GB1426186A - Process for the resolution of d,1 2- 6-methoxy-2-naphthyl- propionic acid - Google Patents
Process for the resolution of d,1 2- 6-methoxy-2-naphthyl- propionic acidInfo
- Publication number
- GB1426186A GB1426186A GB3026873A GB3026873A GB1426186A GB 1426186 A GB1426186 A GB 1426186A GB 3026873 A GB3026873 A GB 3026873A GB 3026873 A GB3026873 A GB 3026873A GB 1426186 A GB1426186 A GB 1426186A
- Authority
- GB
- United Kingdom
- Prior art keywords
- naphthyl
- methoxy
- propionic acid
- salt
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 9
- 150000003839 salts Chemical class 0.000 abstract 9
- 239000008346 aqueous phase Substances 0.000 abstract 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- JVVXZOOGOGPDRZ-SLFFLAALSA-N [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine Chemical compound NC[C@]1(C)CCC[C@]2(C)C3=CC=C(C(C)C)C=C3CC[C@H]21 JVVXZOOGOGPDRZ-SLFFLAALSA-N 0.000 abstract 3
- 239000012074 organic phase Substances 0.000 abstract 3
- 239000012071 phase Substances 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 1
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000012452 mother liquor Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000003495 polar organic solvent Substances 0.000 abstract 1
- 238000005185 salting out Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27932972A | 1972-08-10 | 1972-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1426186A true GB1426186A (en) | 1976-02-25 |
Family
ID=23068502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3026873A Expired GB1426186A (en) | 1972-08-10 | 1973-06-26 | Process for the resolution of d,1 2- 6-methoxy-2-naphthyl- propionic acid |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5339421B2 (enExample) |
| AU (1) | AU474834B2 (enExample) |
| BE (1) | BE803394A (enExample) |
| CA (1) | CA1000731A (enExample) |
| CH (1) | CH581602A5 (enExample) |
| ES (1) | ES417692A1 (enExample) |
| FR (1) | FR2195438B1 (enExample) |
| GB (1) | GB1426186A (enExample) |
| IL (1) | IL42485A (enExample) |
| NL (1) | NL7310838A (enExample) |
| SE (1) | SE406320B (enExample) |
-
1973
- 1973-06-12 IL IL42485A patent/IL42485A/en unknown
- 1973-06-13 CA CA173,978A patent/CA1000731A/en not_active Expired
- 1973-06-26 GB GB3026873A patent/GB1426186A/en not_active Expired
- 1973-06-29 AU AU57511/73A patent/AU474834B2/en not_active Expired
- 1973-07-10 JP JP7782073A patent/JPS5339421B2/ja not_active Expired
- 1973-07-30 CH CH1108273A patent/CH581602A5/xx not_active IP Right Cessation
- 1973-08-06 FR FR7328746A patent/FR2195438B1/fr not_active Expired
- 1973-08-06 NL NL7310838A patent/NL7310838A/xx not_active Application Discontinuation
- 1973-08-08 ES ES417692A patent/ES417692A1/es not_active Expired
- 1973-08-09 SE SE7310932A patent/SE406320B/xx unknown
- 1973-08-09 BE BE134386A patent/BE803394A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE803394A (fr) | 1974-02-11 |
| AU474834B2 (en) | 1976-08-05 |
| IL42485A (en) | 1977-05-31 |
| JPS5339421B2 (enExample) | 1978-10-21 |
| FR2195438B1 (enExample) | 1976-10-22 |
| DE2339765B2 (de) | 1976-04-29 |
| NL7310838A (enExample) | 1974-02-12 |
| DE2339765A1 (de) | 1974-02-28 |
| CA1000731A (en) | 1976-11-30 |
| AU5751173A (en) | 1975-01-09 |
| ES417692A1 (es) | 1976-05-16 |
| CH581602A5 (enExample) | 1976-11-15 |
| FR2195438A1 (enExample) | 1974-03-08 |
| JPS4945047A (enExample) | 1974-04-27 |
| IL42485A0 (en) | 1973-08-29 |
| SE406320B (sv) | 1979-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |