GB1395253A - In vitro method for determining active substance in a body fluid - Google Patents
In vitro method for determining active substance in a body fluidInfo
- Publication number
- GB1395253A GB1395253A GB2886272A GB2886272A GB1395253A GB 1395253 A GB1395253 A GB 1395253A GB 2886272 A GB2886272 A GB 2886272A GB 2886272 A GB2886272 A GB 2886272A GB 1395253 A GB1395253 A GB 1395253A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substance
- thyroxine
- body fluid
- bound
- labelled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000001124 body fluid Anatomy 0.000 title abstract 5
- 239000010839 body fluid Substances 0.000 title abstract 5
- 239000013543 active substance Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000000338 in vitro Methods 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 9
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 abstract 5
- 229940034208 thyroxine Drugs 0.000 abstract 5
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 abstract 5
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 3
- FTOAOBMCPZCFFF-UHFFFAOYSA-N 5,5-diethylbarbituric acid Chemical compound CCC1(CC)C(=O)NC(=O)NC1=O FTOAOBMCPZCFFF-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- 102000009843 Thyroglobulin Human genes 0.000 abstract 1
- 108010034949 Thyroglobulin Proteins 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 229960002319 barbital Drugs 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 239000003014 ion exchange membrane Substances 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 229960002175 thyroglobulin Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00161882A US3799740A (en) | 1971-07-12 | 1971-07-12 | Clinical competitive-binding test methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1395253A true GB1395253A (en) | 1975-05-21 |
Family
ID=22583178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2886272A Expired GB1395253A (en) | 1971-07-12 | 1972-06-20 | In vitro method for determining active substance in a body fluid |
Country Status (17)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3941564A (en) * | 1973-09-13 | 1976-03-02 | Miles Laboratories, Inc. | Method for assessing thyroid function |
| US3850577A (en) * | 1973-10-31 | 1974-11-26 | Abbott Lab | Rapid extraction method for serum thyroxine |
| US4005187A (en) * | 1974-06-03 | 1977-01-25 | Data Diagnostic Corporation | Diagnostic test method |
| US4064227A (en) * | 1975-03-17 | 1977-12-20 | Mallinckrodt, Inc. | Radioimmunoassay method for the determination of cardiotonic glycosides |
| US4034073A (en) * | 1975-03-28 | 1977-07-05 | Corning Glass Works | Composite for biased solid phase radioimmunoassay of triiodothyronine and thyroxine |
| US4052504A (en) * | 1976-06-30 | 1977-10-04 | Corning Glass Works | Assay for thyroxine binding globulin |
| NL7713952A (nl) * | 1977-12-16 | 1979-06-19 | Philips Nv | Radio-immunologische methode voor het bepalen van de schildklierfunktie door een in vitro onderzoek in bloedserum. |
| USRE34394E (en) * | 1978-01-23 | 1993-09-28 | Baxter Diagnostics Inc. | Method and composition for double receptor, specific binding assays |
| US4292296A (en) * | 1978-09-12 | 1981-09-29 | Baxter Travenol Laboratories, Inc. | Diagnostic method |
| US4393040A (en) * | 1981-03-24 | 1983-07-12 | Lopapa Institute, Inc. | In-vitro diagnostic method for detection of acetylsalicylic acid ingestion |
| US7708699B2 (en) * | 2005-11-18 | 2010-05-04 | Daag International, Inc. | Reflexometry and hormone function |
| CN111295094A (zh) | 2017-10-09 | 2020-06-16 | 泰尔茂比司特生物技术有限公司 | 冻干容器及使用冻干容器的方法 |
| WO2020185909A2 (en) | 2019-03-14 | 2020-09-17 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5249757A (en) * | 1975-10-20 | 1977-04-21 | Fujitsu Ltd | Burst carrier wave detection circuit |
-
1971
- 1971-07-12 US US00161882A patent/US3799740A/en not_active Expired - Lifetime
-
1972
- 1972-06-20 GB GB2886272A patent/GB1395253A/en not_active Expired
- 1972-06-21 AU AU43689/72A patent/AU457051B2/en not_active Expired
- 1972-06-22 IL IL39739A patent/IL39739A/xx unknown
- 1972-06-26 BE BE785417A patent/BE785417A/xx unknown
- 1972-06-26 FR FR7223054A patent/FR2142544A5/fr not_active Expired
- 1972-06-29 NL NL7209081A patent/NL7209081A/xx not_active Application Discontinuation
- 1972-07-06 CA CA146,537A patent/CA1015251A/en not_active Expired
- 1972-07-08 IT IT51434/72A patent/IT1003512B/it active
- 1972-07-10 DE DE2234382A patent/DE2234382C3/de not_active Expired
- 1972-07-10 PL PL1972156623A patent/PL82595B1/pl unknown
- 1972-07-11 SE SE7209146A patent/SE406647B/xx unknown
- 1972-07-11 JP JP47069487A patent/JPS5249757B1/ja active Pending
- 1972-07-12 DD DD164372A patent/DD97752A5/xx unknown
- 1972-07-12 RO RO71582A patent/RO61156A/ro unknown
- 1972-07-12 ES ES404772A patent/ES404772A1/es not_active Expired
-
1973
- 1973-03-29 SU SU7301902369A patent/SU576976A3/ru active
-
1975
- 1975-04-15 AU AU80140/75A patent/AU8014075A/en not_active Expired
-
1976
- 1976-03-11 JP JP51026611A patent/JPS51128413A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PL82595B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-31 |
| AU8014075A (en) | 1975-07-17 |
| JPS51128413A (en) | 1976-11-09 |
| DE2234382C3 (de) | 1979-02-15 |
| ES404772A1 (es) | 1975-11-16 |
| AU4368972A (en) | 1974-02-14 |
| FR2142544A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-01-26 |
| IT1003512B (it) | 1976-06-10 |
| DE2234382A1 (de) | 1973-01-25 |
| IL39739A0 (en) | 1972-08-30 |
| SE406647B (sv) | 1979-02-19 |
| NL7209081A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-01-16 |
| BE785417A (fr) | 1972-12-27 |
| JPS5249757B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-12-19 |
| DD97752A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-05-05 |
| RO61156A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-15 |
| DE2234382B2 (de) | 1975-10-30 |
| AU457051B2 (en) | 1975-01-16 |
| IL39739A (en) | 1975-03-13 |
| SU576976A3 (ru) | 1977-10-15 |
| US3799740A (en) | 1974-03-26 |
| CA1015251A (en) | 1977-08-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4243749A (en) | Immunoassay employing an enzyme label | |
| EP0149631B1 (en) | Free ligand assay | |
| EP0106370A3 (en) | Specific binding assays utilizing analyte-cytolysin conjugates | |
| GB1395253A (en) | In vitro method for determining active substance in a body fluid | |
| GB8800702D0 (en) | Test method & reagent kit therefor | |
| ES8101647A1 (es) | Un metodo de determinacion de ligandos en muestras de ensayo | |
| EP0399184A3 (en) | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | |
| IE42613L (en) | Immunoassay | |
| GB1524372A (en) | Radioassay of oestrogens | |
| KR830010384A (ko) | 항원 항체 반응의 측정 방법 및 그 시약 | |
| GB1528071A (en) | Radioimmunoassay | |
| EP0122695A1 (en) | Immunoassay for antigens employing supported binder | |
| GB1499958A (en) | Radioimmunoassay methods for the determination of thyroxine | |
| EP0089806A1 (en) | Assay for the free portion of substances in biological fluids | |
| US4157895A (en) | RIA reagents and processes | |
| GB1508104A (en) | Method for quantitative determination of an antigenic substance and a diagnostic kit therefor | |
| US4418151A (en) | Assay process with non-boiling denaturation | |
| US4645747A (en) | Specific binding assay technique | |
| DE3482338D1 (de) | Bestimmung der ungesaettigten eisenbindungskapazitaet. | |
| US4052504A (en) | Assay for thyroxine binding globulin | |
| ES435761A1 (es) | Procedimiento de analisis radioisotopico competitivo para medir la concentracion de folato en el suero. | |
| GB1503409A (en) | Analytical test device for carrying out a method of detecting or determining antibodies in body fluids by means of known antigens or detecting or determining antigens by means of known antibodies | |
| ES422273A1 (es) | Procedimiento mejorado paa la determinacion de tiroxina de suero en sanguineo. | |
| DK199783A (da) | Immunoglobulin-halvmolekyler og fremgangsmaade til fremstilling af hybrid-antistoffer | |
| Wood et al. | A rapid and specific method for separation of bound and free antigen in radioimmunoassay systems |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |