GB1387376A - Cycloalkano-quinolone-carboxylic acid esters - Google Patents
Cycloalkano-quinolone-carboxylic acid estersInfo
- Publication number
- GB1387376A GB1387376A GB698773A GB698773A GB1387376A GB 1387376 A GB1387376 A GB 1387376A GB 698773 A GB698773 A GB 698773A GB 698773 A GB698773 A GB 698773A GB 1387376 A GB1387376 A GB 1387376A
- Authority
- GB
- United Kingdom
- Prior art keywords
- denotes
- carbon atoms
- carboxylic acid
- acid esters
- cycloalkano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel cycloalkanoquinolonecarboxylic acid esters of the accompanying formula I, in which R denotes an alkyl group having 1 to 5, preferably 1 to 3, carbon atoms; X denotes an alkyl group having 1 to 5 carbon atoms, which is optionally substituted by halogen, preferably chlorine, or a hydroxy, alkoxy, acyloxy or alkylmercapto group, or denotes an alkenyl group having up to 5 carbon atoms; and n denotes one of the numbers 3 to 5 are prepared; the process is based on the esterification of the corresponding free acid with the agent donating the radical R. The free carboxylic acid can for its part be obtained by cyclisation of the corresponding compounds which carry a corresponding omega -haloalkyl or omega -alkenyl group in the 8-position. The compounds of the formula I can be used for the preparation of medicaments having antimicrobial action. <IMAGE>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2207856A DE2207856A1 (en) | 1972-02-19 | 1972-02-19 | CYCLOALKANOCHINOLONE CARBONIC ACID ESTERS AND PROCESS FOR THEIR PRODUCTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1387376A true GB1387376A (en) | 1975-03-19 |
Family
ID=5836457
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3879874A Expired GB1394050A (en) | 1972-02-19 | 1973-02-13 | Pharmaceutical compositions containing cycloalkanoquinolone- carboxylic acid esters |
| GB698773A Expired GB1387376A (en) | 1972-02-19 | 1973-02-13 | Cycloalkano-quinolone-carboxylic acid esters |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3879874A Expired GB1394050A (en) | 1972-02-19 | 1973-02-13 | Pharmaceutical compositions containing cycloalkanoquinolone- carboxylic acid esters |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS512472B2 (en) |
| AR (1) | AR195319A1 (en) |
| AT (1) | AT327196B (en) |
| AU (1) | AU451376B2 (en) |
| CA (1) | CA981683A (en) |
| CH (2) | CH605781A5 (en) |
| DD (1) | DD106038A5 (en) |
| DE (1) | DE2207856A1 (en) |
| ES (1) | ES411619A1 (en) |
| FR (1) | FR2181740B1 (en) |
| GB (2) | GB1394050A (en) |
| NL (1) | NL156690B (en) |
| SE (1) | SE381044B (en) |
| ZA (1) | ZA731067B (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2043817C3 (en) * | 1970-09-04 | 1981-09-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | 1,4-Dihydro-3-carboxy-cyclopentano- (h) -quinolone- (4) derivatives, processes for their preparation and their use for combating antibacterial diseases |
| DE1770951A1 (en) * | 1968-07-23 | 1972-04-06 | Boehringer Mannheim Gmbh | Cyclopentanoquinolone derivatives and processes for their preparation |
| CA944354A (en) * | 1968-07-23 | 1974-03-26 | Boehringer Mannheim G.M.B.H. | Cycloalkano-quinolone derivatives |
| DE1912944A1 (en) * | 1969-03-14 | 1970-10-01 | Boehringer Mannheim Gmbh | Cycloalkanoquinolone derivatives and processes for their preparation |
| DE2103805C3 (en) * | 1970-01-28 | 1980-03-20 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | Process for the preparation of N-substituted 6,7-methylenedioxy-4-quinolones |
-
1972
- 1972-02-19 DE DE2207856A patent/DE2207856A1/en active Pending
-
1973
- 1973-02-12 DD DD168815A patent/DD106038A5/en unknown
- 1973-02-13 GB GB3879874A patent/GB1394050A/en not_active Expired
- 1973-02-13 SE SE7301998A patent/SE381044B/en unknown
- 1973-02-13 NL NL7301994.A patent/NL156690B/en unknown
- 1973-02-13 AU AU52120/73A patent/AU451376B2/en not_active Expired
- 1973-02-13 GB GB698773A patent/GB1387376A/en not_active Expired
- 1973-02-14 CA CA163,692A patent/CA981683A/en not_active Expired
- 1973-02-14 ES ES411619A patent/ES411619A1/en not_active Expired
- 1973-02-15 AT AT135673A patent/AT327196B/en not_active IP Right Cessation
- 1973-02-15 ZA ZA731067A patent/ZA731067B/en unknown
- 1973-02-16 CH CH225373A patent/CH605781A5/xx not_active IP Right Cessation
- 1973-02-16 FR FR7305514A patent/FR2181740B1/fr not_active Expired
- 1973-02-18 AR AR246574A patent/AR195319A1/en active
- 1973-02-19 JP JP48020095A patent/JPS512472B2/ja not_active Expired
-
1977
- 1977-11-18 CH CH1413377A patent/CH616155A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2181740A1 (en) | 1973-12-07 |
| NL7301994A (en) | 1973-08-21 |
| AT327196B (en) | 1976-01-26 |
| AU451376B2 (en) | 1974-08-08 |
| CH616155A5 (en) | 1980-03-14 |
| ATA135673A (en) | 1975-04-15 |
| AR195319A1 (en) | 1973-09-28 |
| ZA731067B (en) | 1973-12-19 |
| AU5212073A (en) | 1974-08-08 |
| DD106038A5 (en) | 1974-05-20 |
| JPS512472B2 (en) | 1976-01-26 |
| JPS4886872A (en) | 1973-11-15 |
| ES411619A1 (en) | 1976-01-01 |
| GB1394050A (en) | 1975-05-14 |
| CA981683A (en) | 1976-01-13 |
| DE2207856A1 (en) | 1973-08-23 |
| NL156690B (en) | 1978-05-16 |
| SE381044B (en) | 1975-11-24 |
| CH605781A5 (en) | 1978-10-13 |
| FR2181740B1 (en) | 1976-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |