GB1377318A - 2-amino-4 -3h-pteridinones - Google Patents
2-amino-4 -3h-pteridinonesInfo
- Publication number
- GB1377318A GB1377318A GB3006073A GB3006073A GB1377318A GB 1377318 A GB1377318 A GB 1377318A GB 3006073 A GB3006073 A GB 3006073A GB 3006073 A GB3006073 A GB 3006073A GB 1377318 A GB1377318 A GB 1377318A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- compound
- alkoxy
- group
- alkylthio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HNXQXTQTPAJEJL-UHFFFAOYSA-N 2-aminopteridin-4-ol Chemical class C1=CN=C2NC(N)=NC(=O)C2=N1 HNXQXTQTPAJEJL-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical compound O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 abstract 2
- UZFMOKQJFYMBGY-UHFFFAOYSA-N 4-hydroxy-TEMPO Chemical compound CC1(C)CC(O)CC(C)(C)N1[O] UZFMOKQJFYMBGY-UHFFFAOYSA-N 0.000 abstract 1
- 229940126062 Compound A Drugs 0.000 abstract 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- -1 acetal oxime Chemical class 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 230000029142 excretion Effects 0.000 abstract 1
- 229940015043 glyoxal Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000007857 hydrazones Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 1
- 235000010265 sodium sulphite Nutrition 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2232097A DE2232097A1 (de) | 1972-06-30 | 1972-06-30 | 2-amino-4(3h)-pteridinone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1377318A true GB1377318A (en) | 1974-12-11 |
Family
ID=5849287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3006073A Expired GB1377318A (en) | 1972-06-30 | 1973-06-25 | 2-amino-4 -3h-pteridinones |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS50100080A (cs) |
| AR (3) | AR196772A1 (cs) |
| AU (1) | AU5762573A (cs) |
| DD (1) | DD106173A5 (cs) |
| DE (1) | DE2232097A1 (cs) |
| FR (1) | FR2190452A1 (cs) |
| GB (1) | GB1377318A (cs) |
| NL (1) | NL7308927A (cs) |
| ZA (1) | ZA734372B (cs) |
-
1972
- 1972-06-30 DE DE2232097A patent/DE2232097A1/de active Pending
-
1973
- 1973-06-25 GB GB3006073A patent/GB1377318A/en not_active Expired
- 1973-06-25 DD DD171797A patent/DD106173A5/xx unknown
- 1973-06-26 FR FR7323272A patent/FR2190452A1/fr not_active Withdrawn
- 1973-06-27 ZA ZA734372A patent/ZA734372B/xx unknown
- 1973-06-27 NL NL7308927A patent/NL7308927A/xx unknown
- 1973-06-29 AR AR248852A patent/AR196772A1/es active
- 1973-06-29 JP JP48073542A patent/JPS50100080A/ja active Pending
- 1973-07-02 AU AU57625/73A patent/AU5762573A/en not_active Expired
- 1973-12-14 AR AR251521A patent/AR196836A1/es active
- 1973-12-14 AR AR251520A patent/AR196835A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| NL7308927A (cs) | 1974-01-02 |
| JPS50100080A (cs) | 1975-08-08 |
| DD106173A5 (cs) | 1974-06-05 |
| ZA734372B (en) | 1974-06-26 |
| DE2232097A1 (de) | 1974-01-17 |
| AR196772A1 (es) | 1974-02-19 |
| AR196836A1 (es) | 1974-02-19 |
| FR2190452A1 (cs) | 1974-02-01 |
| AR196835A1 (es) | 1974-02-19 |
| AU5762573A (en) | 1975-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |