GB1411350A - Substituted indole compound process for the preparation and therapeutic compositions containing it - Google Patents
Substituted indole compound process for the preparation and therapeutic compositions containing itInfo
- Publication number
- GB1411350A GB1411350A GB3343573A GB3343573A GB1411350A GB 1411350 A GB1411350 A GB 1411350A GB 3343573 A GB3343573 A GB 3343573A GB 3343573 A GB3343573 A GB 3343573A GB 1411350 A GB1411350 A GB 1411350A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- compositions containing
- therapeutic compositions
- substituted indole
- indole compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2234651A DE2234651C3 (de) | 1972-07-14 | 1972-07-14 | Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1411350A true GB1411350A (en) | 1975-10-22 |
Family
ID=5850654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3343573A Expired GB1411350A (en) | 1972-07-14 | 1973-07-13 | Substituted indole compound process for the preparation and therapeutic compositions containing it |
Country Status (27)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456611A (en) * | 1981-02-02 | 1984-06-26 | Laboratoires Panmedica | Derivatives of 2-[3-(3-indoly)2-amino propionyloxy] acetic acid, and seritoning increasing use thereof |
| US4459415A (en) * | 1982-02-26 | 1984-07-10 | Troponwerke Gmbh & Co. Kg | Process for the preparation of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetoxyacetic acid |
| US4503237A (en) * | 1981-12-28 | 1985-03-05 | Siegfried Aktiengesellschaft | Method for the production of acemetacin |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1531546A (en) * | 1976-05-19 | 1978-11-08 | Pierrel Spa | Anti-inflammatory indole derivative |
| JPS52156862A (en) * | 1976-06-22 | 1977-12-27 | Hisamitsu Pharmaceut Co Inc | Novel indoleacetic acid ester derivatives |
| CS190723B1 (en) * | 1976-06-30 | 1979-06-29 | Ludmila Fisnerova | 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same |
| GB1587070A (en) * | 1977-06-02 | 1981-03-25 | Sterwin Ag | Pharmacologically-active 4-acetamidophenyl a-(2-methyl-ind(en/ol)-3-yl)-acetates processes for their preparation and pharmaceutical composition incorporating them |
| DE2735537A1 (de) * | 1977-08-06 | 1979-02-22 | Troponwerke Gmbh & Co Kg | Indolacetoxyacetylaminosaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE2943126A1 (de) * | 1979-10-25 | 1981-05-14 | Troponwerke GmbH & Co KG, 5000 Köln | Laevulinoyloxyessigsaeure und verfahren zu ihrer herstellung |
| DE2943127A1 (de) * | 1979-10-25 | 1981-05-14 | Troponwerke GmbH & Co KG, 5000 Köln | (1-(4-chlorbenzoyl)-methoxy-2-methyl-3-indol) -acetoxyessigsaeuremonohydrat, verfahren zur herstellung sowie dessen verwendung in arzneimitteln |
| DE2943125A1 (de) * | 1979-10-25 | 1981-05-14 | Troponwerke GmbH & Co KG, 5000 Köln | Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure |
| DE3206886A1 (de) * | 1982-02-26 | 1983-10-27 | Troponwerke GmbH & Co KG, 5000 Köln | Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3- indolacetoxyessigsaeure |
| JPS59204172A (ja) * | 1983-04-28 | 1984-11-19 | Kowa Co | アセメタシンの製造法 |
| JPS60112760A (ja) * | 1983-11-18 | 1985-06-19 | Green Cross Corp:The | インド−ル酢酸誘導体及びその脂肪乳剤 |
| WO2006099677A1 (en) * | 2005-03-24 | 2006-09-28 | Medical Therapies Limited | Metal complexes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3775429A (en) * | 1966-10-13 | 1973-11-27 | Merck & Co Inc | Process for preparing 3-indolyl acetic acids |
| US3518280A (en) * | 1968-06-27 | 1970-06-30 | Merck & Co Inc | 1-p-chlorobenzoyl-2-methyl-5-methoxyindole-3-malonic acid derivatives |
-
1972
- 1972-07-14 DE DE2234651A patent/DE2234651C3/de not_active Expired
-
1973
- 1973-06-28 US US374615A patent/US3910952A/en not_active Expired - Lifetime
- 1973-07-06 CS CS7300004899A patent/CS179418B2/cs unknown
- 1973-07-06 SU SU1942666A patent/SU474980A3/ru active
- 1973-07-09 YU YU1858/73A patent/YU35353B/xx unknown
- 1973-07-11 RO RO7375429A patent/RO64477A/ro unknown
- 1973-07-11 PL PL1973163991A patent/PL91610B1/pl unknown
- 1973-07-12 CA CA176,315A patent/CA979893A/en not_active Expired
- 1973-07-12 AU AU58011/73A patent/AU473000B2/en not_active Expired
- 1973-07-12 ZA ZA734735A patent/ZA734735B/xx unknown
- 1973-07-12 DD DD172231A patent/DD107917A5/xx unknown
- 1973-07-12 HU HUTO961A patent/HU165158B/hu unknown
- 1973-07-12 IL IL42728A patent/IL42728A/en unknown
- 1973-07-12 IE IE1181/73A patent/IE38039B1/xx unknown
- 1973-07-12 FI FI2213/73A patent/FI56833C/fi active
- 1973-07-13 GB GB3343573A patent/GB1411350A/en not_active Expired
- 1973-07-13 SE SE7309900A patent/SE380522B/xx unknown
- 1973-07-13 AR AR249094A patent/AR197345A1/es active
- 1973-07-13 BE BE133498A patent/BE802358A/xx not_active IP Right Cessation
- 1973-07-13 CH CH1026673A patent/CH582141A5/xx not_active IP Right Cessation
- 1973-07-13 JP JP48079201A patent/JPS5147708B2/ja not_active Expired
- 1973-07-13 ES ES416877A patent/ES416877A1/es not_active Expired
- 1973-07-13 OA OA54967A patent/OA04546A/xx unknown
- 1973-07-13 FR FR7325791A patent/FR2192828B1/fr not_active Expired
- 1973-07-13 AT AT619473A patent/AT324322B/de not_active IP Right Cessation
- 1973-07-13 NL NLAANVRAGE7309811,A patent/NL173748C/xx not_active IP Right Cessation
- 1973-07-13 DK DK389973A patent/DK134400C/da not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456611A (en) * | 1981-02-02 | 1984-06-26 | Laboratoires Panmedica | Derivatives of 2-[3-(3-indoly)2-amino propionyloxy] acetic acid, and seritoning increasing use thereof |
| US4503237A (en) * | 1981-12-28 | 1985-03-05 | Siegfried Aktiengesellschaft | Method for the production of acemetacin |
| US4459415A (en) * | 1982-02-26 | 1984-07-10 | Troponwerke Gmbh & Co. Kg | Process for the preparation of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetoxyacetic acid |
Also Published As
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| Publication | Publication Date | Title |
|---|---|---|
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930712 |