GB1417808A - 7a-cyano-17-hydroxy-3-oxo-17a-pregn-4-ene-21-carboxylic acid ypsilon-lactone and related compounds - Google Patents
7a-cyano-17-hydroxy-3-oxo-17a-pregn-4-ene-21-carboxylic acid ypsilon-lactone and related compoundsInfo
- Publication number
- GB1417808A GB1417808A GB5363273A GB5363273A GB1417808A GB 1417808 A GB1417808 A GB 1417808A GB 5363273 A GB5363273 A GB 5363273A GB 5363273 A GB5363273 A GB 5363273A GB 1417808 A GB1417808 A GB 1417808A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cyano
- hydroxy
- carboxylic acid
- alkali metal
- pregn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 4
- -1 alkaline earth metal cation Chemical class 0.000 abstract 4
- 230000007062 hydrolysis Effects 0.000 abstract 3
- 238000006460 hydrolysis reaction Methods 0.000 abstract 3
- 150000003431 steroids Chemical class 0.000 abstract 3
- HZNVUJQVZSTENZ-UHFFFAOYSA-N 2,3-dichloro-5,6-dicyano-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(C#N)=C(C#N)C1=O HZNVUJQVZSTENZ-UHFFFAOYSA-N 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- PCLIMKBDDGJMGD-UHFFFAOYSA-N N-bromosuccinimide Chemical compound BrN1C(=O)CCC1=O PCLIMKBDDGJMGD-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 150000003951 lactams Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000009935 nitrosation Effects 0.000 abstract 1
- 238000007034 nitrosation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31115772A | 1972-12-01 | 1972-12-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1417808A true GB1417808A (en) | 1975-12-17 |
Family
ID=23205662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5363273A Expired GB1417808A (en) | 1972-12-01 | 1973-11-19 | 7a-cyano-17-hydroxy-3-oxo-17a-pregn-4-ene-21-carboxylic acid ypsilon-lactone and related compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3773758A (https=) |
| JP (1) | JPS4986358A (https=) |
| CA (1) | CA1020543A (https=) |
| CH (1) | CH603691A5 (https=) |
| DE (1) | DE2357250A1 (https=) |
| ES (1) | ES420665A1 (https=) |
| FR (1) | FR2208665B1 (https=) |
| GB (1) | GB1417808A (https=) |
| NL (1) | NL7315822A (https=) |
| ZA (1) | ZA738806B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4211701A (en) * | 1979-04-13 | 1980-07-08 | The Upjohn Company | Spironolactone process |
| GB8916636D0 (en) * | 1989-07-20 | 1989-09-06 | Erba Carlo Spa | Steroid ethers |
| US5806111A (en) | 1996-04-12 | 1998-09-15 | Hill-Rom, Inc. | Stretcher controls |
| US6812358B2 (en) * | 2001-06-08 | 2004-11-02 | Bridge Organics Co. | Process for making estra-4,9(10)-diene steroids |
| US7810822B2 (en) | 2006-01-19 | 2010-10-12 | Hill-Rom Services, Inc. | Stretcher having hand actuated caster braking apparatus |
-
1972
- 1972-12-01 US US00311157A patent/US3773758A/en not_active Expired - Lifetime
-
1973
- 1973-11-09 CA CA185,462A patent/CA1020543A/en not_active Expired
- 1973-11-16 ZA ZA00738806A patent/ZA738806B/xx unknown
- 1973-11-16 DE DE2357250A patent/DE2357250A1/de not_active Withdrawn
- 1973-11-19 CH CH1618973A patent/CH603691A5/xx not_active IP Right Cessation
- 1973-11-19 ES ES420665A patent/ES420665A1/es not_active Expired
- 1973-11-19 NL NL7315822A patent/NL7315822A/xx not_active Application Discontinuation
- 1973-11-19 GB GB5363273A patent/GB1417808A/en not_active Expired
- 1973-11-19 FR FR7341131A patent/FR2208665B1/fr not_active Expired
- 1973-11-19 JP JP48130050A patent/JPS4986358A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA738806B (en) | 1975-01-29 |
| FR2208665A1 (https=) | 1974-06-28 |
| AU6241473A (en) | 1975-05-15 |
| ES420665A1 (es) | 1977-01-01 |
| NL7315822A (https=) | 1974-06-05 |
| FR2208665B1 (https=) | 1977-01-28 |
| DE2357250A1 (de) | 1974-06-06 |
| US3773758A (en) | 1973-11-20 |
| CH603691A5 (https=) | 1978-08-31 |
| CA1020543A (en) | 1977-11-08 |
| JPS4986358A (https=) | 1974-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |