GB1432678A - Process for the preparation of aminoadamantane derivatives - Google Patents
Process for the preparation of aminoadamantane derivativesInfo
- Publication number
- GB1432678A GB1432678A GB1943573A GB1943573A GB1432678A GB 1432678 A GB1432678 A GB 1432678A GB 1943573 A GB1943573 A GB 1943573A GB 1943573 A GB1943573 A GB 1943573A GB 1432678 A GB1432678 A GB 1432678A
- Authority
- GB
- United Kingdom
- Prior art keywords
- adamantyl
- treating
- aminoadamantane
- haloacetamide
- acetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical class C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 title abstract 4
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- PQHZQFSHDCCCBY-UHFFFAOYSA-N N-(1-adamantyl)-2-[2-(1,3-dioxoisoindol-2-yl)ethoxy]acetamide Chemical compound C12(CC3CC(CC(C1)C3)C2)NC(COCCN2C(C=3C(C2=O)=CC=CC3)=O)=O PQHZQFSHDCCCBY-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical compound C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732316839 DE2316839C2 (de) | 1973-04-04 | 1973-04-04 | Verfahren zur Herstellung von Aminoadamantan-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1432678A true GB1432678A (en) | 1976-04-22 |
Family
ID=5876993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1943573A Expired GB1432678A (en) | 1973-04-04 | 1973-04-24 | Process for the preparation of aminoadamantane derivatives |
Country Status (12)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6221991U (enrdf_load_stackoverflow) * | 1985-07-25 | 1987-02-09 |
-
1973
- 1973-04-04 DE DE19732316839 patent/DE2316839C2/de not_active Expired
- 1973-04-11 AT AT319473A patent/AT325592B/de not_active IP Right Cessation
- 1973-04-12 SE SE7305183A patent/SE385874B/xx unknown
- 1973-04-19 CH CH566973A patent/CH553748A/xx not_active IP Right Cessation
- 1973-04-24 BE BE130325A patent/BE798609R/xx not_active IP Right Cessation
- 1973-04-24 GB GB1943573A patent/GB1432678A/en not_active Expired
- 1973-05-02 NL NL7306130A patent/NL7306130A/xx unknown
- 1973-05-09 JP JP5156473A patent/JPS5720295B2/ja not_active Expired
- 1973-05-12 ES ES414716A patent/ES414716A2/es not_active Expired
- 1973-06-04 CA CA173,060A patent/CA962674A/en not_active Expired
- 1973-06-22 PL PL16352173A patent/PL83827B1/pl unknown
- 1973-07-04 FR FR7324580A patent/FR2224446B2/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA962674A (en) | 1975-02-11 |
| BE798609R (fr) | 1973-08-16 |
| JPS49127957A (enrdf_load_stackoverflow) | 1974-12-07 |
| ATA319473A (de) | 1975-01-15 |
| PL83827B1 (enrdf_load_stackoverflow) | 1976-02-28 |
| DE2316839C2 (de) | 1983-04-28 |
| FR2224446B2 (enrdf_load_stackoverflow) | 1976-06-18 |
| DE2316839A1 (de) | 1974-10-17 |
| AT325592B (de) | 1975-10-27 |
| NL7306130A (enrdf_load_stackoverflow) | 1974-10-08 |
| ES414716A2 (es) | 1976-03-01 |
| SE385874B (sv) | 1976-07-26 |
| FR2224446A2 (enrdf_load_stackoverflow) | 1974-10-31 |
| JPS5720295B2 (enrdf_load_stackoverflow) | 1982-04-27 |
| CH553748A (de) | 1974-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |