GB1413630A - Process for the manufacture of 14, 18-epoxyethano-iminosteroids - Google Patents
Process for the manufacture of 14, 18-epoxyethano-iminosteroidsInfo
- Publication number
- GB1413630A GB1413630A GB2583173A GB2583173A GB1413630A GB 1413630 A GB1413630 A GB 1413630A GB 2583173 A GB2583173 A GB 2583173A GB 2583173 A GB2583173 A GB 2583173A GB 1413630 A GB1413630 A GB 1413630A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- free
- esterified
- etherified
- steroids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 8
- 150000003431 steroids Chemical class 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- -1 C2U Steroids Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052987 metal hydride Inorganic materials 0.000 abstract 2
- 150000004681 metal hydrides Chemical class 0.000 abstract 2
- CKTHNEHZDHNACR-UHFFFAOYSA-N 14-(1-hydroxyethyl)-2,11a-dimethyldodecahydro-5bh-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepine-9,12(8h)-diol Chemical compound O1CCN(C)CC23C(C(O)C)=CCC31C1CCC(C3)C4(C)CCC3(O)OC41C(O)C2 CKTHNEHZDHNACR-UHFFFAOYSA-N 0.000 abstract 1
- ZKCSFQZJDZSMCH-IGLVISNFSA-N 962fmm1isf Chemical compound O1CCN(C)C[C@]23C([C@@H](O)C)=CC[C@]31C1=CC[C@H](C3)[C@]4(C)CC[C@@]3(O)O[C@@]41[C@H](O)C2 ZKCSFQZJDZSMCH-IGLVISNFSA-N 0.000 abstract 1
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- 241000208011 Digitalis Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- ZKCSFQZJDZSMCH-UHFFFAOYSA-N batrachotoxinin-A Natural products O1CCN(C)CC23C(C(O)C)=CCC31C1=CCC(C3)C4(C)CCC3(O)OC41C(O)C2 ZKCSFQZJDZSMCH-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH796772 | 1972-05-30 | ||
| CH108073 | 1973-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1413630A true GB1413630A (en) | 1975-11-12 |
Family
ID=25686590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2583173A Expired GB1413630A (en) | 1972-05-30 | 1973-05-30 | Process for the manufacture of 14, 18-epoxyethano-iminosteroids |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4961186A (enrdf_load_stackoverflow) |
| DE (1) | DE2325873A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2186260B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1413630A (enrdf_load_stackoverflow) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1768162A1 (de) * | 1968-04-06 | 1971-09-30 | Schering Ag | Neue 18-Nor-14ss-pregnano-[13,14-f]-hexahydro-1,4-oxazepine |
| CH576488A5 (enrdf_load_stackoverflow) * | 1969-06-13 | 1976-06-15 | Ciba Geigy Ag | |
| BE757924A (fr) * | 1969-10-24 | 1971-04-01 | Geigy Ag J R | Composes steroidiques a noyau heterocyclique azote, leur preparation etmedicaments contenant de tels composes |
| CH583253A5 (enrdf_load_stackoverflow) * | 1970-07-24 | 1976-12-31 | Ciba Geigy Ag |
-
1973
- 1973-05-22 DE DE19732325873 patent/DE2325873A1/de active Pending
- 1973-05-30 FR FR7319693A patent/FR2186260B1/fr not_active Expired
- 1973-05-30 JP JP48061426A patent/JPS4961186A/ja active Pending
- 1973-05-30 GB GB2583173A patent/GB1413630A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4961186A (enrdf_load_stackoverflow) | 1974-06-13 |
| FR2186260B1 (enrdf_load_stackoverflow) | 1977-04-15 |
| FR2186260A1 (enrdf_load_stackoverflow) | 1974-01-11 |
| DE2325873A1 (de) | 1973-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1254626A (en) | New 19-hydroxy-3-aza-a-homo-steroids and a process for their manufacture | |
| GB1413630A (en) | Process for the manufacture of 14, 18-epoxyethano-iminosteroids | |
| DE2529969A1 (de) | Neue von testosteron abgeleitete haptene, verfahren zu ihrer herstellung und ihre verwendung bei der herstellung von antigenen | |
| GB1472922A (en) | Pregnanoic acid derivatives | |
| IE41233B1 (en) | Novel 11-substituted steroids of the estrane series | |
| GB1450807A (en) | Cardenolide glycosides and process for their manufacture | |
| GB1530615A (en) | 15,16-methylene-steroids of the pregnane series | |
| GB1514621A (en) | 13-ethynyl-and 13-(2-halovinyl)-steroids and their preparation | |
| GB1140642A (en) | 17--cyanoethynyl-steroids | |
| US3242169A (en) | 6alpha-dimethylaminomethyl-3-oxo-delta4-steroids and method for producing same | |
| US3318789A (en) | Process for the manufacture of 19-nor-steroids | |
| GB1282520A (en) | 06-methyl-steroids and processes for their preparation | |
| GB1255950A (en) | 08-methylene-steroids and process for their manufacture | |
| GB1308656A (en) | Cardadienolide derivatives and process for their manufacture | |
| GB1051580A (enrdf_load_stackoverflow) | ||
| GB1208884A (en) | Tetrahydropyranylethers of steroids and process for their manufacture | |
| US3275663A (en) | 2-hydroxymethylene testosterone derivatives | |
| US3053862A (en) | 3-unsubstituted steroids of the pregnane series | |
| GB1333036A (en) | 3-oxo-a-nor-b-homo-oestra-5-10-6-dienes and a process for their manufacture | |
| GB1276743A (en) | Aldehydes of the pregnane series and process for their manufacture | |
| GB1371798A (en) | Cardenolide derivatives and a process for their manufacture | |
| GB1236474A (en) | 3-oxo-a,19-bis-nor-b-homo-steroid-5(10)-enes and process for their manufacture | |
| GB1363674A (en) | Cardenolide derivatives and a process for their manufacture | |
| GB1240698A (en) | Methylenation process and reagent | |
| GB1176232A (en) | Improvements in or relating to 6,7-Ethylene and 6,7-Substituted Ehtylene Derivatives of the Pregnane Series |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |