GB1396302A - Amino-pyrazolopyrimidines and processes for their production - Google Patents

Amino-pyrazolopyrimidines and processes for their production

Info

Publication number
GB1396302A
GB1396302A GB478872*[A GB478872A GB1396302A GB 1396302 A GB1396302 A GB 1396302A GB 478872 A GB478872 A GB 478872A GB 1396302 A GB1396302 A GB 1396302A
Authority
GB
United Kingdom
Prior art keywords
alkyl
hydroxy
compounds
diphenylether
dichloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB478872*[A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AR241693A priority Critical patent/AR205429A1/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Priority to GB478872*[A priority patent/GB1396302A/en
Priority to ES402181A priority patent/ES402181A1/en
Priority to NO01324/72A priority patent/NO129576B/no
Priority to DE19722218717 priority patent/DE2218717A1/en
Priority to IL39247A priority patent/IL39247A/en
Priority to FI1086/72A priority patent/FI54122C/en
Priority to SE7205085A priority patent/SE395275B/en
Priority to IE523/72A priority patent/IE36312B1/en
Priority to PL1972154974A priority patent/PL82369B1/en
Priority to CS278472A priority patent/CS177825B2/cs
Priority to PL1972175239A priority patent/PL84544B1/en
Priority to CH1566374A priority patent/CH572932A5/en
Priority to CH610372A priority patent/CH568320A5/xx
Priority to DK207672AA priority patent/DK138896B/en
Priority to FR7214835A priority patent/FR2134540B1/fr
Priority to CA140,603A priority patent/CA995668A/en
Priority to AT368072A priority patent/AT314527B/en
Priority to BE782658A priority patent/BE782658A/en
Priority to DD162588A priority patent/DD98288A5/xx
Priority to NL7205668A priority patent/NL7205668A/xx
Priority to SU1779675A priority patent/SU493069A3/en
Priority to AU41539/72A priority patent/AU471025B2/en
Priority to AT470373A priority patent/AT320629B/en
Priority to HUCI1229A priority patent/HU168494B/hu
Priority to AR24750773A priority patent/AR205518A1/en
Priority to SU1966875A priority patent/SU493970A3/en
Priority to US05/485,472 priority patent/US3948913A/en
Publication of GB1396302A publication Critical patent/GB1396302A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Control Of Steam Boilers And Waste-Gas Boilers (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1396302 Growth-promoting &c compositions CIBA-GEIGY AG 26 April 1972 [27 April 1971 2 Feb 1972 3 March 1972 (2)] 11492/71 4788/72 10021/72 and 10022/72 Heading A5B [Also in Division C2] Novel compounds II in which R 1 is C 1-3 alkyl, R 2 is hydrogen or C 1-3 alkyl and X is chloro or NR 3 R 4 (in which R 3 is hydrogen, C 1-3 alkyl, hydroxy C 1-3 alkyl, C 2-4 alkenyl C 1-3 alkoxy C 1-3 alkyl or hydroxy, and R 4 is R 3 other than hydoxy- or R 3 and R 4 form a C 4-6 polymethylene chain optionally interrupted by oxygen) and the S-N oxides and acid addition salts of compounds in which X is NR 3 R 4 are anti-microbial agents. Compounds II in which X is NR 3 R 4 their S-N- oxides and acid addition salts form with a carrier or diluent a pharmaceutical composition which may be administered orally or parenterally; they may be added to animal feedstuffs to promote growth or used to protect organic material from bacterial or nucrobial attack. The compositions may also include 5, 7-dichloro-2-methyl-8-quinolinol; sulphamerazine or sulphafurazole; chloramphenicol or tetracyline; 3, 4', 5-tribromocalicylanilide; halogenated carbonilides, benzoxazoles or benzoxazolones; polychloro-hydroxy-diphenylmethanes; halogen-dihydoxy-diphenyl sulphines; 4, 4'- dichloro-2-hydroxyl-diphenylether or 2, 4, 4'- trichloro-2-hydroxy-diphenylether; bactericidal quaternary compounds, or dithiocarbonic acid derivatives (tetra methyl thiuran disulphide) carriers having favourable pharmacological properties may be used; sulphur as a powder base or zinc stearate as an ointment base.
GB478872*[A 1971-04-27 1972-02-02 Amino-pyrazolopyrimidines and processes for their production Expired GB1396302A (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
AR241693A AR205429A1 (en) 1971-04-27 1972-01-01 PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4-AMINO - 3- (5-NITRO- 2 -FURYL) -1-METHYL - 1H - PIRAZOLE- (3,4-OL) -PYRIMIDINE
GB478872*[A GB1396302A (en) 1971-04-27 1972-02-02 Amino-pyrazolopyrimidines and processes for their production
ES402181A ES402181A1 (en) 1971-04-27 1972-04-07 Procedure for the obtaining of derivatives of 5-nitrofurilo. (Machine-translation by Google Translate, not legally binding)
NO01324/72A NO129576B (en) 1971-04-27 1972-04-17
DE19722218717 DE2218717A1 (en) 1971-04-27 1972-04-18 New aminopyrazole pyrimidines
IL39247A IL39247A (en) 1971-04-27 1972-04-18 4-amino-1-alkyl-3-(5-nitro-2-furyl)-1h-pyrazolo(3,4-d)pyrimidines,their production and antimicrobial compositions containing them
FI1086/72A FI54122C (en) 1971-04-27 1972-04-18 FREQUENCY REFRIGERATION OF ANTIMICROBISC VERKSAMMA 3- (5-NITRO-FURYL) -PYRAZOLO (3,4-D) PYRIMIDINER
SE7205085A SE395275B (en) 1971-04-27 1972-04-19 ANALOGICAL PROCEDURE FOR THE PREPARATION OF AMINOPYRAZOLO / 3,4-D / PYRIMIDINES
IE523/72A IE36312B1 (en) 1971-04-27 1972-04-20 Aminopyrazolopyrimidines and processes for their production
CH610372A CH568320A5 (en) 1971-04-27 1972-04-25
CS278472A CS177825B2 (en) 1971-04-27 1972-04-25
PL1972175239A PL84544B1 (en) 1971-04-27 1972-04-25 Amino-pyrazolopyrimidines and processes for their production[gb1396302a]
CH1566374A CH572932A5 (en) 1972-02-02 1972-04-25 Substd 5-nitrofuryl derivs of aminopyrazolepyrimidines - from substd nitrofurylpyrazole and amine, - broad spectrum antimicrobials
PL1972154974A PL82369B1 (en) 1971-04-27 1972-04-25 Amino-pyrazolopyrimidines and processes for their production[gb1396302a]
NL7205668A NL7205668A (en) 1971-04-27 1972-04-26
SU1779675A SU493069A3 (en) 1971-04-27 1972-04-26 Method for preparing aminopyrazolpyrimidine derivatives
CA140,603A CA995668A (en) 1971-04-27 1972-04-26 Aminopyrazolopyrimidines and processes for their production
AT368072A AT314527B (en) 1971-04-27 1972-04-26 Process for the production of new 5-nitrofuran derivatives and their salts
BE782658A BE782658A (en) 1971-04-27 1972-04-26 NEWS AMINOPYRAZOLPYRIMIDINES
DD162588A DD98288A5 (en) 1971-04-27 1972-04-26
DK207672AA DK138896B (en) 1971-04-27 1972-04-26 Analogous process for the preparation of 5-nitrofuryl derivatives of aminopyrazole (3,4-d) pyrimidines or their 5-N-oxides or acid addition salts.
FR7214835A FR2134540B1 (en) 1971-04-27 1972-04-26
AU41539/72A AU471025B2 (en) 1971-04-27 1972-04-26 A aminopyrazolopyrimidines and processes for their production
AT470373A AT320629B (en) 1971-04-27 1972-04-26 Process for the production of new 5-nitrofuran derivatives and their salts
HUCI1229A HU168494B (en) 1971-04-27 1972-04-27
AR24750773A AR205518A1 (en) 1971-04-27 1973-04-11 PROCEDURE FOR THE ELABORATION OF DERIVATIVES OF 1 - METHYL - 4 - AMINO - 3 - (5 - NITRO - 2 - FURYL) - PIRAZOLE - (3,4-D) - PYRIMIDINE
SU1966875A SU493970A3 (en) 1971-04-27 1973-11-05 Method for preparing aminopyrazolpyrimidine derivatives
US05/485,472 US3948913A (en) 1971-04-27 1974-07-03 New 5-nitrofuryl derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1149271 1971-04-27
GB478872*[A GB1396302A (en) 1971-04-27 1972-02-02 Amino-pyrazolopyrimidines and processes for their production
GB1002172 1972-03-03
GB1002272 1972-03-03

Publications (1)

Publication Number Publication Date
GB1396302A true GB1396302A (en) 1975-06-04

Family

ID=27447397

Family Applications (1)

Application Number Title Priority Date Filing Date
GB478872*[A Expired GB1396302A (en) 1971-04-27 1972-02-02 Amino-pyrazolopyrimidines and processes for their production

Country Status (20)

Country Link
AR (1) AR205429A1 (en)
AT (1) AT314527B (en)
AU (1) AU471025B2 (en)
BE (1) BE782658A (en)
CA (1) CA995668A (en)
CH (1) CH568320A5 (en)
DD (1) DD98288A5 (en)
DE (1) DE2218717A1 (en)
DK (1) DK138896B (en)
FI (1) FI54122C (en)
FR (1) FR2134540B1 (en)
GB (1) GB1396302A (en)
HU (1) HU168494B (en)
IE (1) IE36312B1 (en)
IL (1) IL39247A (en)
NL (1) NL7205668A (en)
NO (1) NO129576B (en)
PL (2) PL82369B1 (en)
SE (1) SE395275B (en)
SU (1) SU493069A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009537580A (en) * 2006-05-23 2009-10-29 ノバルティス アクチエンゲゼルシャフト Pyrazolo [3,4-d] pyrimidine derivatives useful for treating respiratory disorders

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205234A1 (en) * 1974-05-13 1976-04-12 Lilly Co Eli PROCEDURE TO PREPARE 3- (5-NITROIMIDAZOL-2-IL) PYRAZOLO (3,4-D) PYRIMIDINE COMPOUNDS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009537580A (en) * 2006-05-23 2009-10-29 ノバルティス アクチエンゲゼルシャフト Pyrazolo [3,4-d] pyrimidine derivatives useful for treating respiratory disorders

Also Published As

Publication number Publication date
CA995668A (en) 1976-08-24
AT314527B (en) 1974-04-10
AR205429A1 (en) 1976-05-07
IL39247A (en) 1975-07-28
IE36312B1 (en) 1976-10-13
NO129576B (en) 1974-04-29
PL84544B1 (en) 1976-04-30
DK138896B (en) 1978-11-13
AU4153972A (en) 1973-11-01
AU471025B2 (en) 1976-04-08
CH568320A5 (en) 1975-10-31
SE395275B (en) 1977-08-08
FR2134540A1 (en) 1972-12-08
FI54122B (en) 1978-06-30
FR2134540B1 (en) 1975-12-26
SU493069A3 (en) 1975-11-25
DE2218717A1 (en) 1972-11-16
DD98288A5 (en) 1973-06-12
FI54122C (en) 1978-10-10
DK138896C (en) 1979-04-30
IL39247A0 (en) 1972-06-28
BE782658A (en) 1972-10-26
NL7205668A (en) 1972-10-31
IE36312L (en) 1972-10-27
PL82369B1 (en) 1975-10-31
HU168494B (en) 1976-05-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee