GB1382073A - Pharmacologically effective substance and its isolation from cabucala madagascariensis - Google Patents
Pharmacologically effective substance and its isolation from cabucala madagascariensisInfo
- Publication number
- GB1382073A GB1382073A GB762572A GB762572A GB1382073A GB 1382073 A GB1382073 A GB 1382073A GB 762572 A GB762572 A GB 762572A GB 762572 A GB762572 A GB 762572A GB 1382073 A GB1382073 A GB 1382073A
- Authority
- GB
- United Kingdom
- Prior art keywords
- water
- isolation
- spectrum
- feb
- hypotensive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241001270491 Petchia madagascariensis Species 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 2
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- NMJJFJNHVMGPGM-UHFFFAOYSA-N butyl formate Chemical compound CCCCOC=O NMJJFJNHVMGPGM-UHFFFAOYSA-N 0.000 abstract 2
- 208000021822 hypotensive Diseases 0.000 abstract 2
- 230000001077 hypotensive effect Effects 0.000 abstract 2
- TZIHFWKZFHZASV-UHFFFAOYSA-N methyl formate Chemical compound COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric Acid Chemical class [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical group ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 235000011054 acetic acid Nutrition 0.000 abstract 1
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- -1 aliphatic halogenated hydrocarbon Chemical class 0.000 abstract 1
- 239000006286 aqueous extract Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000003925 fat Substances 0.000 abstract 1
- WBJINCZRORDGAQ-UHFFFAOYSA-N formic acid ethyl ester Natural products CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 235000011167 hydrochloric acid Nutrition 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 238000001819 mass spectrum Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000003208 petroleum Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 235000011007 phosphoric acid Nutrition 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- UBOXGVDOUJQMTN-UHFFFAOYSA-N trichloroethylene Natural products ClCC(Cl)Cl UBOXGVDOUJQMTN-UHFFFAOYSA-N 0.000 abstract 1
- 238000002211 ultraviolet spectrum Methods 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 239000001993 wax Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712108366 DE2108366A1 (de) | 1971-02-22 | 1971-02-22 | Pharmakologisch wirksamer Stoff und seine Isolierung aus Cabucala madagascariensis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1382073A true GB1382073A (en) | 1975-01-29 |
Family
ID=5799473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB762572A Expired GB1382073A (en) | 1971-02-22 | 1972-02-18 | Pharmacologically effective substance and its isolation from cabucala madagascariensis |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3773931A (enExample) |
| AT (1) | AT319465B (enExample) |
| AU (1) | AU461396B2 (enExample) |
| BE (1) | BE779653A (enExample) |
| CA (1) | CA976542A (enExample) |
| DE (1) | DE2108366A1 (enExample) |
| DK (1) | DK131272B (enExample) |
| FR (1) | FR2126244B1 (enExample) |
| GB (1) | GB1382073A (enExample) |
| HU (1) | HU163554B (enExample) |
| IL (1) | IL38800A (enExample) |
| NL (1) | NL7202100A (enExample) |
| OA (1) | OA03966A (enExample) |
| RO (1) | RO61141A (enExample) |
| SE (1) | SE390107B (enExample) |
| ZA (1) | ZA721130B (enExample) |
-
1971
- 1971-02-22 DE DE19712108366 patent/DE2108366A1/de active Pending
-
1972
- 1972-02-16 RO RO69779A patent/RO61141A/ro unknown
- 1972-02-17 NL NL7202100A patent/NL7202100A/xx unknown
- 1972-02-18 GB GB762572A patent/GB1382073A/en not_active Expired
- 1972-02-20 IL IL38800A patent/IL38800A/xx unknown
- 1972-02-21 AT AT139872A patent/AT319465B/de not_active IP Right Cessation
- 1972-02-21 ZA ZA721130A patent/ZA721130B/xx unknown
- 1972-02-21 FR FR7205738A patent/FR2126244B1/fr not_active Expired
- 1972-02-21 DK DK79972AA patent/DK131272B/da unknown
- 1972-02-21 AU AU39172/72A patent/AU461396B2/en not_active Expired
- 1972-02-21 OA OA54497A patent/OA03966A/xx unknown
- 1972-02-21 CA CA135,233A patent/CA976542A/en not_active Expired
- 1972-02-22 BE BE779653A patent/BE779653A/xx unknown
- 1972-02-22 SE SE7202121A patent/SE390107B/xx unknown
- 1972-02-22 US US00227919A patent/US3773931A/en not_active Expired - Lifetime
- 1972-02-22 HU HUHO1457A patent/HU163554B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL38800A0 (en) | 1972-04-27 |
| DE2108366A1 (de) | 1972-09-07 |
| HU163554B (enExample) | 1973-09-27 |
| ZA721130B (en) | 1972-11-29 |
| CA976542A (en) | 1975-10-21 |
| NL7202100A (enExample) | 1972-08-24 |
| BE779653A (fr) | 1972-08-22 |
| OA03966A (fr) | 1979-08-31 |
| FR2126244B1 (enExample) | 1975-03-14 |
| DK131272B (da) | 1975-06-23 |
| AT319465B (de) | 1974-12-27 |
| AU461396B2 (en) | 1975-05-08 |
| FR2126244A1 (enExample) | 1972-10-06 |
| SE390107B (sv) | 1976-12-06 |
| RO61141A (enExample) | 1977-02-15 |
| IL38800A (en) | 1974-12-31 |
| AU3917272A (en) | 1973-08-23 |
| DK131272C (enExample) | 1975-11-17 |
| US3773931A (en) | 1973-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |