GB1428041A - Digitoxin esters - Google Patents
Digitoxin estersInfo
- Publication number
- GB1428041A GB1428041A GB2585273A GB2585273A GB1428041A GB 1428041 A GB1428041 A GB 1428041A GB 2585273 A GB2585273 A GB 2585273A GB 2585273 A GB2585273 A GB 2585273A GB 1428041 A GB1428041 A GB 1428041A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- digitoxin
- esters
- cycloalkyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WDJUZGPOPHTGOT-XUDUSOBPSA-N digitoxin Chemical class C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)CC5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O WDJUZGPOPHTGOT-XUDUSOBPSA-N 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- WDJUZGPOPHTGOT-OAXVISGBSA-N Digitoxin Natural products O([C@H]1[C@@H](C)O[C@@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@@](C)([C@H](C6=CC(=O)OC6)CC5)CC4)CC3)CC2)C[C@H]1O)[C@H]1O[C@@H](C)[C@H](O[C@H]2O[C@@H](C)[C@@H](O)[C@@H](O)C2)[C@@H](O)C1 WDJUZGPOPHTGOT-OAXVISGBSA-N 0.000 abstract 2
- 229960000648 digitoxin Drugs 0.000 abstract 2
- -1 (trifluoroacetamido)ethyl Chemical group 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722226398 DE2226398A1 (de) | 1972-05-31 | 1972-05-31 | Neue herzglykoside und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1428041A true GB1428041A (en) | 1976-03-17 |
Family
ID=5846376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2585273A Expired GB1428041A (en) | 1972-05-31 | 1973-05-30 | Digitoxin esters |
Country Status (11)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023092188A1 (en) * | 2021-11-26 | 2023-06-01 | DemAgtech Pty Ltd | "compounds and methods" |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1325014B1 (en) * | 2000-09-22 | 2012-05-23 | JPI Commercial, LLC | Gamma-hydroxybutyrate compositions containing carbohydrate carriers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1259954A (fr) * | 1953-06-05 | 1961-05-05 | Sandoz Ag | Procédé de préparation de l'acétyl digitoxine-alpha |
| FR1479268A (fr) * | 1964-12-19 | 1967-05-05 | Kutnowskie Zakl Farma | Procédé de production de l'alpha-acétyldigitoxyine |
| RO60624A (enrdf_load_stackoverflow) * | 1970-03-05 | 1976-07-15 |
-
1972
- 1972-05-31 DE DE19722226398 patent/DE2226398A1/de active Pending
-
1973
- 1973-05-21 AT AT439873A patent/AT328093B/de not_active IP Right Cessation
- 1973-05-28 CH CH765473A patent/CH577528A5/xx not_active IP Right Cessation
- 1973-05-30 FR FR7319898A patent/FR2186264B1/fr not_active Expired
- 1973-05-30 JP JP6076073A patent/JPS4961155A/ja active Pending
- 1973-05-30 FI FI174773A patent/FI52348C/fi active
- 1973-05-30 ES ES415421A patent/ES415421A1/es not_active Expired
- 1973-05-30 BE BE131787A patent/BE800343A/xx unknown
- 1973-05-30 DK DK300273A patent/DK132832C/da active
- 1973-05-30 NL NL7307540A patent/NL7307540A/xx unknown
- 1973-05-30 GB GB2585273A patent/GB1428041A/en not_active Expired
-
1974
- 1974-02-22 ES ES0423500A patent/ES423500A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023092188A1 (en) * | 2021-11-26 | 2023-06-01 | DemAgtech Pty Ltd | "compounds and methods" |
Also Published As
| Publication number | Publication date |
|---|---|
| AU5631673A (en) | 1974-12-05 |
| JPS4961155A (enrdf_load_stackoverflow) | 1974-06-13 |
| FI52348C (fi) | 1977-08-10 |
| ES415421A1 (es) | 1976-06-01 |
| ES423500A1 (es) | 1976-11-16 |
| AT328093B (de) | 1976-03-10 |
| DK132832C (da) | 1976-07-19 |
| DE2226398A1 (de) | 1973-12-13 |
| ATA439873A (de) | 1975-05-15 |
| FR2186264B1 (enrdf_load_stackoverflow) | 1976-07-02 |
| FI52348B (enrdf_load_stackoverflow) | 1977-05-02 |
| BE800343A (fr) | 1973-11-30 |
| FR2186264A1 (enrdf_load_stackoverflow) | 1974-01-11 |
| NL7307540A (enrdf_load_stackoverflow) | 1973-12-04 |
| CH577528A5 (enrdf_load_stackoverflow) | 1976-07-15 |
| DK132832B (da) | 1976-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |