GB1410236A - Procedure for obtaining ampicillin - Google Patents

Procedure for obtaining ampicillin

Info

Publication number
GB1410236A
GB1410236A GB4691272A GB4691272A GB1410236A GB 1410236 A GB1410236 A GB 1410236A GB 4691272 A GB4691272 A GB 4691272A GB 4691272 A GB4691272 A GB 4691272A GB 1410236 A GB1410236 A GB 1410236A
Authority
GB
United Kingdom
Prior art keywords
ampicillin
procedure
group
galenika
benzylpenicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4691272A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GALENIKA PHARMACEUTICAL
Original Assignee
GALENIKA PHARMACEUTICAL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GALENIKA PHARMACEUTICAL filed Critical GALENIKA PHARMACEUTICAL
Publication of GB1410236A publication Critical patent/GB1410236A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1410236 Ampicillin GALENIKA PHARMACEUTICAL & CHEMICAL INDUSTRY 11 Oct 1972 [17 April 1972] 46912/72 Heading C2C Ampicillin, especially ampicillin trihydrate, is prepared by treating a protected imino ether of benzylpenicillin of the formula wherein R 1 is an alkyl group and R 2 , which protects the carboxyl group, is a readily hydrolysable group such as the residue of an aliphatic or aromatic carboxylic or dicarboxylic acid, or of an aromatic sulphonic acid (e.g. propionic, acetic butyric, valeric, benzoic, succinic and p-toluenesulphonic acid residues); in two successive steps with (a) water and (b) phenylglycine chloride hydrochloride, the treatment (b) being carried out in the presence of an organic solvent.
GB4691272A 1972-04-17 1972-10-11 Procedure for obtaining ampicillin Expired GB1410236A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU103272A YU34297B (en) 1972-04-17 1972-04-17 Process for obtaining ampicillin

Publications (1)

Publication Number Publication Date
GB1410236A true GB1410236A (en) 1975-10-15

Family

ID=25552491

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4691272A Expired GB1410236A (en) 1972-04-17 1972-10-11 Procedure for obtaining ampicillin

Country Status (8)

Country Link
CH (1) CH574963A5 (en)
CS (1) CS182232B2 (en)
DE (1) DE2255846A1 (en)
FR (1) FR2180632B1 (en)
GB (1) GB1410236A (en)
HU (1) HU171899B (en)
PL (1) PL90348B1 (en)
YU (1) YU34297B (en)

Also Published As

Publication number Publication date
YU34297B (en) 1979-04-30
FR2180632A1 (en) 1973-11-30
PL90348B1 (en) 1977-01-31
CS182232B2 (en) 1978-04-28
HU171899B (en) 1978-04-28
FR2180632B1 (en) 1976-08-20
CH574963A5 (en) 1976-04-30
DE2255846A1 (en) 1973-10-31
YU103272A (en) 1978-10-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee