GB1435295A - Bone seeking technetium-99m complex - Google Patents

Bone seeking technetium-99m complex

Info

Publication number
GB1435295A
GB1435295A GB4606475A GB4606475A GB1435295A GB 1435295 A GB1435295 A GB 1435295A GB 4606475 A GB4606475 A GB 4606475A GB 4606475 A GB4606475 A GB 4606475A GB 1435295 A GB1435295 A GB 1435295A
Authority
GB
United Kingdom
Prior art keywords
complex
technetium
salt
bone seeking
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4606475A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Priority to GB4606475A priority Critical patent/GB1435295A/en
Publication of GB1435295A publication Critical patent/GB1435295A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Abstract

1435295 Radio-active substances RESEARCH CORP 19 Nov 1973 46064/75 Divided out of 1429549 Heading G6R The invention comprises a complex of technetium 99 m and tin-1-amino-ethane-1,1- diphosphonate. The complex may be made by mixing in aqueous solution a stannous salt, e.g. the chloride, sulphate, or acetate, 1-aminoethane-1,1-diphosphonic acid or a salt thereof, and a pertechnetate salt containing Tc99m. A solution of the complex is suitable for use by intravenous administration in skeletal imaging.
GB4606475A 1973-11-19 1973-11-19 Bone seeking technetium-99m complex Expired GB1435295A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4606475A GB1435295A (en) 1973-11-19 1973-11-19 Bone seeking technetium-99m complex

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4606475A GB1435295A (en) 1973-11-19 1973-11-19 Bone seeking technetium-99m complex

Publications (1)

Publication Number Publication Date
GB1435295A true GB1435295A (en) 1976-05-12

Family

ID=10439706

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4606475A Expired GB1435295A (en) 1973-11-19 1973-11-19 Bone seeking technetium-99m complex

Country Status (1)

Country Link
GB (1) GB1435295A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092723A2 (en) * 1999-10-12 2001-04-18 NIHON MEDI-PHYSICS Co., Ltd. Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide
FR2848850A1 (en) * 2002-12-20 2004-06-25 Guerbet Sa Composition comprising acidic magnetic particles complexed with gem-bis-phosphonate compound, optionally coupled with biological vector, useful e.g. as NMR contrast agents or in hyperthermia therapy

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092723A2 (en) * 1999-10-12 2001-04-18 NIHON MEDI-PHYSICS Co., Ltd. Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide
EP1092723A3 (en) * 1999-10-12 2001-09-26 NIHON MEDI-PHYSICS Co., Ltd. Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide
US6607710B1 (en) 1999-10-12 2003-08-19 Nihon Medi-Physics Co., Ltd. Bisphosphonic acid derivative and compound thereof labeled with radioactive nuclide
FR2848850A1 (en) * 2002-12-20 2004-06-25 Guerbet Sa Composition comprising acidic magnetic particles complexed with gem-bis-phosphonate compound, optionally coupled with biological vector, useful e.g. as NMR contrast agents or in hyperthermia therapy
WO2004058275A2 (en) * 2002-12-20 2004-07-15 Guerbet Compositions of magnetic particles covered with gem-bisphosphonate derivatives
WO2004058275A3 (en) * 2002-12-20 2004-12-09 Guerbet Sa Compositions of magnetic particles covered with gem-bisphosphonate derivatives
US7780953B2 (en) 2002-12-20 2010-08-24 Guerbet Compositions magnetic particles covered with gem-bisphosphonate derivatives

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee