GB1398724A - Disubstituted xanthone carboxylic acid compounds - Google Patents
Disubstituted xanthone carboxylic acid compoundsInfo
- Publication number
- GB1398724A GB1398724A GB4737374A GB4737374A GB1398724A GB 1398724 A GB1398724 A GB 1398724A GB 4737374 A GB4737374 A GB 4737374A GB 4737374 A GB4737374 A GB 4737374A GB 1398724 A GB1398724 A GB 1398724A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- product
- carboxylic acid
- cycloalkyl
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WNKRYYFWYMHTGV-UHFFFAOYSA-N 9-oxoxanthene-1-carboxylic acid Chemical class O1C2=CC=CC=C2C(=O)C2=C1C=CC=C2C(=O)O WNKRYYFWYMHTGV-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 230000003301 hydrolyzing effect Effects 0.000 abstract 5
- YMWAOMLAFRHRFF-UHFFFAOYSA-N 2,4-bis(sulfanyl)xanthen-9-one Chemical compound SC1=C2OC=3C=CC=CC=3C(C2=CC(=C1)S)=O YMWAOMLAFRHRFF-UHFFFAOYSA-N 0.000 abstract 3
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 abstract 2
- MNVMYTVDDOXZLS-UHFFFAOYSA-N 4-methoxyguaiacol Natural products COC1=CC=C(O)C(OC)=C1 MNVMYTVDDOXZLS-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- BERDEBHAJNAUOM-UHFFFAOYSA-N copper(I) oxide Inorganic materials [Cu]O[Cu] BERDEBHAJNAUOM-UHFFFAOYSA-N 0.000 abstract 1
- KRFJLUBVMFXRPN-UHFFFAOYSA-N cuprous oxide Chemical compound [O-2].[Cu+].[Cu+] KRFJLUBVMFXRPN-UHFFFAOYSA-N 0.000 abstract 1
- 229940112669 cuprous oxide Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 abstract 1
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 150000004965 peroxy acids Chemical class 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000050 smooth muscle relaxant Substances 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
- -1 xanthene compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00217287A US3849565A (en) | 1972-01-12 | 1972-01-12 | Disubstituted xanthone carboxylic acid compounds for inhibiting asthma |
| US25985272A | 1972-06-05 | 1972-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1398724A true GB1398724A (en) | 1975-06-25 |
Family
ID=26911795
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4737374A Expired GB1398724A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
| GB4736974A Expired GB1398723A (en) | 1972-01-12 | 1972-07-12 | Chlorosulphonyl-xanthone-2-carboxylic acids |
| GB3253472A Expired GB1398722A (en) | 1972-01-12 | 1972-07-12 | Disbustistuted xanthone carboxylic acid compounds |
| GB4737574A Expired GB1398725A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4736974A Expired GB1398723A (en) | 1972-01-12 | 1972-07-12 | Chlorosulphonyl-xanthone-2-carboxylic acids |
| GB3253472A Expired GB1398722A (en) | 1972-01-12 | 1972-07-12 | Disbustistuted xanthone carboxylic acid compounds |
| GB4737574A Expired GB1398725A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
Country Status (15)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4242267A (en) | 1980-02-04 | 1980-12-30 | Roussel Uclaf | Process for preparing 5-alkyl-7-(S-alkyl-sulfonimidoyl)-xanthone-2-carboxylic acids |
| BE1010719A3 (nl) | 1996-10-28 | 1998-12-01 | Dsm Nv | Werkwijze voor de bereiding van hydroxylammoniumzouten. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759292A (fr) * | 1969-11-27 | 1971-05-24 | Allen & Hanburys Ltd | Derives de xanthone, leur preparation et leur emploi |
-
0
- BE BE793749D patent/BE793749A/xx unknown
-
1972
- 1972-07-12 GB GB4737374A patent/GB1398724A/en not_active Expired
- 1972-07-12 FR FR7225352A patent/FR2167490B1/fr not_active Expired
- 1972-07-12 IL IL39891A patent/IL39891A/en unknown
- 1972-07-12 GB GB4736974A patent/GB1398723A/en not_active Expired
- 1972-07-12 GB GB3253472A patent/GB1398722A/en not_active Expired
- 1972-07-12 SE SE7209197A patent/SE387946B/xx unknown
- 1972-07-12 CH CH1045772A patent/CH588483A5/xx not_active IP Right Cessation
- 1972-07-12 GB GB4737574A patent/GB1398725A/en not_active Expired
- 1972-07-12 JP JP6985272A patent/JPS5347107B2/ja not_active Expired
- 1972-07-12 AT AT860574*7A patent/AT327897B/de not_active IP Right Cessation
- 1972-07-12 NL NL7209629A patent/NL7209629A/xx not_active Application Discontinuation
- 1972-07-12 CH CH1177376A patent/CH586692A5/xx not_active IP Right Cessation
- 1972-07-12 AR AR243026A patent/AR202889A1/es active
- 1972-07-12 CH CH1177576A patent/CH586694A5/xx not_active IP Right Cessation
- 1972-07-12 AU AU44458/72A patent/AU465362B2/en not_active Expired
- 1972-07-12 CH CH1177476A patent/CH586693A5/xx not_active IP Right Cessation
- 1972-07-12 AT AT860674*7A patent/AT327898B/de not_active IP Right Cessation
- 1972-07-12 DE DE19722265054 patent/DE2265054A1/de active Pending
- 1972-07-12 ES ES404790A patent/ES404790A1/es not_active Expired
- 1972-07-12 NO NO2495/72A patent/NO137199C/no unknown
-
1973
- 1973-01-01 AR AR249068A patent/AR208274A1/es active
- 1973-03-19 NO NO1092/73A patent/NO137204C/no unknown
- 1973-03-19 NO NO1091/73A patent/NO137203C/no unknown
- 1973-07-13 AR AR249071A patent/AR202188A1/es active
-
1974
- 1974-11-14 CA CA213,708A patent/CA1014167A/en not_active Expired
-
1975
- 1975-01-01 AR AR259804A patent/AR206878A1/es active
- 1975-01-01 AR AR258182A patent/AR206919A1/es active
- 1975-01-03 ES ES433555A patent/ES433555A1/es not_active Expired
- 1975-01-03 ES ES433553A patent/ES433553A1/es not_active Expired
- 1975-01-03 ES ES433554A patent/ES433554A1/es not_active Expired
- 1975-01-03 ES ES433552A patent/ES433552A1/es not_active Expired
- 1975-02-26 ES ES435108A patent/ES435108A1/es not_active Expired
-
1977
- 1977-06-01 JP JP6457177A patent/JPS5350171A/ja active Pending
- 1977-06-01 JP JP6457277A patent/JPS5350172A/ja active Pending
- 1977-06-01 JP JP6457077A patent/JPS5350170A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |