GB1416934A - 3-aminoalkoxy-2,3-dihyddroquinobenzoxa or thia zepine derivatives - Google Patents
3-aminoalkoxy-2,3-dihyddroquinobenzoxa or thia zepine derivativesInfo
- Publication number
- GB1416934A GB1416934A GB269573A GB269573A GB1416934A GB 1416934 A GB1416934 A GB 1416934A GB 269573 A GB269573 A GB 269573A GB 269573 A GB269573 A GB 269573A GB 1416934 A GB1416934 A GB 1416934A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formula
- compound
- oxazepine
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004912 thiazepines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 13
- 150000001875 compounds Chemical class 0.000 abstract 10
- 239000002253 acid Substances 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- WXLCDTBTIVJDCE-UHFFFAOYSA-N 1,4-oxazepine Chemical compound O1C=CC=NC=C1 WXLCDTBTIVJDCE-UHFFFAOYSA-N 0.000 abstract 1
- UCOKCZAAOXYQCL-UHFFFAOYSA-N 2-(trifluoromethyl)-6,11-dihydrobenzo[c][1,5]benzoxazepine Chemical compound O1CC2=CC=CC=C2NC2=CC(C(F)(F)F)=CC=C21 UCOKCZAAOXYQCL-UHFFFAOYSA-N 0.000 abstract 1
- LGFYSURSCPVWRZ-UHFFFAOYSA-N 3-(2-chloro-6H-benzo[c][1,5]benzothiazepin-11-yl)propanoic acid Chemical compound ClC1=CC2=C(SCC3=C(N2CCC(=O)O)C=CC=C3)C=C1 LGFYSURSCPVWRZ-UHFFFAOYSA-N 0.000 abstract 1
- RXHRKRNYYVMLAG-UHFFFAOYSA-N 3-(2-chloro-6h-benzo[c][1,5]benzoxazepin-11-yl)propanoic acid Chemical compound C1OC2=CC=C(Cl)C=C2N(CCC(=O)O)C2=CC=CC=C21 RXHRKRNYYVMLAG-UHFFFAOYSA-N 0.000 abstract 1
- SXRCFYNNBQFNNA-UHFFFAOYSA-N 3-[2-(trifluoromethyl)-6h-benzo[c][1,5]benzoxazepin-11-yl]propanenitrile Chemical compound O1CC2=CC=CC=C2N(CCC#N)C2=CC(C(F)(F)F)=CC=C21 SXRCFYNNBQFNNA-UHFFFAOYSA-N 0.000 abstract 1
- YYMKVGWJHRRZNO-UHFFFAOYSA-N 3-[2-(trifluoromethyl)-6h-benzo[c][1,5]benzoxazepin-11-yl]propanoic acid Chemical compound C1OC2=CC=C(C(F)(F)F)C=C2N(CCC(=O)O)C2=CC=CC=C21 YYMKVGWJHRRZNO-UHFFFAOYSA-N 0.000 abstract 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 241000534944 Thia Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/18—[b, e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/14—[b, e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00222286A US3809698A (en) | 1972-01-31 | 1972-01-31 | 3-(aminoalkoxy)-2,3-dihydroquinobenzoxa or thia)zepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1416934A true GB1416934A (en) | 1975-12-10 |
Family
ID=22831636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB269573A Expired GB1416934A (en) | 1972-01-31 | 1973-01-18 | 3-aminoalkoxy-2,3-dihyddroquinobenzoxa or thia zepine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3809698A (enExample) |
| JP (1) | JPS4881898A (enExample) |
| DE (1) | DE2304729A1 (enExample) |
| FR (1) | FR2170080B1 (enExample) |
| GB (1) | GB1416934A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4171443A (en) * | 1978-05-08 | 1979-10-16 | Ayerst, Mckenna & Harrison Limited | 10B-Azafluoranthene derivatives and precursors thereof |
| US5488046A (en) * | 1993-11-03 | 1996-01-30 | G. D. Searle & Co. | Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
-
1972
- 1972-01-31 US US00222286A patent/US3809698A/en not_active Expired - Lifetime
-
1973
- 1973-01-18 GB GB269573A patent/GB1416934A/en not_active Expired
- 1973-01-31 JP JP48012830A patent/JPS4881898A/ja active Pending
- 1973-01-31 FR FR7303412A patent/FR2170080B1/fr not_active Expired
- 1973-01-31 DE DE2304729A patent/DE2304729A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2170080B1 (enExample) | 1975-10-10 |
| FR2170080A1 (enExample) | 1973-09-14 |
| JPS4881898A (enExample) | 1973-11-01 |
| DE2304729A1 (de) | 1973-08-09 |
| US3809698A (en) | 1974-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3729469A (en) | 4-(3-amino-2-hydroxypropoxy)-1,2,5-thiadiazole compounds | |
| KR880011123A (ko) | N- 벤즈히드릴- 치환된 헤테로사이클 유도체, 그의 제조방법 | |
| EP0377967A3 (en) | 9-Aza-3-(oxa/thia)-bicyclo[3,2,1]nonane derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | |
| YU52403A (sh) | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže | |
| DE3686248D1 (de) | Piperidinderivat, seine verwendung und diese enthaltende pharmazeutische zusammensetzung. | |
| BRPI0213243B8 (pt) | composto heterocíclico aromático contendo um anel oxazol, tiazol ou imidazol, ou um sal farmaceuticamente aceitável do mesmo, e, composição farmacêutica | |
| GB1170322A (en) | Substituted Dibenz[b,f][1,4]Oxazepin-11(10H)-Ones | |
| GB1265165A (enExample) | ||
| EP1295878A4 (en) | NEW PYRAZINE DERIVATIVES | |
| US4231930A (en) | 1-Substituted thiomethyltriazolobenzodiazepines | |
| GB1129116A (en) | Lactam derivatives | |
| CZ20012144A3 (cs) | Sulfonyloxazolaminy jakoľto terapeuticky účinné látky | |
| HU193333B (en) | Process for production of 2-amino-axazilons and medical preparatives containing thereof | |
| DE3889987D1 (de) | N-[(2-Oxopyrrolidin-1-yl)acetyl]piperazin-Derivate und Arzneimittel gegen senile Dementia. | |
| GB1416934A (en) | 3-aminoalkoxy-2,3-dihyddroquinobenzoxa or thia zepine derivatives | |
| GB1373537A (en) | Aminoalkoxy-benzylidene 2-h-benzothiazine-3-4h-ones and related compounds | |
| GB1437023A (en) | Substituted benzene-1,3-disulphonamides and process for their manufacture | |
| US3459748A (en) | Hydroxyalkylene-substituted benzoxazines and benzothiazines | |
| DE69634004D1 (de) | Verknüpfte polycyclische heterocyclische verbindungen | |
| ES2174077T3 (es) | Derivados de hidroxilamina antiisquemicos y composiciones farmaceuticas. | |
| GB1156781A (en) | New Heterocyclic Compounds | |
| US3562267A (en) | Derivatives of 3-(5-nitrofur-2-yl)-5-aminoisoxazoles | |
| US3454576A (en) | 2-aminofuro (2,3-d) thiazoles and production thereof | |
| US3748328A (en) | 2-amidocephalosporins | |
| FI955933A0 (fi) | Abeo-ergoliinijohdannaiset 5HT1A-ligandeina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |