GB1442772A - Inhibition of leukaemia utilizing 5-methyl-tetrahydrohomofolate - Google Patents

Inhibition of leukaemia utilizing 5-methyl-tetrahydrohomofolate

Info

Publication number
GB1442772A
GB1442772A GB3252873A GB3252873A GB1442772A GB 1442772 A GB1442772 A GB 1442772A GB 3252873 A GB3252873 A GB 3252873A GB 3252873 A GB3252873 A GB 3252873A GB 1442772 A GB1442772 A GB 1442772A
Authority
GB
United Kingdom
Prior art keywords
leukaemia
tetrahydrohomofolate
inhibition
utilizing
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3252873A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Us Health Education & Welfare
Original Assignee
Us Health Education & Welfare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health Education & Welfare filed Critical Us Health Education & Welfare
Publication of GB1442772A publication Critical patent/GB1442772A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB3252873A 1972-07-24 1973-07-09 Inhibition of leukaemia utilizing 5-methyl-tetrahydrohomofolate Expired GB1442772A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00274749A US3856959A (en) 1972-07-24 1972-07-24 Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Publications (1)

Publication Number Publication Date
GB1442772A true GB1442772A (en) 1976-07-14

Family

ID=23049461

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3252873A Expired GB1442772A (en) 1972-07-24 1973-07-09 Inhibition of leukaemia utilizing 5-methyl-tetrahydrohomofolate

Country Status (11)

Country Link
US (1) US3856959A (US20110158925A1-20110630-C00042.png)
JP (1) JPS5541207B2 (US20110158925A1-20110630-C00042.png)
AT (1) AT329312B (US20110158925A1-20110630-C00042.png)
AU (1) AU476551B2 (US20110158925A1-20110630-C00042.png)
BE (1) BE802709A (US20110158925A1-20110630-C00042.png)
CA (1) CA1006093A (US20110158925A1-20110630-C00042.png)
DE (1) DE2335898A1 (US20110158925A1-20110630-C00042.png)
FR (1) FR2193608B1 (US20110158925A1-20110630-C00042.png)
GB (1) GB1442772A (US20110158925A1-20110630-C00042.png)
NL (1) NL7309977A (US20110158925A1-20110630-C00042.png)
SE (1) SE431612B (US20110158925A1-20110630-C00042.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572137A (en) * 1977-02-22 1980-07-23 Bioresearch Sas Del Dr Livio C Stable compositions for therapeutic use based on d,1-5-methyltetrahydrofolic acid and its salts
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US9265746B2 (en) * 2006-05-31 2016-02-23 Merck & Cie Method for cell-specific targeting

Also Published As

Publication number Publication date
AT329312B (de) 1976-05-10
NL7309977A (US20110158925A1-20110630-C00042.png) 1974-01-28
AU476551B2 (en) 1976-09-30
FR2193608A1 (US20110158925A1-20110630-C00042.png) 1974-02-22
SE431612B (sv) 1984-02-20
JPS4950113A (US20110158925A1-20110630-C00042.png) 1974-05-15
ATA633073A (de) 1975-07-15
DE2335898A1 (de) 1974-02-07
CA1006093A (en) 1977-03-01
US3856959A (en) 1974-12-24
JPS5541207B2 (US20110158925A1-20110630-C00042.png) 1980-10-22
BE802709A (fr) 1973-11-16
AU5782073A (en) 1975-01-09
FR2193608B1 (US20110158925A1-20110630-C00042.png) 1976-08-13

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee