FR2234310A1 - Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields - Google Patents

Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields

Info

Publication number
FR2234310A1
FR2234310A1 FR7322696A FR7322696A FR2234310A1 FR 2234310 A1 FR2234310 A1 FR 2234310A1 FR 7322696 A FR7322696 A FR 7322696A FR 7322696 A FR7322696 A FR 7322696A FR 2234310 A1 FR2234310 A1 FR 2234310A1
Authority
FR
France
Prior art keywords
azido
dialkylamino
tris
peptide
high yields
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7322696A
Other languages
French (fr)
Other versions
FR2234310B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CASTRO BERNARD FR
Original Assignee
CASTRO BERNARD FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CASTRO BERNARD FR filed Critical CASTRO BERNARD FR
Priority to FR7322696A priority Critical patent/FR2234310A1/en
Publication of FR2234310A1 publication Critical patent/FR2234310A1/en
Application granted granted Critical
Publication of FR2234310B1 publication Critical patent/FR2234310B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/224—Phosphorus triamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Azido-tris-(dialkylamino) phosphonium salts of formula I (where R1, R2 are 1-5C alkyl; or R1+R2 and the attached N-atom form a 5- or 6-membered heterocyclic gp., contg. 1 or 2 heteroatoms; A is a monovalent anion) are peptide-coupling reagents giving high yields.
FR7322696A 1973-06-21 1973-06-21 Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields Granted FR2234310A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7322696A FR2234310A1 (en) 1973-06-21 1973-06-21 Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7322696A FR2234310A1 (en) 1973-06-21 1973-06-21 Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields

Publications (2)

Publication Number Publication Date
FR2234310A1 true FR2234310A1 (en) 1975-01-17
FR2234310B1 FR2234310B1 (en) 1976-04-30

Family

ID=9121348

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7322696A Granted FR2234310A1 (en) 1973-06-21 1973-06-21 Azido-tris (dialkylamino) phosphonium salts - as peptide-coupling agents giving high yields

Country Status (1)

Country Link
FR (1) FR2234310A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430935A1 (en) * 1978-07-15 1980-02-08 Antibioticos Sa CARBOXYLIC ACID ACTIVATION PROCESS
FR2643374A1 (en) * 1989-02-23 1990-08-24 Centre Nat Rech Scient TRISTETRAMETHYLENE-AMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATES AS PEPTIDE COUPLING REAGENTS, PROCESS FOR OBTAINING SAME, AND SYNTHETIC INTERMEDIATES

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430935A1 (en) * 1978-07-15 1980-02-08 Antibioticos Sa CARBOXYLIC ACID ACTIVATION PROCESS
FR2643374A1 (en) * 1989-02-23 1990-08-24 Centre Nat Rech Scient TRISTETRAMETHYLENE-AMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATES AS PEPTIDE COUPLING REAGENTS, PROCESS FOR OBTAINING SAME, AND SYNTHETIC INTERMEDIATES
WO1990010009A1 (en) * 1989-02-23 1990-09-07 Centre National De La Recherche Scientifique (Cnrs) Phosphonium salts as peptide coupling reagents

Also Published As

Publication number Publication date
FR2234310B1 (en) 1976-04-30

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Legal Events

Date Code Title Description
ST Notification of lapse