GB1419969A - Immunostimulant agent compositions thereof and methods for their preparation - Google Patents
Immunostimulant agent compositions thereof and methods for their preparationInfo
- Publication number
- GB1419969A GB1419969A GB5916472A GB5916472A GB1419969A GB 1419969 A GB1419969 A GB 1419969A GB 5916472 A GB5916472 A GB 5916472A GB 5916472 A GB5916472 A GB 5916472A GB 1419969 A GB1419969 A GB 1419969A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cells
- chloroform
- immunostimulating agent
- saline
- solid residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003022 immunostimulating agent Substances 0.000 title abstract 5
- 229960001438 immunostimulant agent Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 12
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- 239000011780 sodium chloride Substances 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 3
- 230000003393 splenic effect Effects 0.000 abstract 3
- 241000186779 Listeria monocytogenes Species 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 2
- 239000011877 solvent mixture Substances 0.000 abstract 2
- 206010003445 Ascites Diseases 0.000 abstract 1
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 241000186216 Corynebacterium Species 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 abstract 1
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 abstract 1
- 241000607626 Vibrio cholerae Species 0.000 abstract 1
- 230000005587 bubbling Effects 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 229940102223 injectable solution Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7146520A FR2164510B1 (https=) | 1971-12-24 | 1971-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1419969A true GB1419969A (en) | 1975-12-31 |
Family
ID=9088030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5916472A Expired GB1419969A (en) | 1971-12-24 | 1972-12-21 | Immunostimulant agent compositions thereof and methods for their preparation |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4868729A (https=) |
| AR (1) | AR195897A1 (https=) |
| BE (1) | BE793260A (https=) |
| CA (1) | CA991543A (https=) |
| CS (1) | CS190380B2 (https=) |
| DE (1) | DE2262427C3 (https=) |
| DK (1) | DK137887B (https=) |
| ES (1) | ES410435A1 (https=) |
| FR (1) | FR2164510B1 (https=) |
| GB (1) | GB1419969A (https=) |
| IL (1) | IL41120A (https=) |
| NL (1) | NL7217588A (https=) |
| PL (1) | PL89687B1 (https=) |
| SU (1) | SU592333A3 (https=) |
| ZA (1) | ZA728959B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111642460A (zh) * | 2020-06-23 | 2020-09-11 | 山西省中医药研究院（山西省中医院） | 松果体损伤大鼠模型的构建方法 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2257266B1 (https=) | 1974-01-10 | 1977-07-01 | Pasteur Institut | |
| FR2287901A1 (fr) * | 1974-10-14 | 1976-05-14 | Pasteur Institut | Medicament immunostimulant contenant un derive d'ose ou de polyose phosphoryle |
| JPS5835121A (ja) * | 1981-08-20 | 1983-03-01 | ビラス・ヴィー・リクハイト | 免疫刺激性補助剤からなる抗原及び免疫療法におけるその使用 |
| CA1225592A (en) * | 1983-08-26 | 1987-08-18 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| IT1186793B (it) * | 1985-11-26 | 1987-12-16 | Sibar Srl | Frazione ottenuta da listeria monocytogenes avente attivita' terapeutica,procedimento per la sua preparazione e composioni farmaceutiche che la contengono |
| JPH02131433A (ja) * | 1988-11-11 | 1990-05-21 | Nisshin Flour Milling Co Ltd | 非特異的感染予防・治療剤 |
| EP3150323B1 (en) | 2015-09-30 | 2020-11-18 | Kabushiki Kaisha Toshiba | Laser processing apparatus, laser processing method and distance measurement method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU57091A1 (https=) * | 1968-10-15 | 1970-04-16 |
-
0
- BE BE793260D patent/BE793260A/xx not_active IP Right Cessation
-
1971
- 1971-12-24 FR FR7146520A patent/FR2164510B1/fr not_active Expired
-
1972
- 1972-12-19 IL IL41120A patent/IL41120A/xx unknown
- 1972-12-19 ZA ZA728959A patent/ZA728959B/xx unknown
- 1972-12-19 CA CA159,414A patent/CA991543A/en not_active Expired
- 1972-12-19 CS CS728757A patent/CS190380B2/cs unknown
- 1972-12-20 DE DE2262427A patent/DE2262427C3/de not_active Expired
- 1972-12-20 DK DK636172AA patent/DK137887B/da unknown
- 1972-12-21 GB GB5916472A patent/GB1419969A/en not_active Expired
- 1972-12-22 JP JP47129161A patent/JPS4868729A/ja active Pending
- 1972-12-22 NL NL7217588A patent/NL7217588A/xx not_active Application Discontinuation
- 1972-12-22 PL PL1972159796A patent/PL89687B1/pl unknown
- 1972-12-22 AR AR245808A patent/AR195897A1/es active
- 1972-12-22 SU SU721886347A patent/SU592333A3/ru active
- 1972-12-23 ES ES410435A patent/ES410435A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111642460A (zh) * | 2020-06-23 | 2020-09-11 | 山西省中医药研究院（山西省中医院） | 松果体损伤大鼠模型的构建方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL41120A (en) | 1975-12-31 |
| DE2262427B2 (de) | 1979-08-09 |
| NL7217588A (https=) | 1973-06-26 |
| SU592333A3 (ru) | 1978-02-05 |
| DE2262427A1 (de) | 1973-07-12 |
| ZA728959B (en) | 1973-09-26 |
| DE2262427C3 (de) | 1980-04-24 |
| FR2164510B1 (https=) | 1975-02-07 |
| CS190380B2 (en) | 1979-05-31 |
| DK137887B (da) | 1978-05-29 |
| DK137887C (https=) | 1978-10-16 |
| FR2164510A1 (https=) | 1973-08-03 |
| BE793260A (fr) | 1973-06-22 |
| ES410435A1 (es) | 1976-01-01 |
| PL89687B1 (en) | 1976-12-31 |
| JPS4868729A (https=) | 1973-09-19 |
| CA991543A (en) | 1976-06-22 |
| AR195897A1 (es) | 1973-11-15 |
| IL41120A0 (en) | 1973-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |