BE777601R - N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamine - Google Patents
N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamineInfo
- Publication number
- BE777601R BE777601R BE777601A BE777601A BE777601R BE 777601 R BE777601 R BE 777601R BE 777601 A BE777601 A BE 777601A BE 777601 A BE777601 A BE 777601A BE 777601 R BE777601 R BE 777601R
- Authority
- BE
- Belgium
- Prior art keywords
- vincamine
- disubstd
- prepd
- epi
- transesterification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
Abstract
Title cpds. are prepd. by (a) saponification of 16-epi-vincamine and precipitation at isoelectric pH of the Zwitterion of vincaminic acid which is esterified by the methods of parent patent BE 774422 or (b) by transesterification of vincamine with a disubstd aminoethanol using an alkali metal alcoholate as catalyst. The dihydrochlorides of morpholino-ethyl-, pyrrolidino-ethyl and piperidino-ethyl-vincaminates are new cpds.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE777601A BE777601R (en) | 1971-12-31 | 1971-12-31 | N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamine |
GB4771872A GB1382608A (en) | 1971-10-25 | 1972-10-17 | Vincaminic acid derivatives and their preparation |
HUOI000157 HU165974B (en) | 1971-10-25 | 1972-10-25 | |
FR7237773A FR2157944B1 (en) | 1971-10-25 | 1972-10-25 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE777601A BE777601R (en) | 1971-12-31 | 1971-12-31 | N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamine |
Publications (1)
Publication Number | Publication Date |
---|---|
BE777601R true BE777601R (en) | 1972-04-17 |
Family
ID=3859082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE777601A BE777601R (en) | 1971-10-25 | 1971-12-31 | N-disubstd-amino-ethyl esters of vincaminic acid - - prepd by transesterification of vincamine or from epi-16-vincamine |
Country Status (1)
Country | Link |
---|---|
BE (1) | BE777601R (en) |
-
1971
- 1971-12-31 BE BE777601A patent/BE777601R/en active
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