GB1437939A - Alpha-aryl-4-substituted piperidinoalkanol derivatives - Google Patents
Alpha-aryl-4-substituted piperidinoalkanol derivativesInfo
- Publication number
- GB1437939A GB1437939A GB339375A GB339375A GB1437939A GB 1437939 A GB1437939 A GB 1437939A GB 339375 A GB339375 A GB 339375A GB 339375 A GB339375 A GB 339375A GB 1437939 A GB1437939 A GB 1437939A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- alkyl
- substituted
- compounds
- naphthyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- -1 pyrrolidino piperidino, morpholino Chemical group 0.000 abstract 2
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000009434 installation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/440,855 US3941795A (en) | 1974-02-08 | 1974-02-08 | α-ARYL-4-SUBSTITUTED PIPERIDINOALKANOL DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1437939A true GB1437939A (en) | 1976-06-03 |
Family
ID=23750454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB339375A Expired GB1437939A (en) | 1974-02-08 | 1975-01-27 | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3941795A (en, 2012) |
| JP (1) | JPS50108266A (en, 2012) |
| BE (1) | BE825302R (en, 2012) |
| CA (1) | CA1082703A (en, 2012) |
| CH (1) | CH609972A5 (en, 2012) |
| DE (1) | DE2503362A1 (en, 2012) |
| DK (1) | DK41775A (en, 2012) |
| FR (1) | FR2260348A2 (en, 2012) |
| GB (1) | GB1437939A (en, 2012) |
| IE (1) | IE40752B1 (en, 2012) |
| IL (1) | IL46341A (en, 2012) |
| NL (1) | NL7501463A (en, 2012) |
| NO (1) | NO750394L (en, 2012) |
| PH (1) | PH11250A (en, 2012) |
| SE (1) | SE7501196L (en, 2012) |
| ZA (1) | ZA7548B (en, 2012) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4013647A (en) * | 1976-03-23 | 1977-03-22 | American Home Products Corporation | Morpholine containing tetrazole-5-carboxamide derivatives |
| US4254130A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| US4285958A (en) * | 1979-04-10 | 1981-08-25 | Richardson-Merrell Inc. | 1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof |
| US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| US4285957A (en) * | 1979-04-10 | 1981-08-25 | Richardson-Merrell Inc. | 1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof |
| US4810713A (en) * | 1985-12-20 | 1989-03-07 | A. H. Robins Company, Incorporated | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment |
| DE3917241A1 (de) * | 1989-05-26 | 1990-11-29 | Schaper & Bruemmer Gmbh | 4-(hydroxydiphenylmethyl)-1-piperidyl-phenylalkan-derivate |
| FI97540C (fi) * | 1989-11-06 | 1997-01-10 | Sanofi Sa | Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi |
| US5063235A (en) * | 1990-04-30 | 1991-11-05 | A. H. Robins Company, Inc. | 4-[(diaryl)hydromethyl]-1-piperidinealkanols and esters and carbamates thereof useful in the treatment of allergic disorders |
| US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
| PT1026147E (pt) * | 1993-06-24 | 2004-04-30 | Albany Molecular Res Inc | Compostos uteis como intermediarios na producao de derivados de piperidina |
| US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
| ATE230395T1 (de) | 1993-06-25 | 2003-01-15 | Merrell Pharma Inc | Neue zwischenprodukte für die herstellung von antihistaminschen 4- diphenylmethyl/diphenylmethoxypiperidin-derivat n |
| US6147216A (en) * | 1993-06-25 | 2000-11-14 | Merrell Pharmaceuticals Inc. | Intermediates useful for the preparation of antihistaminic piperidine derivatives |
| NZ302926A (en) * | 1995-02-28 | 1998-10-28 | Hoechst Marion Roussel Inc | Composition for use as antihistamines comprising piperidinoalkanol derivatives and inert ingredients |
| US6201124B1 (en) | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| US6153754A (en) | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| US6613907B2 (en) | 2000-11-08 | 2003-09-02 | Amr Technology, Inc. | Process for the production of piperidine derivatives with microorganisms |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3839431A (en) * | 1970-07-13 | 1974-10-01 | Squibb & Sons Inc | Cyclopropylmethylphenylacetic acids and derivatives |
| ZA728544B (en) | 1972-01-28 | 1974-02-27 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
| BE794596A (fr) * | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Piperidinoalcanone-oximes substituees et leur procede de preparation |
| US3806526A (en) * | 1972-01-28 | 1974-04-23 | Richardson Merrell Inc | 1-aroylalkyl-4-diphenylmethyl piperidines |
-
1974
- 1974-02-08 US US05/440,855 patent/US3941795A/en not_active Expired - Lifetime
- 1974-12-25 IL IL46341A patent/IL46341A/xx unknown
-
1975
- 1975-01-02 ZA ZA00750048A patent/ZA7548B/xx unknown
- 1975-01-03 IE IE19/75A patent/IE40752B1/xx unknown
- 1975-01-17 JP JP50007179A patent/JPS50108266A/ja active Pending
- 1975-01-27 GB GB339375A patent/GB1437939A/en not_active Expired
- 1975-01-28 DE DE19752503362 patent/DE2503362A1/de not_active Withdrawn
- 1975-01-31 CA CA219,191A patent/CA1082703A/en not_active Expired
- 1975-02-04 SE SE7501196A patent/SE7501196L/xx unknown
- 1975-02-04 CH CH129775A patent/CH609972A5/xx not_active IP Right Cessation
- 1975-02-06 FR FR7503733A patent/FR2260348A2/fr not_active Withdrawn
- 1975-02-06 DK DK41775*#A patent/DK41775A/da not_active Application Discontinuation
- 1975-02-07 NO NO750394A patent/NO750394L/no unknown
- 1975-02-07 NL NL7501463A patent/NL7501463A/xx not_active Application Discontinuation
- 1975-02-07 BE BE153164A patent/BE825302R/xx not_active IP Right Cessation
- 1975-02-10 PH PH16790A patent/PH11250A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL46341A (en) | 1978-09-29 |
| SE7501196L (en, 2012) | 1975-08-11 |
| AU7668874A (en) | 1976-06-24 |
| FR2260348A2 (en, 2012) | 1975-09-05 |
| US3941795A (en) | 1976-03-02 |
| ZA7548B (en) | 1976-01-28 |
| CH609972A5 (en, 2012) | 1979-03-30 |
| IE40752B1 (en) | 1979-08-15 |
| PH11250A (en) | 1977-10-28 |
| IE40752L (en) | 1975-08-08 |
| NL7501463A (nl) | 1975-08-12 |
| IL46341A0 (en) | 1975-03-13 |
| NO750394L (en, 2012) | 1975-09-01 |
| JPS50108266A (en, 2012) | 1975-08-26 |
| BE825302R (fr) | 1975-05-29 |
| DE2503362A1 (de) | 1975-08-21 |
| DK41775A (en, 2012) | 1975-10-06 |
| CA1082703A (en) | 1980-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1437939A (en) | Alpha-aryl-4-substituted piperidinoalkanol derivatives | |
| GB1437940A (en) | Substituted piperidine derivatives | |
| GB1422295A (en) | Indole derivatives | |
| GB1432576A (en) | Substituted phenylacetic acids | |
| GB1209946A (en) | Homopyrimidazole derivatives | |
| GEP19960467B (en) | Method of producing derivatives of quinoline or their pharmaceutically acceptable esters or acid-additive salts | |
| GB1159449A (en) | New Piperidinoalkanol Derivatives | |
| GB1527297A (en) | Pyrazine carboxamides | |
| GB1436771A (en) | Indole derivatives and process for preparing the same | |
| IE45256L (en) | Quinazolone derivatives | |
| EP0214659A3 (en) | Peptide derivatives, process for the production thereof and pharmaceutical compositions containing same | |
| GB1413892A (en) | 2-pyrimidinyl-thio-acetic acids and their derivatives | |
| IE34511L (en) | Piperazine ethers. | |
| GB1438265A (en, 2012) | ||
| IE880989L (en) | Method of improving sleep | |
| IE781071L (en) | Pyridobenzodiazepinones | |
| GB1417542A (en) | Theophylline 7acetate salts | |
| GB1457484A (en) | Acylamidocephalosporins | |
| GB1252329A (en, 2012) | ||
| GB1530299A (en) | Amino-substituted tetracyclic compounds | |
| SU586839A3 (ru) | Способ получени 1-/2-( -нафтилекси) -этил/-3-метилпиразолена-5 | |
| GB1347930A (en) | Imidazolines and a proces for the preparation thereof | |
| GB1334693A (en) | Acenaphthene derivatives | |
| GB1268469A (en) | Halomethylquinolylamino-benzamides | |
| GB1457005A (en) | 2-substituted-3-aminoquinoxalines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 746B | Proceeding under section 46(3) patents act 1977 | ||
| 746D | Case decided by the comptroller (sect. 46(3)/1977) |