GB1382608A - Vincaminic acid derivatives and their preparation - Google Patents
Vincaminic acid derivatives and their preparationInfo
- Publication number
- GB1382608A GB1382608A GB4771872A GB4771872A GB1382608A GB 1382608 A GB1382608 A GB 1382608A GB 4771872 A GB4771872 A GB 4771872A GB 4771872 A GB4771872 A GB 4771872A GB 1382608 A GB1382608 A GB 1382608A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vincaminate
- acid
- vincaminic acid
- vincaminic
- vincamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UXMCFEBDJVHVNH-HOJAQTOUSA-N ac1l52id Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(O)=O)N5C2=C1 UXMCFEBDJVHVNH-HOJAQTOUSA-N 0.000 title abstract 6
- -1 aminoethyl halide Chemical class 0.000 abstract 6
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 abstract 4
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 abstract 3
- 150000003840 hydrochlorides Chemical class 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical compound [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 abstract 2
- 229960002726 vincamine Drugs 0.000 abstract 2
- RXPRRQLKFXBCSJ-HLAWJBBLSA-N 16-epivincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-HLAWJBBLSA-N 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 abstract 1
- 150000008041 alkali metal carbonates Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000006203 morpholinoethyl group Chemical group [H]C([H])(*)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 235000011056 potassium acetate Nutrition 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE774422A BE774422A (en) | 1971-10-25 | 1971-10-25 | N-disubstd-amino-ethyl vincaminic acid esters - useful as medicaments |
| BE777601A BE777601R (en) | 1971-12-31 | 1971-12-31 | N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1382608A true GB1382608A (en) | 1975-02-05 |
Family
ID=25656949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4771872A Expired GB1382608A (en) | 1971-10-25 | 1972-10-17 | Vincaminic acid derivatives and their preparation |
Country Status (3)
| Country | Link |
|---|---|
| FR (1) | FR2157944B1 (enExample) |
| GB (1) | GB1382608A (enExample) |
| HU (1) | HU165974B (enExample) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1448712A (fr) * | 1962-07-11 | 1966-03-18 | Procédé de préparation d'esters, aminoéthyliques nu-disubstitués des acides réserpilinique et isoréserpilinique et nouveaux esters de ce type | |
| FR1592869A (enExample) * | 1968-11-22 | 1970-05-19 |
-
1972
- 1972-10-17 GB GB4771872A patent/GB1382608A/en not_active Expired
- 1972-10-25 FR FR7237773A patent/FR2157944B1/fr not_active Expired
- 1972-10-25 HU HUOI000157 patent/HU165974B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU165974B (enExample) | 1974-12-28 |
| FR2157944A1 (enExample) | 1973-06-08 |
| FR2157944B1 (enExample) | 1976-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |