GB1398725A - Disubstituted xanthone carboxylic acid compounds - Google Patents
Disubstituted xanthone carboxylic acid compoundsInfo
- Publication number
- GB1398725A GB1398725A GB4737574A GB4737574A GB1398725A GB 1398725 A GB1398725 A GB 1398725A GB 4737574 A GB4737574 A GB 4737574A GB 4737574 A GB4737574 A GB 4737574A GB 1398725 A GB1398725 A GB 1398725A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- carboxylic acid
- acid compounds
- cycloalkoxy
- amides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1398725 Disubstituted xanthone carboxylic acid compounds SYNTEX (USA) Inc 12 July 1972 [12 Jan 1972 5 June 1972] 47375/74 Divided out of 1398722 Heading C2C The invention comprises compounds of the formula wherein either the X groups are identical and are -SO 2 R groups where R is OH, NH 2 or mono - or di-(C 1 -C 6 )alkylamino; or one X group is C 1 -C 5 alkyl or alkoxy or C 3 -C 5 cycloalkyl or cycloalkoxy and the other X group is -SO 2 R as above; and non-toxic esters, amides and salts thereof. They may be obtained by treating a compound of one of the formulµ wherein R<SP>20</SP> is (C 1 -C 5 ) alkyl or alkoxy, or (C 3 -C 5 ) cycloalkyl or cycloalkoxy; with an inorganic base other than NH 3 or with NH 3 or a mono- or di-alkylamine; optionally converting the products into their non-toxic esters, amides or salts. Examples are given for the production of the compounds. Pharmaceutical compositions comprise the compounds of Formula I above which may be administered orally, topically, parenterally or by inhalation in conventional forms, optionally together with other pharmaceutical agents. They are useful for inhibiting the effects of allergic reactions, also as smooth muscle relaxants and as vasodilators.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00217287A US3849565A (en) | 1972-01-12 | 1972-01-12 | Disubstituted xanthone carboxylic acid compounds for inhibiting asthma |
| US25985272A | 1972-06-05 | 1972-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1398725A true GB1398725A (en) | 1975-06-25 |
Family
ID=26911795
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3253472A Expired GB1398722A (en) | 1972-01-12 | 1972-07-12 | Disbustistuted xanthone carboxylic acid compounds |
| GB4737374A Expired GB1398724A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
| GB4736974A Expired GB1398723A (en) | 1972-01-12 | 1972-07-12 | Chlorosulphonyl-xanthone-2-carboxylic acids |
| GB4737574A Expired GB1398725A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3253472A Expired GB1398722A (en) | 1972-01-12 | 1972-07-12 | Disbustistuted xanthone carboxylic acid compounds |
| GB4737374A Expired GB1398724A (en) | 1972-01-12 | 1972-07-12 | Disubstituted xanthone carboxylic acid compounds |
| GB4736974A Expired GB1398723A (en) | 1972-01-12 | 1972-07-12 | Chlorosulphonyl-xanthone-2-carboxylic acids |
Country Status (15)
| Country | Link |
|---|---|
| JP (4) | JPS5347107B2 (en) |
| AR (5) | AR202889A1 (en) |
| AT (2) | AT327898B (en) |
| AU (1) | AU465362B2 (en) |
| BE (1) | BE793749A (en) |
| CA (1) | CA1014167A (en) |
| CH (4) | CH586694A5 (en) |
| DE (1) | DE2265054A1 (en) |
| ES (6) | ES404790A1 (en) |
| FR (1) | FR2167490B1 (en) |
| GB (4) | GB1398722A (en) |
| IL (1) | IL39891A (en) |
| NL (1) | NL7209629A (en) |
| NO (3) | NO137199C (en) |
| SE (1) | SE387946B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221328B1 (en) | 1996-10-28 | 2001-04-24 | Dsm N.V. | Process for preparing hydroxylammonium salts |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759292A (en) * | 1969-11-27 | 1971-05-24 | Allen & Hanburys Ltd | XANTHONE DERIVATIVES, THEIR PREPARATION AND THEIR USE |
-
0
- BE BE793749D patent/BE793749A/en unknown
-
1972
- 1972-07-12 AT AT860674*7A patent/AT327898B/en not_active IP Right Cessation
- 1972-07-12 DE DE19722265054 patent/DE2265054A1/en active Pending
- 1972-07-12 GB GB3253472A patent/GB1398722A/en not_active Expired
- 1972-07-12 ES ES404790A patent/ES404790A1/en not_active Expired
- 1972-07-12 GB GB4737374A patent/GB1398724A/en not_active Expired
- 1972-07-12 AR AR243026A patent/AR202889A1/en active
- 1972-07-12 GB GB4736974A patent/GB1398723A/en not_active Expired
- 1972-07-12 CH CH1177576A patent/CH586694A5/xx not_active IP Right Cessation
- 1972-07-12 GB GB4737574A patent/GB1398725A/en not_active Expired
- 1972-07-12 NL NL7209629A patent/NL7209629A/xx not_active Application Discontinuation
- 1972-07-12 FR FR7225352A patent/FR2167490B1/fr not_active Expired
- 1972-07-12 AU AU44458/72A patent/AU465362B2/en not_active Expired
- 1972-07-12 JP JP6985272A patent/JPS5347107B2/ja not_active Expired
- 1972-07-12 NO NO2495/72A patent/NO137199C/en unknown
- 1972-07-12 CH CH1045772A patent/CH588483A5/xx not_active IP Right Cessation
- 1972-07-12 AT AT860574*7A patent/AT327897B/en not_active IP Right Cessation
- 1972-07-12 CH CH1177476A patent/CH586693A5/xx not_active IP Right Cessation
- 1972-07-12 IL IL39891A patent/IL39891A/en unknown
- 1972-07-12 CH CH1177376A patent/CH586692A5/xx not_active IP Right Cessation
- 1972-07-12 SE SE7209197A patent/SE387946B/en unknown
-
1973
- 1973-01-01 AR AR249068A patent/AR208274A1/en active
- 1973-03-19 NO NO1091/73A patent/NO137203C/en unknown
- 1973-03-19 NO NO1092/73A patent/NO137204C/en unknown
- 1973-07-13 AR AR249071A patent/AR202188A1/en active
-
1974
- 1974-11-14 CA CA213,708A patent/CA1014167A/en not_active Expired
-
1975
- 1975-01-01 AR AR258182A patent/AR206919A1/en active
- 1975-01-01 AR AR259804A patent/AR206878A1/en active
- 1975-01-03 ES ES433554A patent/ES433554A1/en not_active Expired
- 1975-01-03 ES ES433552A patent/ES433552A1/en not_active Expired
- 1975-01-03 ES ES433553A patent/ES433553A1/en not_active Expired
- 1975-01-03 ES ES433555A patent/ES433555A1/en not_active Expired
- 1975-02-26 ES ES435108A patent/ES435108A1/en not_active Expired
-
1977
- 1977-06-01 JP JP6457177A patent/JPS5350171A/en active Pending
- 1977-06-01 JP JP6457077A patent/JPS5350170A/en active Pending
- 1977-06-01 JP JP6457277A patent/JPS5350172A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221328B1 (en) | 1996-10-28 | 2001-04-24 | Dsm N.V. | Process for preparing hydroxylammonium salts |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |