GB1420355A - Carboxy-containing diphenyl ketones and processes for preparing them - Google Patents
Carboxy-containing diphenyl ketones and processes for preparing themInfo
- Publication number
- GB1420355A GB1420355A GB933773A GB933773A GB1420355A GB 1420355 A GB1420355 A GB 1420355A GB 933773 A GB933773 A GB 933773A GB 933773 A GB933773 A GB 933773A GB 1420355 A GB1420355 A GB 1420355A
- Authority
- GB
- United Kingdom
- Prior art keywords
- appropriately substituted
- alkyl
- group
- anhydride
- feb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title abstract 3
- 150000008366 benzophenones Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 4
- AKHSBAVQPIRVAG-UHFFFAOYSA-N 4h-isochromene-1,3-dione Chemical class C1=CC=C2C(=O)OC(=O)CC2=C1 AKHSBAVQPIRVAG-UHFFFAOYSA-N 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001555 benzenes Chemical class 0.000 abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical class OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- JHIWVOJDXOSYLW-UHFFFAOYSA-N butyl 2,2-difluorocyclopropane-1-carboxylate Chemical class CCCCOC(=O)C1CC1(F)F JHIWVOJDXOSYLW-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- ZHQLTKAVLJKSKR-UHFFFAOYSA-N homophthalic acid Chemical class OC(=O)CC1=CC=CC=C1C(O)=O ZHQLTKAVLJKSKR-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- IQZZFVDIZRWADY-UHFFFAOYSA-N isocoumarin Chemical compound C1=CC=C2C(=O)OC=CC2=C1 IQZZFVDIZRWADY-UHFFFAOYSA-N 0.000 abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 2
- YRTPZXMEBGTPLM-UVTDQMKNSA-N (3z)-3-benzylidene-2-benzofuran-1-one Chemical compound C12=CC=CC=C2C(=O)O\C1=C/C1=CC=CC=C1 YRTPZXMEBGTPLM-UVTDQMKNSA-N 0.000 abstract 1
- LGRFSURHDFAFJT-UHFFFAOYSA-N Phthalic anhydride Natural products C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005157 alkyl carboxy group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229940073608 benzyl chloride Drugs 0.000 abstract 1
- 150000005524 benzylchlorides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229960003424 phenylacetic acid Drugs 0.000 abstract 1
- 239000003279 phenylacetic acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/373—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7206402A FR2172868A1 (en) | 1972-02-24 | 1972-02-24 | Carboxy substd benzophenone derivs - as analgesics and antiinflammatory agents |
| FR7303898A FR2257281A2 (en) | 1973-02-02 | 1973-02-02 | Carboxy substd benzophenone derivs - as analgesics and antiinflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1420355A true GB1420355A (en) | 1976-01-07 |
Family
ID=26216936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB933773A Expired GB1420355A (en) | 1972-02-24 | 1973-02-26 | Carboxy-containing diphenyl ketones and processes for preparing them |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE795722A (enExample) |
| CH (1) | CH563954A5 (enExample) |
| DE (1) | DE2308553A1 (enExample) |
| ES (1) | ES411993A1 (enExample) |
| GB (1) | GB1420355A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006121390A3 (en) * | 2005-05-09 | 2007-01-11 | Astrazeneca Ab | Benzoic acid derivatives that are modulators or agonists of glyr |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3326164A1 (de) * | 1983-07-20 | 1985-01-31 | Klinge Pharma GmbH, 8000 München | Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
0
- BE BE795722D patent/BE795722A/xx unknown
-
1973
- 1973-02-21 DE DE19732308553 patent/DE2308553A1/de active Pending
- 1973-02-23 CH CH268873A patent/CH563954A5/xx not_active IP Right Cessation
- 1973-02-23 ES ES411993A patent/ES411993A1/es not_active Expired
- 1973-02-26 GB GB933773A patent/GB1420355A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006121390A3 (en) * | 2005-05-09 | 2007-01-11 | Astrazeneca Ab | Benzoic acid derivatives that are modulators or agonists of glyr |
Also Published As
| Publication number | Publication date |
|---|---|
| CH563954A5 (enExample) | 1975-07-15 |
| ES411993A1 (es) | 1976-05-01 |
| BE795722A (fr) | 1973-06-18 |
| DE2308553A1 (de) | 1973-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1432576A (en) | Substituted phenylacetic acids | |
| GB1467927A (en) | Derivatives of tyrosine having a pharmaceutical activity on smooth muscles | |
| GB1322988A (en) | Thiaheterocyclyl-acetic acid derivatives | |
| GB1367677A (en) | Optically active basically substituted phenylacetonitriles | |
| GB1420411A (en) | Pyridine compounds and process for their manufacture | |
| SE7608037L (sv) | 2-substituerade oxazolopyridiner | |
| GB1196229A (en) | Improvements in or relating to a New Glyoxylic Acid Salt, process for its preparation and Therapeutical Composition containing same | |
| GB1420355A (en) | Carboxy-containing diphenyl ketones and processes for preparing them | |
| GB1471910A (en) | Lysine salt | |
| GB1265279A (enExample) | ||
| GB1273705A (en) | A method for producing 3,5-diaryl-4-pyrazole acetic acids | |
| GB1359560A (en) | Preparation of pyrrylsalicylic acid | |
| ES427115A1 (es) | Procedimiento de preparacion de nuevos derivados del acido acetico. | |
| GB1490290A (en) | Preparation of penicillanic acid derivatives | |
| GB1291571A (en) | Aza chromone-2-carboxylic acids | |
| GB1371939A (en) | Pyridine carboxamides | |
| GB1283804A (en) | A process for the manufacture of amino acids and derivatives thereof | |
| GB1126860A (en) | Novel 4-substituted-7- and 8-chloroquinolines and a process for the preparation thereof | |
| GB1364620A (en) | Derivatives of 4.7-dihydroxycoumarin and a method of producing same | |
| GB1310779A (en) | N-pyridylalkyl-beta-alkoxy-beta-trifluoromethylphenalkylamines | |
| ES406329A1 (es) | Procedimiento de preparacion de nuevos derivados del acido fenilacetico. | |
| GB1284423A (en) | Cyclohexa-1,4-diene-1-acetic acids | |
| GB1180250A (en) | Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same | |
| GB1341612A (en) | Theophylline isobutyrate salts and process for the preparation thereof | |
| GB1166758A (en) | Phenoxyacetic Acids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |