. Amidinoureas
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
EP0612723B1 (de) * 1993-02-20 1997-08-27 Hoechst Aktiengesellschaft Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
FR2200002A1 (es) 1974-04-19
DE2345951C2 (de) 1986-10-23
SE416952B (sv) 1981-02-16
BE805138A (fr) 1974-01-16
AU6047973A (en) 1975-03-20
GB1514198A (en) 1978-06-14
JPS4985046A (es) 1974-08-15
ES418987A1 (es) 1976-07-01
CA1041908A (en) 1978-11-07
GB1451480A (en) 1976-10-06
DE2345951A1 (de) 1974-04-04
ZA737475B (en) 1974-10-30
PH12016A (en) 1978-10-06
SE7612176L (sv) 1976-11-02
JPS593471B2 (ja) 1984-01-24
FR2200002B1 (es) 1977-07-15
CH605703A5 (es) 1978-10-13
SE416953B (sv) 1981-02-16
IL43280A0 (en) 1973-11-28
GB1451477A (en) 1976-10-06
NL7313040A (es) 1974-03-26
AR200024A1 (es) 1974-10-15
GB1451479A (en) 1976-10-06
CH614430A5 (en) 1979-11-30
IL43280A (en) 1977-06-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee