GB1434854A - Thiophene derivatives - Google Patents
Thiophene derivativesInfo
- Publication number
- GB1434854A GB1434854A GB944374A GB944374A GB1434854A GB 1434854 A GB1434854 A GB 1434854A GB 944374 A GB944374 A GB 944374A GB 944374 A GB944374 A GB 944374A GB 1434854 A GB1434854 A GB 1434854A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- alkyl
- absent
- groups
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003577 thiophenes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 3
- FMCAFXHLMUOIGG-JTJHWIPRSA-N (2s)-2-[[(2r)-2-[[(2s)-2-[[(2r)-2-formamido-3-sulfanylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxy-2,5-dimethylphenyl)propanoyl]amino]-4-methylsulfanylbutanoic acid Chemical compound O=CN[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(=O)N[C@@H](CCSC)C(O)=O)CC1=CC(C)=C(O)C=C1C FMCAFXHLMUOIGG-JTJHWIPRSA-N 0.000 abstract 2
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- FMCAFXHLMUOIGG-IWFBPKFRSA-N (2s)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-formamido-3-sulfanylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxy-2,5-dimethylphenyl)propanoyl]amino]-4-methylsulfanylbutanoic acid Chemical compound O=CN[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(O)=O)CC1=CC(C)=C(O)C=C1C FMCAFXHLMUOIGG-IWFBPKFRSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- FCSKOFQQCWLGMV-UHFFFAOYSA-N 5-{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methylisoxazole Chemical compound O1N=C(C)C=C1CCCCCOC1=CC=C(C=2OCCN=2)C=C1Cl FCSKOFQQCWLGMV-UHFFFAOYSA-N 0.000 abstract 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 125000005279 aryl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- AGJSNMGHAVDLRQ-IWFBPKFRSA-N methyl (2s)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-amino-3-sulfanylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxy-2,3-dimethylphenyl)propanoyl]amino]-4-methylsulfanylbutanoate Chemical compound SC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)OC)CC1=CC=C(O)C(C)=C1C AGJSNMGHAVDLRQ-IWFBPKFRSA-N 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732310215 DE2310215A1 (de) | 1973-03-01 | 1973-03-01 | Neue thiophenderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1434854A true GB1434854A (en) | 1976-05-05 |
Family
ID=5873510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB944374A Expired GB1434854A (en) | 1973-03-01 | 1974-03-01 | Thiophene derivatives |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5040582A (enrdf_load_stackoverflow) |
| AT (1) | AT342595B (enrdf_load_stackoverflow) |
| BE (1) | BE811560A (enrdf_load_stackoverflow) |
| CH (2) | CH603624A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2310215A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2219780B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1434854A (enrdf_load_stackoverflow) |
| NL (1) | NL7402790A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994024116A1 (en) * | 1993-04-09 | 1994-10-27 | Syntex Pharmaceuticals Limited | Heterocyclic derivatives in the treatment of ischaemia and related diseases |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5195086A (ja) * | 1975-02-13 | 1976-08-20 | Homopiperajinjudotaino seizoho | |
| JPS57127493U (enrdf_load_stackoverflow) * | 1981-02-03 | 1982-08-09 | ||
| JPH0760722B2 (ja) * | 1988-07-29 | 1995-06-28 | 日本電気株式会社 | 集積回路ソケット |
| JP4139959B2 (ja) * | 2002-10-21 | 2008-08-27 | 株式会社安川電機 | 多軸用サーボアンプ装置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1935558A1 (de) * | 1969-07-12 | 1971-01-28 | Hoechst Ag | Tiophenaether und Verfahren zu deren Darstellung |
-
1973
- 1973-03-01 DE DE19732310215 patent/DE2310215A1/de active Pending
-
1974
- 1974-02-26 BE BE141373A patent/BE811560A/xx unknown
- 1974-02-28 AT AT164474A patent/AT342595B/de not_active IP Right Cessation
- 1974-02-28 JP JP2290274A patent/JPS5040582A/ja active Pending
- 1974-02-28 FR FR7406784A patent/FR2219780B1/fr not_active Expired
- 1974-02-28 CH CH509877A patent/CH603624A5/xx not_active IP Right Cessation
- 1974-02-28 CH CH284674A patent/CH602714A5/xx not_active IP Right Cessation
- 1974-03-01 NL NL7402790A patent/NL7402790A/xx not_active Application Discontinuation
- 1974-03-01 GB GB944374A patent/GB1434854A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994024116A1 (en) * | 1993-04-09 | 1994-10-27 | Syntex Pharmaceuticals Limited | Heterocyclic derivatives in the treatment of ischaemia and related diseases |
| US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| CH602714A5 (enrdf_load_stackoverflow) | 1978-07-31 |
| DE2310215A1 (de) | 1974-09-12 |
| FR2219780B1 (enrdf_load_stackoverflow) | 1978-01-06 |
| FR2219780A1 (enrdf_load_stackoverflow) | 1974-09-27 |
| JPS5040582A (enrdf_load_stackoverflow) | 1975-04-14 |
| CH603624A5 (enrdf_load_stackoverflow) | 1978-08-31 |
| NL7402790A (enrdf_load_stackoverflow) | 1974-09-03 |
| BE811560A (fr) | 1974-08-26 |
| AT342595B (de) | 1978-04-10 |
| ATA164474A (de) | 1977-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1323283A (en) | Benzothiazine 1,1, dioxide derivatives | |
| NO982921D0 (no) | Nye kromenforbindelser, en fremgangsmÕte for deres fremstilling og farmas°ytiske sammensetninger som inneholder disse | |
| GB1434854A (en) | Thiophene derivatives | |
| GB1262965A (en) | Butyrophenones | |
| GB1275525A (en) | Ureidophenyguanidines, process for their preparation, and their fungicidal use | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1249261A (en) | Mannich-bases | |
| EP0712398A1 (en) | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| GB1450211A (en) | 5-methylthiopyrimidines their preparation and use | |
| DE3267188D1 (en) | Hydroxybenzylamino-aryl compounds, process for preparing and pharmaceutical compositions containing the same | |
| GB1427160A (en) | Oxazolidines and oxazolidinones and process for their production | |
| GB1474133A (en) | Benzindole derivatives | |
| GB1185334A (en) | Thienobenzothiazepines | |
| FR2100682B1 (enrdf_load_stackoverflow) | ||
| ES2174077T3 (es) | Derivados de hidroxilamina antiisquemicos y composiciones farmaceuticas. | |
| GB1337506A (en) | Oxobenzofuran carboxamide anti-inflammatory agents | |
| ES442321A1 (es) | Procedimiento para preparar derivados de benceno. | |
| GB1384523A (en) | Oxime derivatives and their preparation | |
| GB1227967A (enrdf_load_stackoverflow) | ||
| ES2024332A6 (es) | Procedimiento para la obtencion de nuevas sulfonamidas. | |
| GB1361368A (en) | Pyrido 4,3-c pyridazine compounds | |
| ES378917A1 (es) | Metodo para preparar una amida formacodinamicamente activa. | |
| GB1339010A (en) | Tetrazolyl-anthraquinone derivatives | |
| GB1470675A (en) | 1,2,3,4-tetrahydroisoquinoline derivatives and the preparation thereof | |
| GB1114424A (en) | 4-arylpiperidines,their acid addition salts,and processes for the preparation thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |