GB1395666A - Thiophene derivatives processes for their preparation and compositions incorporating them - Google Patents
Thiophene derivatives processes for their preparation and compositions incorporating themInfo
- Publication number
- GB1395666A GB1395666A GB4609073A GB4609073A GB1395666A GB 1395666 A GB1395666 A GB 1395666A GB 4609073 A GB4609073 A GB 4609073A GB 4609073 A GB4609073 A GB 4609073A GB 1395666 A GB1395666 A GB 1395666A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzoylthiophene
- hydrogen atom
- prepared
- preparation
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 150000003577 thiophenes Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- DWYFUJJWTRPARQ-UHFFFAOYSA-N phenyl(thiophen-2-yl)methanone Chemical class C=1C=CC=CC=1C(=O)C1=CC=CS1 DWYFUJJWTRPARQ-UHFFFAOYSA-N 0.000 abstract 3
- 101100188552 Arabidopsis thaliana OCT3 gene Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- -1 methoxy, methyl Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7235297A FR2201883B1 (en:Method) | 1972-10-05 | 1972-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1395666A true GB1395666A (en) | 1975-05-29 |
Family
ID=9105227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4609073A Expired GB1395666A (en) | 1972-10-05 | 1973-10-03 | Thiophene derivatives processes for their preparation and compositions incorporating them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3903114A (en:Method) |
| JP (1) | JPS5636193B2 (en:Method) |
| BE (1) | BE805682A (en:Method) |
| CA (1) | CA975001A (en:Method) |
| CH (1) | CH583223A5 (en:Method) |
| DE (1) | DE2350148A1 (en:Method) |
| FR (1) | FR2201883B1 (en:Method) |
| GB (1) | GB1395666A (en:Method) |
| IE (1) | IE38821B1 (en:Method) |
| NL (1) | NL7313641A (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014440A1 (en) * | 1979-02-02 | 1980-08-20 | Sagami Chemical Research Center | Ketal derivatives and the use thereof as intermediate products |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087542A (en) * | 1975-07-09 | 1978-05-02 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids |
| US4181727A (en) * | 1975-07-09 | 1980-01-01 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids |
| US4296122A (en) * | 1975-07-09 | 1981-10-20 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids |
| JPS5823873B2 (ja) * | 1979-02-02 | 1983-05-18 | 財団法人相模中央化学研究所 | 置換フェニル酢酸誘導体の製造方法 |
| ES479300A1 (es) * | 1979-04-04 | 1979-07-01 | Cusi Lab | Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol. |
| NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
| FR2598412B1 (fr) * | 1986-03-12 | 1988-10-21 | Sanofi Sa | Nouveaux derives de diarylcetones et leurs procedes de preparation et les compositions pharmaceutiques les contenant |
| US5663199A (en) * | 1994-11-30 | 1997-09-02 | Uniroyal Chemical Ltd./Ltee | Anti-viral aromatic O-alkylated oximes, ethers and thioethers |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1180268A (en) * | 1967-09-26 | 1970-02-04 | Ici Ltd | Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives |
| US3655693A (en) * | 1969-06-25 | 1972-04-11 | Merck & Co Inc | Anti-inflammatory salicyclic acid derivatives |
-
1972
- 1972-10-05 FR FR7235297A patent/FR2201883B1/fr not_active Expired
-
1973
- 1973-10-01 US US402030A patent/US3903114A/en not_active Expired - Lifetime
- 1973-10-03 GB GB4609073A patent/GB1395666A/en not_active Expired
- 1973-10-03 JP JP11062373A patent/JPS5636193B2/ja not_active Expired
- 1973-10-03 CA CA182,535A patent/CA975001A/en not_active Expired
- 1973-10-03 IE IE1766/73A patent/IE38821B1/xx unknown
- 1973-10-04 CH CH1418473A patent/CH583223A5/xx not_active IP Right Cessation
- 1973-10-04 BE BE136363A patent/BE805682A/xx not_active IP Right Cessation
- 1973-10-04 NL NL7313641A patent/NL7313641A/xx not_active Application Discontinuation
- 1973-10-05 DE DE19732350148 patent/DE2350148A1/de not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0014440A1 (en) * | 1979-02-02 | 1980-08-20 | Sagami Chemical Research Center | Ketal derivatives and the use thereof as intermediate products |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2350148A1 (de) | 1974-04-18 |
| CH583223A5 (en:Method) | 1976-12-31 |
| CA975001A (en) | 1975-09-23 |
| JPS5636193B2 (en:Method) | 1981-08-22 |
| JPS4970959A (en:Method) | 1974-07-09 |
| FR2201883A1 (en:Method) | 1974-05-03 |
| IE38821B1 (en) | 1978-06-07 |
| IE38821L (en) | 1974-04-05 |
| FR2201883B1 (en:Method) | 1975-10-31 |
| NL7313641A (en:Method) | 1974-04-09 |
| US3903114A (en) | 1975-09-02 |
| BE805682A (fr) | 1974-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |