GB1386130A - 1,2-biguanides - Google Patents
1,2-biguanidesInfo
- Publication number
- GB1386130A GB1386130A GB1416272A GB1416272A GB1386130A GB 1386130 A GB1386130 A GB 1386130A GB 1416272 A GB1416272 A GB 1416272A GB 1416272 A GB1416272 A GB 1416272A GB 1386130 A GB1386130 A GB 1386130A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- salt
- reaction
- acid addition
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940123208 Biguanide Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 abstract 2
- LIMQQADUEULBSO-UHFFFAOYSA-N butyl isothiocyanate Chemical compound CCCCN=C=S LIMQQADUEULBSO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001718 carbodiimides Chemical class 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 2
- UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 abstract 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 abstract 2
- 150000003512 tertiary amines Chemical class 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- UHEZLJYVTUWEOM-UHFFFAOYSA-N 1-butyl-3-(diaminomethylidene)thiourea;carbonic acid Chemical compound OC(O)=O.CCCCNC(=S)NC(N)=N UHEZLJYVTUWEOM-UHFFFAOYSA-N 0.000 abstract 1
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 abstract 1
- DRSHXJFUUPIBHX-UHFFFAOYSA-N COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 Chemical compound COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 DRSHXJFUUPIBHX-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 150000004283 biguanides Chemical class 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- OKGXJRGLYVRVNE-UHFFFAOYSA-N diaminomethylidenethiourea Chemical compound NC(N)=NC(N)=S OKGXJRGLYVRVNE-UHFFFAOYSA-N 0.000 abstract 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 229960004198 guanidine Drugs 0.000 abstract 1
- 229960000789 guanidine hydrochloride Drugs 0.000 abstract 1
- 150000002357 guanidines Chemical class 0.000 abstract 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910001385 heavy metal Inorganic materials 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229940101209 mercuric oxide Drugs 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910044991 metal oxide Inorganic materials 0.000 abstract 1
- 150000004706 metal oxides Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229910001961 silver nitrate Inorganic materials 0.000 abstract 1
- -1 silver nitrate and Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/02—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design characterised by the drive of the dental tools
- A61C1/05—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design characterised by the drive of the dental tools with turbine drive
- A61C1/057—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design characterised by the drive of the dental tools with turbine drive with means for preventing suction effect in turbine after deactivation of the drive air
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712117015 DE2117015A1 (de) | 1971-04-02 | 1971-04-02 | 1,2-Biguanide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1386130A true GB1386130A (en) | 1975-03-05 |
Family
ID=5804148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1416272A Expired GB1386130A (en) | 1971-04-02 | 1972-03-27 | 1,2-biguanides |
Country Status (19)
| Country | Link |
|---|---|
| AR (3) | AR194360A1 (cg-RX-API-DMAC10.html) |
| AT (4) | AT317239B (cg-RX-API-DMAC10.html) |
| AU (1) | AU468307B2 (cg-RX-API-DMAC10.html) |
| BE (1) | BE781590A (cg-RX-API-DMAC10.html) |
| CA (1) | CA988084A (cg-RX-API-DMAC10.html) |
| CH (1) | CH579534A5 (cg-RX-API-DMAC10.html) |
| CS (3) | CS161935B2 (cg-RX-API-DMAC10.html) |
| DD (1) | DD95228A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2117015A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK129651B (cg-RX-API-DMAC10.html) |
| ES (1) | ES401124A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2132396B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1386130A (cg-RX-API-DMAC10.html) |
| HU (1) | HU162902B (cg-RX-API-DMAC10.html) |
| NL (1) | NL7204493A (cg-RX-API-DMAC10.html) |
| NO (1) | NO135418C (cg-RX-API-DMAC10.html) |
| SE (1) | SE377332B (cg-RX-API-DMAC10.html) |
| SU (4) | SU535903A3 (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA722183B (cg-RX-API-DMAC10.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008007314A1 (de) | 2008-02-02 | 2009-08-06 | Merck Patent Gmbh | Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR940304A (fr) * | 1946-01-07 | 1948-12-09 | Ici Ltd | Procédé de fabrication de dérivés de biguanides |
-
1971
- 1971-04-02 DE DE19712117015 patent/DE2117015A1/de not_active Withdrawn
-
1972
- 1972-03-15 CS CS1724A patent/CS161935B2/cs unknown
- 1972-03-15 CS CS6963*A patent/CS161936B2/cs unknown
- 1972-03-15 CS CS6964*A patent/CS161937B2/cs unknown
- 1972-03-22 DK DK134572AA patent/DK129651B/da unknown
- 1972-03-23 ES ES401124A patent/ES401124A1/es not_active Expired
- 1972-03-27 GB GB1416272A patent/GB1386130A/en not_active Expired
- 1972-03-27 CH CH454672A patent/CH579534A5/xx not_active IP Right Cessation
- 1972-03-29 AR AR241248A patent/AR194360A1/es active
- 1972-03-29 NO NO1084/72A patent/NO135418C/no unknown
- 1972-03-29 SE SE7204127A patent/SE377332B/xx unknown
- 1972-03-30 AT AT00784/73A patent/AT317239B/de not_active IP Right Cessation
- 1972-03-30 AT AT279272A patent/AT313301B/de not_active IP Right Cessation
- 1972-03-30 HU HUSC383A patent/HU162902B/hu unknown
- 1972-03-30 DD DD161938A patent/DD95228A5/xx unknown
- 1972-03-30 ZA ZA722183A patent/ZA722183B/xx unknown
- 1972-03-30 AT AT00786/73A patent/AT321318B/de not_active IP Right Cessation
- 1972-03-30 AT AT00785/73A patent/AT317240B/de not_active IP Right Cessation
- 1972-03-30 AU AU40661/72A patent/AU468307B2/en not_active Expired
- 1972-03-31 SU SU1767915A patent/SU535903A3/ru active
- 1972-03-31 SU SU1907665A patent/SU465784A3/ru active
- 1972-03-31 BE BE781590A patent/BE781590A/xx unknown
- 1972-03-31 SU SU1907668A patent/SU493959A3/ru active
- 1972-03-31 SU SU1907667A patent/SU472501A3/ru active
- 1972-04-04 NL NL7204493A patent/NL7204493A/xx not_active Application Discontinuation
- 1972-04-04 FR FR7211727A patent/FR2132396B1/fr not_active Expired
- 1972-04-04 CA CA138,838A patent/CA988084A/en not_active Expired
- 1972-11-13 AR AR245079A patent/AR194285A1/es active
- 1972-11-13 AR AR245080A patent/AR192485A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |