GB1436549A - 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters - Google Patents
17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their estersInfo
- Publication number
- GB1436549A GB1436549A GB2811772A GB2811772A GB1436549A GB 1436549 A GB1436549 A GB 1436549A GB 2811772 A GB2811772 A GB 2811772A GB 2811772 A GB2811772 A GB 2811772A GB 1436549 A GB1436549 A GB 1436549A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- group
- oxy
- nitro
- steroids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 230000003444 anaesthetic effect Effects 0.000 abstract 2
- -1 cycloaliphatic Chemical group 0.000 abstract 2
- 230000032050 esterification Effects 0.000 abstract 2
- 238000005886 esterification reaction Methods 0.000 abstract 2
- CTSLXHKWHWQRSH-UHFFFAOYSA-N oxalyl chloride Chemical compound ClC(=O)C(Cl)=O CTSLXHKWHWQRSH-UHFFFAOYSA-N 0.000 abstract 2
- ZMDSGTVXUHPPLK-UHFFFAOYSA-N 1-morpholin-4-ylethanethiol Chemical compound CC(S)N1CCOCC1 ZMDSGTVXUHPPLK-UHFFFAOYSA-N 0.000 abstract 1
- DUHUCHOQIDJXAT-OLVMNOGESA-N 3-hydroxy-(3-α,5-α)-Pregnane-11,20-dione Chemical compound C([C@@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1=O DUHUCHOQIDJXAT-OLVMNOGESA-N 0.000 abstract 1
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002162 estranes Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- CRWJEUDFKNYSBX-UHFFFAOYSA-N sodium;hypobromite Chemical compound [Na+].Br[O-] CRWJEUDFKNYSBX-UHFFFAOYSA-N 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2811772A GB1436549A (en) | 1972-06-15 | 1972-06-15 | 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters |
| DE2330330A DE2330330A1 (de) | 1972-06-15 | 1973-04-21 | Steroidverbindungen |
| CA174,049A CA996928A (en) | 1972-06-15 | 1973-06-14 | Compounds of the androstane series having anaesthetic activity |
| IL42503A IL42503A0 (en) | 1972-06-15 | 1973-06-14 | Compounds of the androstane series having anaesthetic activity |
| LU67792A LU67792A1 (enrdf_load_stackoverflow) | 1972-06-15 | 1973-06-14 | |
| AU56938/73A AU474559B2 (en) | 1972-06-15 | 1973-06-14 | Compounds of the anorostane series having anaesthetic activity |
| ZA734036A ZA734036B (en) | 1972-06-15 | 1973-06-14 | Compounds of the androstane series having anaesthetic activity |
| NL7308268A NL7308268A (enrdf_load_stackoverflow) | 1972-06-15 | 1973-06-14 | |
| FR7321741A FR2189033B1 (enrdf_load_stackoverflow) | 1972-06-15 | 1973-06-14 | |
| BE132253A BE800898A (fr) | 1972-06-15 | 1973-06-14 | Nouveaux composes steroides a activite anesthesique et leur preparation |
| US05/505,763 US3989686A (en) | 1972-06-15 | 1974-09-13 | Anaesthetic steroids of the androstane series and process for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2811772A GB1436549A (en) | 1972-06-15 | 1972-06-15 | 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1436549A true GB1436549A (en) | 1976-05-19 |
Family
ID=10270541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2811772A Expired GB1436549A (en) | 1972-06-15 | 1972-06-15 | 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters |
Country Status (10)
| Country | Link |
|---|---|
| AU (1) | AU474559B2 (enrdf_load_stackoverflow) |
| BE (1) | BE800898A (enrdf_load_stackoverflow) |
| CA (1) | CA996928A (enrdf_load_stackoverflow) |
| DE (1) | DE2330330A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2189033B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1436549A (enrdf_load_stackoverflow) |
| IL (1) | IL42503A0 (enrdf_load_stackoverflow) |
| LU (1) | LU67792A1 (enrdf_load_stackoverflow) |
| NL (1) | NL7308268A (enrdf_load_stackoverflow) |
| ZA (1) | ZA734036B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1170717B (it) * | 1980-02-15 | 1987-06-03 | Glaxo Group Ltd | Carbotioati androstanici procedimento per prepararli e composizioni farmaceutiche che li contengono |
-
1972
- 1972-06-15 GB GB2811772A patent/GB1436549A/en not_active Expired
-
1973
- 1973-04-21 DE DE2330330A patent/DE2330330A1/de active Pending
- 1973-06-14 IL IL42503A patent/IL42503A0/xx unknown
- 1973-06-14 LU LU67792A patent/LU67792A1/xx unknown
- 1973-06-14 BE BE132253A patent/BE800898A/xx unknown
- 1973-06-14 NL NL7308268A patent/NL7308268A/xx unknown
- 1973-06-14 ZA ZA734036A patent/ZA734036B/xx unknown
- 1973-06-14 CA CA174,049A patent/CA996928A/en not_active Expired
- 1973-06-14 FR FR7321741A patent/FR2189033B1/fr not_active Expired
- 1973-06-14 AU AU56938/73A patent/AU474559B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL42503A0 (en) | 1973-08-29 |
| FR2189033A1 (enrdf_load_stackoverflow) | 1974-01-25 |
| ZA734036B (en) | 1974-05-29 |
| NL7308268A (enrdf_load_stackoverflow) | 1973-12-18 |
| AU474559B2 (en) | 1976-07-29 |
| BE800898A (fr) | 1973-12-14 |
| DE2330330A1 (de) | 1974-01-17 |
| AU5693873A (en) | 1974-12-19 |
| FR2189033B1 (enrdf_load_stackoverflow) | 1977-01-28 |
| LU67792A1 (enrdf_load_stackoverflow) | 1973-08-16 |
| CA996928A (en) | 1976-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |