GB1380056A - Process for isolating a fibrin-stabilizing factor - Google Patents
Process for isolating a fibrin-stabilizing factorInfo
- Publication number
- GB1380056A GB1380056A GB5972271A GB5972271A GB1380056A GB 1380056 A GB1380056 A GB 1380056A GB 5972271 A GB5972271 A GB 5972271A GB 5972271 A GB5972271 A GB 5972271A GB 1380056 A GB1380056 A GB 1380056A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solution
- neutral
- weight
- alkali metal
- lactate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010071289 Factor XIII Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
- 230000007935 neutral effect Effects 0.000 abstract 4
- 239000002244 precipitate Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 2
- 229910001514 alkali metal chloride Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- VRQURTHVUQBIMS-UHFFFAOYSA-N 2-acridin-1-yloxyethane-1,1-diamine;2-hydroxypropanoic acid Chemical compound CC(O)C(O)=O.C1=CC=C2C=C3C(OCC(N)N)=CC=CC3=NC2=C1 VRQURTHVUQBIMS-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000356 contaminant Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000012064 sodium phosphate buffer Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000010414 supernatant solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2063070A DE2063070C3 (de) | 1970-12-22 | 1970-12-22 | Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380056A true GB1380056A (en) | 1975-01-08 |
Family
ID=5791794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5972271A Expired GB1380056A (en) | 1970-12-22 | 1971-12-22 | Process for isolating a fibrin-stabilizing factor |
Country Status (15)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2124900A (en) * | 1982-12-10 | 1984-02-29 | Cubana Importadora Y Exportado | Product for stimulating the synthesis of melanotic pigment in the skin |
| WO1991000098A1 (en) * | 1989-06-23 | 1991-01-10 | Kishinevsky Selskokhozyaistvenny Institut Imeni M.V.Frunze | Anti-inflammatory preparation and method of obtaining it |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2600078B1 (fr) * | 1986-06-12 | 1989-07-13 | Merieux Inst | Procede de preparation de facteur xiii a partir du placenta |
| DE3734923C1 (de) * | 1987-10-15 | 1989-01-26 | Biotest Pharma Gmbh | Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt |
| JPH01216939A (ja) * | 1988-02-24 | 1989-08-30 | Hoechst Japan Kk | 末熟児頭蓋内出血阻止剤 |
| DE3808048A1 (de) * | 1988-03-11 | 1989-09-21 | Behringwerke Ag | Verfahren zum affinitaetschromatografischen reinigen von faktor xiii |
| DE19508192A1 (de) | 1995-03-09 | 1996-09-12 | Behringwerke Ag | Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung |
-
1970
- 1970-12-22 DE DE2063070A patent/DE2063070C3/de not_active Expired
-
1971
- 1971-12-16 ES ES398016A patent/ES398016A1/es not_active Expired
- 1971-12-17 NL NL7117363.A patent/NL159582B/xx not_active IP Right Cessation
- 1971-12-17 CH CH1850871A patent/CH575235A5/xx not_active IP Right Cessation
- 1971-12-20 SE SE7116299A patent/SE371930B/xx unknown
- 1971-12-20 AU AU37088/71A patent/AU432182B2/en not_active Expired
- 1971-12-20 IL IL38403A patent/IL38403A/xx unknown
- 1971-12-20 CA CA130,488A patent/CA957943A/en not_active Expired
- 1971-12-21 AT AT1096271A patent/AT310941B/de not_active IP Right Cessation
- 1971-12-21 DK DK626471AA patent/DK127227B/da unknown
- 1971-12-22 BR BR8490/71A patent/BR7108490D0/pt unknown
- 1971-12-22 GB GB5972271A patent/GB1380056A/en not_active Expired
- 1971-12-22 BE BE777136A patent/BE777136A/xx unknown
- 1971-12-22 FR FR7146139A patent/FR2119009B1/fr not_active Expired
- 1971-12-22 JP JP10451871A patent/JPS5421402B1/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2124900A (en) * | 1982-12-10 | 1984-02-29 | Cubana Importadora Y Exportado | Product for stimulating the synthesis of melanotic pigment in the skin |
| WO1991000098A1 (en) * | 1989-06-23 | 1991-01-10 | Kishinevsky Selskokhozyaistvenny Institut Imeni M.V.Frunze | Anti-inflammatory preparation and method of obtaining it |
Also Published As
| Publication number | Publication date |
|---|---|
| BR7108490D0 (pt) | 1973-05-08 |
| SE371930B (enrdf_load_stackoverflow) | 1974-12-09 |
| IL38403A (en) | 1975-04-25 |
| DE2063070B2 (de) | 1974-12-05 |
| CH575235A5 (enrdf_load_stackoverflow) | 1976-05-14 |
| FR2119009B1 (enrdf_load_stackoverflow) | 1975-03-14 |
| DE2063070C3 (de) | 1975-07-24 |
| NL159582B (nl) | 1979-03-15 |
| DK127227B (da) | 1973-10-08 |
| FR2119009A1 (enrdf_load_stackoverflow) | 1972-08-04 |
| AU3708871A (en) | 1973-02-15 |
| JPS5421402B1 (enrdf_load_stackoverflow) | 1979-07-30 |
| ES398016A1 (es) | 1974-07-16 |
| AU432182B2 (en) | 1973-02-15 |
| BE777136A (fr) | 1972-06-22 |
| DE2063070A1 (de) | 1972-06-29 |
| NL7117363A (enrdf_load_stackoverflow) | 1972-06-26 |
| IL38403A0 (en) | 1972-02-29 |
| AT310941B (de) | 1973-10-25 |
| CA957943A (en) | 1974-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |