GB1375139A - - Google Patents
Info
- Publication number
- GB1375139A GB1375139A GB2265973A GB2265973A GB1375139A GB 1375139 A GB1375139 A GB 1375139A GB 2265973 A GB2265973 A GB 2265973A GB 2265973 A GB2265973 A GB 2265973A GB 1375139 A GB1375139 A GB 1375139A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- amino
- hydroxyalkyl
- hydroxymethyl
- hydroxyethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002118 epoxides Chemical class 0.000 abstract 2
- -1 hydroxyalkoxyalkyl Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- ZURMQCTYVXKSPN-UHFFFAOYSA-N 3-(1-hydroxyethyl)-5-nitrobenzoic acid Chemical compound CC(O)C1=CC(C(O)=O)=CC([N+]([O-])=O)=C1 ZURMQCTYVXKSPN-UHFFFAOYSA-N 0.000 abstract 1
- IJSPTRYNIILJCH-UHFFFAOYSA-N 3-acetamido-5-(1-acetyloxyethyl)-2,4,6-triiodobenzoic acid Chemical compound C(C)(=O)OC(C)C=1C(=C(C(=O)O)C(=C(C=1I)NC(C)=O)I)I IJSPTRYNIILJCH-UHFFFAOYSA-N 0.000 abstract 1
- QCKOQFBTVRJTRZ-UHFFFAOYSA-N 3-amino-5-(1-hydroxyethyl)-2,4,6-triiodobenzoic acid Chemical compound OC(C)C=1C(=C(C(=O)O)C(=C(C=1I)N)I)I QCKOQFBTVRJTRZ-UHFFFAOYSA-N 0.000 abstract 1
- SZSPDPNRUBMWFF-UHFFFAOYSA-N 3-amino-5-(1-hydroxyethyl)benzoic acid Chemical compound OC(C)C=1C=C(C(=O)O)C=C(C=1)N SZSPDPNRUBMWFF-UHFFFAOYSA-N 0.000 abstract 1
- VGEZCDZTFHVHTC-UHFFFAOYSA-N 3-amino-5-(hydroxymethyl)-2,4,6-triiodobenzoic acid Chemical compound NC1=C(I)C(CO)=C(I)C(C(O)=O)=C1I VGEZCDZTFHVHTC-UHFFFAOYSA-N 0.000 abstract 1
- WQQQFKJMOWXDPO-UHFFFAOYSA-N 3-amino-5-(hydroxymethyl)benzoic acid Chemical compound NC1=CC(CO)=CC(C(O)=O)=C1 WQQQFKJMOWXDPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000004689 alkyl amino carbonyl alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000005097 aminocarbonylalkyl group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 125000004990 dihydroxyalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- NNMLFVLQJJIINL-UHFFFAOYSA-N methyl 3-(hydroxymethyl)-5-nitrobenzoate Chemical compound COC(=O)C1=CC(CO)=CC([N+]([O-])=O)=C1 NNMLFVLQJJIINL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- RPACBEVZENYWOL-XFULWGLBSA-M sodium;(2r)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Chemical compound [Na+].C=1C=C(Cl)C=CC=1OCCCCCC[C@]1(C(=O)[O-])CO1 RPACBEVZENYWOL-XFULWGLBSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0452—Solutions, e.g. for injection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1683272A CH576255A5 (enrdf_load_stackoverflow) | 1972-11-17 | 1972-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1375139A true GB1375139A (enrdf_load_stackoverflow) | 1974-11-27 |
Family
ID=4420614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2265973A Expired GB1375139A (enrdf_load_stackoverflow) | 1972-11-17 | 1973-05-11 |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH576255A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2317535A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2258844A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1375139A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5882628A (en) * | 1994-09-23 | 1999-03-16 | Nycomed Imaging As | Contrast media |
| AU710934B2 (en) * | 1994-09-23 | 1999-09-30 | Nycomed Imaging As | Iodinated X-ray-contrast media |
-
1972
- 1972-11-17 CH CH1683272A patent/CH576255A5/xx not_active IP Right Cessation
-
1973
- 1973-04-07 DE DE19732317535 patent/DE2317535A1/de active Pending
- 1973-05-11 GB GB2265973A patent/GB1375139A/en not_active Expired
- 1973-09-25 FR FR7334305A patent/FR2258844A1/fr not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5882628A (en) * | 1994-09-23 | 1999-03-16 | Nycomed Imaging As | Contrast media |
| AU710330B2 (en) * | 1994-09-23 | 1999-09-16 | Nycomed Imaging As | Iodinated X-ray contrast media |
| AU710934B2 (en) * | 1994-09-23 | 1999-09-30 | Nycomed Imaging As | Iodinated X-ray-contrast media |
| CN1069633C (zh) * | 1994-09-23 | 2001-08-15 | 尼科梅德成像有限公司 | 碘代x-射线造影剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| CH576255A5 (enrdf_load_stackoverflow) | 1976-06-15 |
| DE2317535A1 (de) | 1974-05-30 |
| FR2258844A1 (enrdf_load_stackoverflow) | 1975-08-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed |