GB1428041A - Digitoxin esters - Google Patents

Digitoxin esters

Info

Publication number
GB1428041A
GB1428041A GB2585273A GB2585273A GB1428041A GB 1428041 A GB1428041 A GB 1428041A GB 2585273 A GB2585273 A GB 2585273A GB 2585273 A GB2585273 A GB 2585273A GB 1428041 A GB1428041 A GB 1428041A
Authority
GB
United Kingdom
Prior art keywords
alkyl
digitoxin
esters
cycloalkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2585273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1428041A publication Critical patent/GB1428041A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1428041 Digitoxin esters BOEHRINGER INGELHEIM GmbH 30 May 1973 [31 May 1972] 25852/73 Heading C2U The invention comprises digitoxin 3<SP>111</SP>-esters with R<SP>2</SP>CO 2 H where R<SP>2</SP> is C 2 -C 15 alkyl, halo- C 1 -C 4 alkyl, cyano-C 1 -C 4 alkyl, ethoxycarbonyl-C 1 -C 4 alkyl, phenyl-C 1 -C 4 alkyl, phenoxy-C 1 -C 4 alkyl (said phenyl and phenoxy moieties being optionally substituted), C 3 -C 6 cycloalkyl, (C 3 -C 6 cycloalkyl)methyl or (trifluoroacetamido)ethyl; and their preparation from digitoxin by esterification, either direct or via 3<SP>111</SP>,4<SP>111</SP>-(alkyl orthoesters). Cardiotonic compositions for oral, rectal and parenteral administration comprise a carrier and a compound of the invention.
GB2585273A 1972-05-31 1973-05-30 Digitoxin esters Expired GB1428041A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722226398 DE2226398A1 (en) 1972-05-31 1972-05-31 NEW HEART GLYCOSIDES AND METHODS FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
GB1428041A true GB1428041A (en) 1976-03-17

Family

ID=5846376

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2585273A Expired GB1428041A (en) 1972-05-31 1973-05-30 Digitoxin esters

Country Status (11)

Country Link
JP (1) JPS4961155A (en)
AT (1) AT328093B (en)
BE (1) BE800343A (en)
CH (1) CH577528A5 (en)
DE (1) DE2226398A1 (en)
DK (1) DK132832C (en)
ES (2) ES415421A1 (en)
FI (1) FI52348C (en)
FR (1) FR2186264B1 (en)
GB (1) GB1428041A (en)
NL (1) NL7307540A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023092188A1 (en) * 2021-11-26 2023-06-01 DemAgtech Pty Ltd "compounds and methods"

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001291173A1 (en) * 2000-09-22 2002-04-02 Orphan Medical, Inc. Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1259954A (en) * 1953-06-05 1961-05-05 Sandoz Ag Process for preparing acetyl digitoxin-alpha
FR1479268A (en) * 1964-12-19 1967-05-05 Kutnowskie Zakl Farma Process for the production of alpha-acetyldigitoxyin
RO60624A (en) * 1970-03-05 1976-07-15

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023092188A1 (en) * 2021-11-26 2023-06-01 DemAgtech Pty Ltd "compounds and methods"

Also Published As

Publication number Publication date
ES415421A1 (en) 1976-06-01
ATA439873A (en) 1975-05-15
FR2186264A1 (en) 1974-01-11
ES423500A1 (en) 1976-11-16
AT328093B (en) 1976-03-10
FR2186264B1 (en) 1976-07-02
BE800343A (en) 1973-11-30
DK132832B (en) 1976-02-16
CH577528A5 (en) 1976-07-15
JPS4961155A (en) 1974-06-13
NL7307540A (en) 1973-12-04
FI52348B (en) 1977-05-02
DE2226398A1 (en) 1973-12-13
AU5631673A (en) 1974-12-05
FI52348C (en) 1977-08-10
DK132832C (en) 1976-07-19

Similar Documents

Publication Publication Date Title
GB1453425A (en) 2-oxo-tetrahydropyran derivatives and fermentative process for producing the same
GB1324646A (en) Nitrofurylpyrimidine derivatives
GB1515284A (en) Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series
GB1205957A (en) Pharmaceutical compositions comprising 1-pnenoxy-2-aminopropanes
GB1507957A (en) Nitrofuryl-pyrazole derivatives methods for producing them and medicaments comprising them
GB1491825A (en) Hindered hydroxyphenylalkanoates of substituted isopropanols and stabilized compositions
GB1428041A (en) Digitoxin esters
GB1506823A (en) Prostaglandins
ES406143A1 (en) Tricycloalkyl tin 1,2,4-triazole compounds
GB1274809A (en) Evomonoside derivatives
ES8304586A1 (en) At position 17 esterified and at position 21 thio-esterified steroids, process for their preparation and their utilisation as pharmaceutical preparations.
GB1511173A (en) Proscillaridin derivative
GB1478988A (en) Digitoxin orthoformates
GB1474749A (en) Pharmaceutical preparations based on cyproterone
GB1155512A (en) Novel 4-Oxa-Steroids
GB1378605A (en) Derivatives of dihydrodigoxin
GB1420533A (en) Pyridine derivatives having juvenile hormone activity
GB1468079A (en) Ethanolamine derivatives
GB1355663A (en) 19-nortestosterone 17- -p-substituted phenoxy-acetates
GB1272340A (en) Derivatives of neriifolin
ES356821A1 (en) Novel 2,2-dimethyl steroids
GB1419216A (en) Oleandrin derivative
GB1457396A (en) Gona-4,9,11-triene derivative process for its preparation and compositions incorporating it
GB1363033A (en) Derivatives of 22-fluoro-digoxins
GB1375817A (en)

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee