GB1375880A - - Google Patents

Info

Publication number
GB1375880A
GB1375880A GB2103972A GB2103972A GB1375880A GB 1375880 A GB1375880 A GB 1375880A GB 2103972 A GB2103972 A GB 2103972A GB 2103972 A GB2103972 A GB 2103972A GB 1375880 A GB1375880 A GB 1375880A
Authority
GB
United Kingdom
Prior art keywords
copper
salt
excess
myxin
stabilizer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2103972A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1375880A publication Critical patent/GB1375880A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1375880 Stabilized compositions containing copper myxin F HOFFMANN-LA ROCHE & CO AG 5 May 1972 [7 May 1971] 21039/72 Heading A5B Pharmaceutical compositions having antimicrobial activity against Gram-positive and -negative bacteria, fungi, protozoa and helminths contain, as the active ingredient, the copper II complex of 6-methoxy-1-phenazinol 5, 10-dioxide (copper myxin) and, as a stabilizer, from 2 to 20% molar excess of copper II ions based on the copper content in the copper II complex, the excess of copper II ions being provided by a water-soluble copper II salt. The excess copper may originate from a stabilizer-buffer solution comprising a watersoluble copper II salt e.g. copper II acetate, in an aqueous solution buffered at pH 5.7-6.2 by the use of an alkali metal salt having the same anionic moiety as the copper II salt e.g. sodium acetate, and the corresponding acid e.g. acetic acid. The compositions may be administered topically in the form of creams or suspensions.
GB2103972A 1971-05-07 1972-05-05 Expired GB1375880A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14138271A 1971-05-07 1971-05-07

Publications (1)

Publication Number Publication Date
GB1375880A true GB1375880A (en) 1974-11-27

Family

ID=22495452

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2103972A Expired GB1375880A (en) 1971-05-07 1972-05-05

Country Status (9)

Country Link
JP (1) JPS5653549B1 (en)
BE (1) BE783054A (en)
CA (1) CA979361A (en)
CH (1) CH574741A5 (en)
DE (1) DE2216911C2 (en)
FR (1) FR2137543B1 (en)
GB (1) GB1375880A (en)
NL (1) NL7204770A (en)
SE (1) SE419287B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL32324A (en) * 1968-06-24 1972-01-27 Sparamedica Ag Phenazine derivatives and their preparation

Also Published As

Publication number Publication date
CH574741A5 (en) 1976-04-30
SE419287B (en) 1981-07-27
DE2216911A1 (en) 1972-11-23
DE2216911C2 (en) 1981-09-17
JPS5653549B1 (en) 1981-12-19
FR2137543A1 (en) 1972-12-29
NL7204770A (en) 1972-11-09
BE783054A (en) 1972-11-06
CA979361A (en) 1975-12-09
FR2137543B1 (en) 1975-10-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee