GB1397732A - Stabilized choline salicylate compounds - Google Patents
Stabilized choline salicylate compoundsInfo
- Publication number
- GB1397732A GB1397732A GB3494171A GB3494171A GB1397732A GB 1397732 A GB1397732 A GB 1397732A GB 3494171 A GB3494171 A GB 3494171A GB 3494171 A GB3494171 A GB 3494171A GB 1397732 A GB1397732 A GB 1397732A
- Authority
- GB
- United Kingdom
- Prior art keywords
- choline salicylate
- july
- alkali metal
- salicylate
- salicylate compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UDKCHVLMFQVBAA-UHFFFAOYSA-M Choline salicylate Chemical class C[N+](C)(C)CCO.OC1=CC=CC=C1C([O-])=O UDKCHVLMFQVBAA-UHFFFAOYSA-M 0.000 title abstract 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 2
- GRWZHXKQBITJKP-UHFFFAOYSA-N dithionous acid Chemical class OS(=O)S(O)=O GRWZHXKQBITJKP-UHFFFAOYSA-N 0.000 abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical group OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910001413 alkali metal ion Inorganic materials 0.000 abstract 1
- -1 alkali metal sulphites Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229960002688 choline salicylate Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- WBZKQQHYRPRKNJ-UHFFFAOYSA-L disulfite Chemical group [O-]S(=O)S([O-])(=O)=O WBZKQQHYRPRKNJ-UHFFFAOYSA-L 0.000 abstract 1
- GRWZHXKQBITJKP-UHFFFAOYSA-L dithionite(2-) Chemical group [O-]S(=O)S([O-])=O GRWZHXKQBITJKP-UHFFFAOYSA-L 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960001860 salicylate Drugs 0.000 abstract 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical group [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 abstract 1
- 235000010269 sulphur dioxide Nutrition 0.000 abstract 1
- 239000004291 sulphur dioxide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3494171A GB1397732A (en) | 1971-07-26 | 1971-07-26 | Stabilized choline salicylate compounds |
| US00237927A US3855282A (en) | 1971-07-26 | 1972-03-24 | Stabilized choline salicylate compounds |
| ZA722798A ZA722798B (en) | 1971-07-26 | 1972-04-25 | Stabilized choline salicylate compounds |
| ES402541A ES402541A1 (es) | 1971-07-26 | 1972-05-09 | Un metodo para la preparacion de compuestos de salicilato de colina que contienen sulfito. |
| DE2222902A DE2222902C2 (de) | 1971-07-26 | 1972-05-10 | Cholin-salicylat-Alkalimetall-dithionit bzw. -sulfit und deren Verwendung |
| AU42323/72A AU461584B2 (en) | 1971-07-26 | 1972-05-16 | Stabilized choline salicylate compounds |
| CH962572A CH590816A5 (https=) | 1971-07-26 | 1972-06-27 | |
| CA146,186A CA1009664A (en) | 1971-07-26 | 1972-06-30 | Stabilized choline salicylate compounds |
| FR7226732A FR2147170B1 (https=) | 1971-07-26 | 1972-07-25 | |
| DK368072A DK145540C (da) | 1971-07-26 | 1972-07-25 | Fremgangsmaade til fremstilling af eventuelt i oploest form foreliggende cholinsalicylatsulfitholdige forbindelser |
| NO2651/72A NO146137C (no) | 1971-07-26 | 1972-07-25 | Fremgangsmaate ved fremstilling av farvestabiliserte, terapeutisk aktive salicylatforbindelser |
| IL40542A IL40542A (en) | 1971-07-26 | 1972-10-11 | Stabilized compounds of choline salicylate their preparation and pharmaceutical compositions containing them |
| IN2052/72A IN139346B (https=) | 1971-07-26 | 1972-12-04 | |
| ES410123A ES410123A1 (es) | 1971-07-26 | 1972-12-28 | Un metodo para suprimir la formacion de color en una formu-lacion farmaceutica que contiene salicilato. |
| US05/625,783 US4001311A (en) | 1971-07-24 | 1975-10-24 | Stabilized choline salicylate compounds |
| US05/753,396 US4098813A (en) | 1971-07-24 | 1976-12-22 | Preparation of alkali metal choline salicylate salt complexes |
| US05/880,840 US4147776A (en) | 1971-07-24 | 1978-02-23 | Stabilized choline salicylate compounds |
| DK83879A DK146735C (da) | 1971-07-26 | 1979-02-27 | Fremgangsmaade samt middel til at undertrykke farvedannelse i en salicylatholdig farmaceutisk formulering |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3494171A GB1397732A (en) | 1971-07-26 | 1971-07-26 | Stabilized choline salicylate compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1397732A true GB1397732A (en) | 1975-06-18 |
Family
ID=10371855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3494171A Expired GB1397732A (en) | 1971-07-24 | 1971-07-26 | Stabilized choline salicylate compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3855282A (https=) |
| AU (1) | AU461584B2 (https=) |
| CA (1) | CA1009664A (https=) |
| CH (1) | CH590816A5 (https=) |
| DE (1) | DE2222902C2 (https=) |
| DK (1) | DK145540C (https=) |
| ES (2) | ES402541A1 (https=) |
| FR (1) | FR2147170B1 (https=) |
| GB (1) | GB1397732A (https=) |
| IL (1) | IL40542A (https=) |
| IN (1) | IN139346B (https=) |
| NO (1) | NO146137C (https=) |
| ZA (1) | ZA722798B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0051962A3 (en) * | 1980-11-05 | 1982-09-29 | Sumitomo Chemical Company, Limited | Pharmaceutical composition comprising 4-carbamoyl-imidazolium-5-oleate |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4098813A (en) * | 1971-07-24 | 1978-07-04 | Mundipharma Ag | Preparation of alkali metal choline salicylate salt complexes |
| US5043168A (en) * | 1990-04-26 | 1991-08-27 | Sidmak Laboratories, Inc. | Solid choline magnesium salicylate composition and method of preparing same |
| DE10227793A1 (de) * | 2002-06-21 | 2004-01-08 | Basf Ag | Stabilisierte Cholinascorbat enthaltende Zusammensetzung |
| EP1781594A1 (en) * | 2004-07-09 | 2007-05-09 | Akzo Nobel N.V. | Composition comprising choline hydroxide and process for preparing the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1000902A (fr) * | 1949-11-29 | 1952-02-18 | Chimiotherapie Lab Franc | Procédé amélioré pour la préparation des solutions aqueuses de sels d'acide paraaminosalicylique |
| DE1104118B (de) * | 1959-05-15 | 1961-04-06 | Benckiser Gmbh Joh A | Verfahren zur Erhoehung der thermischen Stabilitaet von waessrigen, pharmakologisch wirksamen Aminozuckerderivatloesungen |
| US3069321A (en) * | 1960-04-04 | 1962-12-18 | Lab For Pharmaceutical Dev Inc | Choline salicylate composition and methods of use |
| US3549370A (en) * | 1966-11-23 | 1970-12-22 | Hunt Chem Corp Philip A | Quaternary ammonium bisulfites,sulfites or pyrosulfites as developer preservatives |
| DE1956626A1 (de) * | 1969-11-11 | 1971-05-19 | Basf Ag | Verfahren zur Herstellung von Sulfitobetainen |
-
1971
- 1971-07-26 GB GB3494171A patent/GB1397732A/en not_active Expired
-
1972
- 1972-03-24 US US00237927A patent/US3855282A/en not_active Expired - Lifetime
- 1972-04-25 ZA ZA722798A patent/ZA722798B/xx unknown
- 1972-05-09 ES ES402541A patent/ES402541A1/es not_active Expired
- 1972-05-10 DE DE2222902A patent/DE2222902C2/de not_active Expired
- 1972-05-16 AU AU42323/72A patent/AU461584B2/en not_active Expired
- 1972-06-27 CH CH962572A patent/CH590816A5/xx not_active IP Right Cessation
- 1972-06-30 CA CA146,186A patent/CA1009664A/en not_active Expired
- 1972-07-25 NO NO2651/72A patent/NO146137C/no unknown
- 1972-07-25 FR FR7226732A patent/FR2147170B1/fr not_active Expired
- 1972-07-25 DK DK368072A patent/DK145540C/da not_active IP Right Cessation
- 1972-10-11 IL IL40542A patent/IL40542A/xx unknown
- 1972-12-04 IN IN2052/72A patent/IN139346B/en unknown
- 1972-12-28 ES ES410123A patent/ES410123A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0051962A3 (en) * | 1980-11-05 | 1982-09-29 | Sumitomo Chemical Company, Limited | Pharmaceutical composition comprising 4-carbamoyl-imidazolium-5-oleate |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4232372A (en) | 1973-11-22 |
| NO146137B (no) | 1982-04-26 |
| ES402541A1 (es) | 1975-04-01 |
| ES410123A1 (es) | 1976-05-16 |
| DK145540B (da) | 1982-12-06 |
| IL40542A (en) | 1979-07-25 |
| AU461584B2 (en) | 1975-05-29 |
| IN139346B (https=) | 1976-06-12 |
| CH590816A5 (https=) | 1977-08-31 |
| CA1009664A (en) | 1977-05-03 |
| NO146137C (no) | 1982-08-04 |
| DE2222902A1 (de) | 1973-02-08 |
| US3855282A (en) | 1974-12-17 |
| IL40542A0 (en) | 1972-12-29 |
| FR2147170B1 (https=) | 1976-04-16 |
| DE2222902C2 (de) | 1985-06-13 |
| FR2147170A1 (https=) | 1973-03-09 |
| ZA722798B (en) | 1973-01-31 |
| DK145540C (da) | 1983-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |