GB1391271A - Preparation of antibiotic compounds - Google Patents
Preparation of antibiotic compoundsInfo
- Publication number
- GB1391271A GB1391271A GB1244471A GB1244471A GB1391271A GB 1391271 A GB1391271 A GB 1391271A GB 1244471 A GB1244471 A GB 1244471A GB 1244471 A GB1244471 A GB 1244471A GB 1391271 A GB1391271 A GB 1391271A
- Authority
- GB
- United Kingdom
- Prior art keywords
- forming
- carried out
- preparation
- reaction
- forming compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000003115 biocidal effect Effects 0.000 title 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 4
- 150000008064 anhydrides Chemical class 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 150000003949 imides Chemical class 0.000 abstract 3
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 3
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- JLTDJTHDQAWBAV-UHFFFAOYSA-N N,N-dimethylaniline Chemical compound CN(C)C1=CC=CC=C1 JLTDJTHDQAWBAV-UHFFFAOYSA-N 0.000 abstract 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- IKWLIQXIPRUIDU-ZCFIWIBFSA-N (6r)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound OC(=O)C1=CCS[C@@H]2CC(=O)N12 IKWLIQXIPRUIDU-ZCFIWIBFSA-N 0.000 abstract 1
- ZEYHEAKUIGZSGI-UHFFFAOYSA-N 4-methoxybenzoic acid Chemical compound COC1=CC=C(C(O)=O)C=C1 ZEYHEAKUIGZSGI-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- VGCXGMAHQTYDJK-UHFFFAOYSA-N Chloroacetyl chloride Chemical compound ClCC(Cl)=O VGCXGMAHQTYDJK-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- -1 alkane diol Chemical class 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- ILUJQPXNXACGAN-UHFFFAOYSA-N ortho-methoxybenzoic acid Natural products COC1=CC=CC=C1C(O)=O ILUJQPXNXACGAN-UHFFFAOYSA-N 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1244471A GB1391271A (en) | 1971-04-30 | 1971-04-30 | Preparation of antibiotic compounds |
| AT375572A AT326815B (de) | 1971-04-30 | 1972-04-28 | Verfahren zur herstellung einer 7-aminocephalosporin-4-carbonsaure |
| CH635472A CH576981A5 (enrdf_load_stackoverflow) | 1971-04-30 | 1972-04-28 | |
| JP4323772A JPS558987B1 (enrdf_load_stackoverflow) | 1971-04-30 | 1972-04-28 | |
| NL7205789A NL7205789A (enrdf_load_stackoverflow) | 1971-04-30 | 1972-04-28 | |
| FR7215261A FR2136786A5 (enrdf_load_stackoverflow) | 1971-04-30 | 1972-04-28 | |
| BE782807A BE782807A (fr) | 1971-04-30 | 1972-04-28 | Procede de preparation de composes antibiotiques |
| DE19722221070 DE2221070C2 (de) | 1971-04-30 | 1972-04-28 | Verfahren zur Herstellung von 7-Amino-cheph-3-em-4-carbonsäure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1244471A GB1391271A (en) | 1971-04-30 | 1971-04-30 | Preparation of antibiotic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1391271A true GB1391271A (en) | 1975-04-16 |
Family
ID=10004718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1244471A Expired GB1391271A (en) | 1971-04-30 | 1971-04-30 | Preparation of antibiotic compounds |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS558987B1 (enrdf_load_stackoverflow) |
| AT (1) | AT326815B (enrdf_load_stackoverflow) |
| BE (1) | BE782807A (enrdf_load_stackoverflow) |
| CH (1) | CH576981A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2221070C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2136786A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1391271A (enrdf_load_stackoverflow) |
| NL (1) | NL7205789A (enrdf_load_stackoverflow) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR70261B (enrdf_load_stackoverflow) * | 1977-12-12 | 1982-09-02 | Takeda Chemical Industries Ltd | |
| JPH03100840U (enrdf_load_stackoverflow) * | 1990-02-02 | 1991-10-22 | ||
| US5391226A (en) * | 1992-04-23 | 1995-02-21 | Tiremix Corporation | Rubber-crumb-reinforced cement concrete |
| JPH0684451U (ja) * | 1993-05-11 | 1994-12-02 | 正宣 賀川 | 工事黒板付カメラ |
| JPH06324398A (ja) * | 1993-05-11 | 1994-11-25 | Ryoichi Sato | ボード写し込み装置 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1241655A (en) * | 1967-08-21 | 1971-08-04 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin compounds |
-
1971
- 1971-04-30 GB GB1244471A patent/GB1391271A/en not_active Expired
-
1972
- 1972-04-28 DE DE19722221070 patent/DE2221070C2/de not_active Expired
- 1972-04-28 NL NL7205789A patent/NL7205789A/xx not_active Application Discontinuation
- 1972-04-28 AT AT375572A patent/AT326815B/de not_active IP Right Cessation
- 1972-04-28 FR FR7215261A patent/FR2136786A5/fr not_active Expired
- 1972-04-28 BE BE782807A patent/BE782807A/xx not_active IP Right Cessation
- 1972-04-28 JP JP4323772A patent/JPS558987B1/ja active Pending
- 1972-04-28 CH CH635472A patent/CH576981A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7205789A (enrdf_load_stackoverflow) | 1972-11-01 |
| AT326815B (de) | 1975-12-29 |
| JPS558987B1 (enrdf_load_stackoverflow) | 1980-03-07 |
| FR2136786A5 (enrdf_load_stackoverflow) | 1972-12-22 |
| DE2221070C2 (de) | 1982-04-15 |
| DE2221070A1 (de) | 1972-11-23 |
| CH576981A5 (enrdf_load_stackoverflow) | 1976-06-30 |
| ATA375572A (de) | 1975-03-15 |
| BE782807A (fr) | 1972-10-30 |
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| US3466275A (en) | Modified penicillins and their preparation via penicillin sulfoxides | |
| IL42087A (en) | The preparation of 7-aminocephalosporanic acid derivative | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |