GB1382965A - Morpholine derivatives - Google Patents

Morpholine derivatives

Info

Publication number
GB1382965A
GB1382965A GB3391273A GB3391273A GB1382965A GB 1382965 A GB1382965 A GB 1382965A GB 3391273 A GB3391273 A GB 3391273A GB 3391273 A GB3391273 A GB 3391273A GB 1382965 A GB1382965 A GB 1382965A
Authority
GB
United Kingdom
Prior art keywords
radical
hydrogen
carbon atoms
morpholine derivatives
morpholine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3391273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB3391273A priority Critical patent/GB1382965A/en
Publication of GB1382965A publication Critical patent/GB1382965A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1382965 Morpholine derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 18 July 1973 [11 Aug 1972] 33912/73 Divided out of 1382526 Heading C2C [Also in Division A5] The invention comprises novel therapeutic compounds (I) (including salts thereof) wherein R<SP>1</SP> is hydrogen or an acyl radical of up to 4 carbon atoms; R<SP>2</SP> is hydrogen or an alkyl radical of 1 to 6 carbon atoms; R<SP>3</SP> is a halogen atom, an alkyl radical of 1 to 4 carbon atoms, a methoxy radical, a methylthio radical or a trifluoromethyl radical; and R<SP>4</SP> is hydrogen or a trifluormethyl radical. They are made by standard methods, e.g. by hydrolysis or by using compounds corresponding to (I) where the N-atom of the morpholine ring is benzylated.
GB3391273A 1972-08-11 1972-08-11 Morpholine derivatives Expired GB1382965A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3391273A GB1382965A (en) 1972-08-11 1972-08-11 Morpholine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3391273A GB1382965A (en) 1972-08-11 1972-08-11 Morpholine derivatives

Publications (1)

Publication Number Publication Date
GB1382965A true GB1382965A (en) 1975-02-05

Family

ID=10359027

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3391273A Expired GB1382965A (en) 1972-08-11 1972-08-11 Morpholine derivatives

Country Status (1)

Country Link
GB (1) GB1382965A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015052A1 (en) * 1992-01-28 1993-08-05 Smithkline Beecham Plc Compounds as calcium channel antagonists
WO2000071518A2 (en) * 1999-05-25 2000-11-30 Sepracor, Inc. Heterocyclic analgesic compounds and their use
WO2001092226A1 (en) * 2000-05-25 2001-12-06 Sepracor, Inc. Heterocyclic analgesic compounds and method of use thereof
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US7132551B2 (en) 2000-09-11 2006-11-07 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
US7361666B2 (en) 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015052A1 (en) * 1992-01-28 1993-08-05 Smithkline Beecham Plc Compounds as calcium channel antagonists
AU777760B2 (en) * 1999-05-25 2004-10-28 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
WO2000071518A2 (en) * 1999-05-25 2000-11-30 Sepracor, Inc. Heterocyclic analgesic compounds and their use
WO2000071518A3 (en) * 1999-05-25 2001-10-18 Sepracor Inc Heterocyclic analgesic compounds and their use
US7361666B2 (en) 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US7129228B2 (en) 1999-05-25 2006-10-31 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
WO2001092226A1 (en) * 2000-05-25 2001-12-06 Sepracor, Inc. Heterocyclic analgesic compounds and method of use thereof
US6645980B1 (en) 2000-05-25 2003-11-11 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US7132551B2 (en) 2000-09-11 2006-11-07 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
US7517892B2 (en) 2000-09-11 2009-04-14 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof
US7816375B2 (en) 2000-09-11 2010-10-19 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee