GB1385472A - Antibiotics - Google Patents
AntibioticsInfo
- Publication number
- GB1385472A GB1385472A GB537571A GB537571A GB1385472A GB 1385472 A GB1385472 A GB 1385472A GB 537571 A GB537571 A GB 537571A GB 537571 A GB537571 A GB 537571A GB 1385472 A GB1385472 A GB 1385472A
- Authority
- GB
- United Kingdom
- Prior art keywords
- penicillin
- bromoarylacetamido
- feb
- oxides
- bromination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 229930182555 Penicillin Natural products 0.000 abstract 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 3
- 229940049954 penicillin Drugs 0.000 abstract 3
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- 230000031709 bromination Effects 0.000 abstract 2
- 238000005893 bromination reaction Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- OYCZMXMBFKVLGH-UHFFFAOYSA-N 1,3,5-tribromo-1,2,4-triazole Chemical compound BrC=1N=C(Br)N(Br)N=1 OYCZMXMBFKVLGH-UHFFFAOYSA-N 0.000 abstract 1
- -1 3-methylcephem compound Chemical class 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- FNXLCIKXHOPCKH-UHFFFAOYSA-N bromamine Chemical compound BrN FNXLCIKXHOPCKH-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 abstract 1
- 229940106164 cephalexin Drugs 0.000 abstract 1
- 150000001782 cephems Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB537571A GB1385472A (en) | 1971-02-24 | 1971-02-24 | Antibiotics |
| JP1815372A JPS5421357B2 (enrdf_load_stackoverflow) | 1971-02-24 | 1972-02-23 | |
| IE22272A IE36117B1 (en) | 1971-02-24 | 1972-02-23 | Improvements in or relating to antibiotics |
| CH261372A CH571526A5 (enrdf_load_stackoverflow) | 1971-02-24 | 1972-02-23 | |
| FR7206055A FR2126329A1 (en) | 1971-02-24 | 1972-02-23 | Bromination of penicillin (s-oxides) |
| DE19722208582 DE2208582A1 (de) | 1971-02-24 | 1972-02-23 | Penicilhnderivate |
| CA135,345A CA980338A (en) | 1971-02-24 | 1972-02-23 | Bromination of 6-arylacetamidopenicillin 1-oxide |
| BE779702A BE779702A (enrdf_load_stackoverflow) | 1971-02-24 | 1972-02-23 | |
| AT147872A AT322103B (de) | 1971-02-24 | 1972-02-23 | Verfahren zur herstellung von neuen penicillinderivaten |
| NL7202385A NL7202385A (enrdf_load_stackoverflow) | 1971-02-24 | 1972-02-23 | |
| CA157,063A CA982557A (en) | 1971-02-24 | 1972-11-21 | Process for the preparation of 6-2-bromoarylacetamido penicillin 1-oxides |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB537571A GB1385472A (en) | 1971-02-24 | 1971-02-24 | Antibiotics |
| GB5417071 | 1971-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1385472A true GB1385472A (en) | 1975-02-26 |
Family
ID=26239839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB537571A Expired GB1385472A (en) | 1971-02-24 | 1971-02-24 | Antibiotics |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5421357B2 (enrdf_load_stackoverflow) |
| AT (1) | AT322103B (enrdf_load_stackoverflow) |
| BE (1) | BE779702A (enrdf_load_stackoverflow) |
| CA (1) | CA982557A (enrdf_load_stackoverflow) |
| CH (1) | CH571526A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2208582A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1385472A (enrdf_load_stackoverflow) |
| IE (1) | IE36117B1 (enrdf_load_stackoverflow) |
| NL (1) | NL7202385A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3753562A1 (en) | 2017-01-18 | 2020-12-23 | Alpha-1 Biologics LLC | Compositions comprising the tromethamine salt of l-ampicillin. |
-
1971
- 1971-02-24 GB GB537571A patent/GB1385472A/en not_active Expired
-
1972
- 1972-02-23 BE BE779702A patent/BE779702A/xx unknown
- 1972-02-23 AT AT147872A patent/AT322103B/de not_active IP Right Cessation
- 1972-02-23 JP JP1815372A patent/JPS5421357B2/ja not_active Expired
- 1972-02-23 NL NL7202385A patent/NL7202385A/xx unknown
- 1972-02-23 DE DE19722208582 patent/DE2208582A1/de active Pending
- 1972-02-23 IE IE22272A patent/IE36117B1/xx unknown
- 1972-02-23 CH CH261372A patent/CH571526A5/xx not_active IP Right Cessation
- 1972-11-21 CA CA157,063A patent/CA982557A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2208582A1 (de) | 1972-09-21 |
| CH571526A5 (enrdf_load_stackoverflow) | 1976-01-15 |
| CA982557A (en) | 1976-01-27 |
| JPS4844292A (enrdf_load_stackoverflow) | 1973-06-26 |
| AT322103B (de) | 1975-05-12 |
| BE779702A (enrdf_load_stackoverflow) | 1972-08-23 |
| IE36117L (en) | 1972-08-24 |
| IE36117B1 (en) | 1976-08-18 |
| JPS5421357B2 (enrdf_load_stackoverflow) | 1979-07-30 |
| NL7202385A (enrdf_load_stackoverflow) | 1972-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |